| MeSH term | MeSH ID | Detail |
|---|---|---|
| Hemolysis | D006461 | 131 associated lipids |
| Carcinoma, Hepatocellular | D006528 | 140 associated lipids |
| Hypercholesterolemia | D006937 | 91 associated lipids |
| Hyperlipidemias | D006949 | 73 associated lipids |
| Hyperlipidemia, Familial Combined | D006950 | 9 associated lipids |
| Hypersensitivity | D006967 | 22 associated lipids |
| Hypersensitivity, Delayed | D006968 | 43 associated lipids |
| Hypertension | D006973 | 115 associated lipids |
| Inflammation | D007249 | 119 associated lipids |
| Insect Bites and Stings | D007299 | 4 associated lipids |
| Insulin Resistance | D007333 | 99 associated lipids |
| Learning Disorders | D007859 | 11 associated lipids |
| Lipid Metabolism, Inborn Errors | D008052 | 26 associated lipids |
| Liver Diseases | D008107 | 31 associated lipids |
| Long QT Syndrome | D008133 | 10 associated lipids |
| Lung Neoplasms | D008175 | 171 associated lipids |
| Metabolism, Inborn Errors | D008661 | 46 associated lipids |
| Myocardial Infarction | D009203 | 21 associated lipids |
| Neoplasms | D009369 | 13 associated lipids |
| Neuroblastoma | D009447 | 66 associated lipids |
alpha-linolenic acid
Alpha-linolenic acid is a lipid of Fatty Acyls (FA) class. Alpha-linolenic acid is associated with abnormalities such as Coronary heart disease, abnormal fragmented structure, Arterial thrombosis and Subarachnoid Hemorrhage. The involved functions are known as Anabolism, Signal, Transcription, Genetic, Saturated and Regulation. Alpha-linolenic acid often locates in Blood, Body tissue, Plasma membrane, Hepatic and peroxisome. The associated genes with alpha-linolenic acid are FATE1 gene, volicitin, CYP2U1 gene, CYP1A2 gene and CYP2J2 gene. The related lipids are Fatty Acids, Dietary Fatty Acid, stearidonic acid and Fatty Acids, Nonesterified.
Cross Reference
Introduction
To understand associated biological information of alpha-linolenic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with alpha-linolenic acid?
alpha-linolenic acid is suspected in Coronary heart disease, Arterial thrombosis, Subarachnoid Hemorrhage and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with alpha-linolenic acid
PubChem Associated disorders and diseases
What pathways are associated with alpha-linolenic acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with alpha-linolenic acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with alpha-linolenic acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with alpha-linolenic acid?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with alpha-linolenic acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with alpha-linolenic acid?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with alpha-linolenic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Crawford M et al. | Role of plant-derived omega-3 fatty acids in human nutrition. | 2000 | Ann. Nutr. Metab. | pmid:11146334 |
| Utsunomiya T et al. | Correspondence re: M. Kondo et al., Increased expression of COX-2 in nontumor liver tissue is associated with shorter disease-free survival in patients with hepatocellular carcinoma. Clin. Cancer Res., 5: 4005-4012, 1999. | 2000 | Clin. Cancer Res. | pmid:11156258 |
| Cho E et al. | Prospective study of dietary fat and the risk of age-related macular degeneration. | 2001 | Am. J. Clin. Nutr. | pmid:11157315 |
| Tocher DR and Dick JR | Effects of essential fatty acid deficiency and supplementation with docosahexaenoic acid (DHA; 22:6n-3) on cellular fatty acid compositions and fatty acyl desaturation in a cell culture model. | 2001 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:11161581 |
| Soppela P and Nieminen M | The effect of wintertime undernutrition on the fatty acid composition of leg bone marrow fats in reindeer (Rangifer tarandus tarandus L.). | 2001 | Comp. Biochem. Physiol. B, Biochem. Mol. Biol. | pmid:11163305 |
| Wiesenfeld PW et al. | Effect of long-chain fatty acids in the culture medium on fatty acid composition of WEHI-3 and J774A.1 cells. | 2001 | Comp. Biochem. Physiol. B, Biochem. Mol. Biol. | pmid:11163311 |
| Dikalov SI and Mason RP | Spin trapping of polyunsaturated fatty acid-derived peroxyl radicals: reassignment to alkoxyl radical adducts. | 2001 | Free Radic. Biol. Med. | pmid:11163536 |
| Kaushik N and Agnihotri A | GLC analysis of Indian rapeseed-mustard to study the variability of fatty acid composition. | 2000 | Biochem. Soc. Trans. | pmid:11171132 |
| Dobson G | Leaf lipids of Ribes nigrum: a plant containing 16:3, alpha-18:3, gamma-18:3 and 18:4 fatty acids. | 2000 | Biochem. Soc. Trans. | pmid:11171133 |
| Grechkin AN et al. | Lipoxygenase pathway in tulip: biosynthesis of ketols. | 2000 | Biochem. Soc. Trans. | pmid:11171230 |
| Radunz A et al. | State of the lipid and fatty acid composition in chloroplasts of Nicotiana tabacum under the influence of an increased CO2 partial pressure of 700 p.p.m. | 2000 | Biochem. Soc. Trans. | pmid:11171245 |
| Nuñez A et al. | Anaerobic lipoxygenase activity from Chlorella pyrenoidosa. | 2000 | Biochem. Soc. Trans. | pmid:11171268 |
| Schaller F | Enzymes of the biosynthesis of octadecanoid-derived signalling molecules. | 2001 | J. Exp. Bot. | pmid:11181709 |
| Fein A and Cavar S | Divergent mechanisms for phototransduction of invertebrate microvillar photoreceptors. | 2000 Nov-Dec | Vis. Neurosci. | pmid:11193107 |
| Cheon SH et al. | Effect of dietary linoleate/alpha-linolenate balance on the brain lipid composition, reproductive outcome and behavior of rats during their prenatal and postnatal development. | 2000 | Biosci. Biotechnol. Biochem. | pmid:11193394 |
| Du M et al. | Effects of dietary conjugated linoleic acid and linoleic:linolenic acid ratio on polyunsaturated fatty acid status in laying hens. | 2000 | Poult. Sci. | pmid:11194037 |
| Rao GN et al. | Effect of melatonin and linolenic acid on mammary cancer in transgenic mice with c-neu breast cancer oncogene. | 2000 | Breast Cancer Res. Treat. | pmid:11200779 |
| Choi SB et al. | Transcriptional expression characteristics and subcellular localization of ADP-glucose pyrophosphorylase in the oil plant Perilla frutescens. | 2001 | Plant Cell Physiol. | pmid:11230568 |
| Ide T | Effect of dietary alpha-linolenic acid on the activity and gene expression of hepatic fatty acid oxidation enzymes. | 2000 | Biofactors | pmid:11237206 |
| Thies F et al. | Dietary supplementation with eicosapentaenoic acid, but not with other long-chain n-3 or n-6 polyunsaturated fatty acids, decreases natural killer cell activity in healthy subjects aged >55 y. | 2001 | Am. J. Clin. Nutr. | pmid:11237929 |