alpha-linolenic acid

Alpha-linolenic acid is a lipid of Fatty Acyls (FA) class. Alpha-linolenic acid is associated with abnormalities such as Coronary heart disease, abnormal fragmented structure, Arterial thrombosis and Subarachnoid Hemorrhage. The involved functions are known as Anabolism, Signal, Transcription, Genetic, Saturated and Regulation. Alpha-linolenic acid often locates in Blood, Body tissue, Plasma membrane, Hepatic and peroxisome. The associated genes with alpha-linolenic acid are FATE1 gene, volicitin, CYP2U1 gene, CYP1A2 gene and CYP2J2 gene. The related lipids are Fatty Acids, Dietary Fatty Acid, stearidonic acid and Fatty Acids, Nonesterified.

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Introduction

To understand associated biological information of alpha-linolenic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with alpha-linolenic acid?

alpha-linolenic acid is suspected in Coronary heart disease, Arterial thrombosis, Subarachnoid Hemorrhage and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with alpha-linolenic acid

MeSH term MeSH ID Detail
Irritable Bowel Syndrome D043183 8 associated lipids
Overweight D050177 11 associated lipids
Atherosclerosis D050197 85 associated lipids
Carcinogenesis D063646 3 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with alpha-linolenic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with alpha-linolenic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with alpha-linolenic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with alpha-linolenic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with alpha-linolenic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with alpha-linolenic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with alpha-linolenic acid

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Authors Title Published Journal PubMed Link
Thamphiwatana S et al. In vivo treatment of Helicobacter pylori infection with liposomal linolenic acid reduces colonization and ameliorates inflammation. 2014 Proc. Natl. Acad. Sci. U.S.A. pmid:25422427
Alvarado-Gilis CA et al. Effects of feeding diets rich in α-linolenic acid and copper on performance, carcass characteristics, and fatty acid profiles of feedlot heifers. 2014 J. Anim. Sci. pmid:25414107
Liu J and Ma DW The role of n-3 polyunsaturated fatty acids in the prevention and treatment of breast cancer. 2014 Nutrients pmid:25412153
Eastwood L et al. Changing the omega-6 to omega-3 fatty acid ratio in sow diets alters serum, colostrum, and milk fatty acid profiles, but has minimal impact on reproductive performance. 2014 J. Anim. Sci. pmid:25403193
Fleming JA and Kris-Etherton PM The evidence for α-linolenic acid and cardiovascular disease benefits: Comparisons with eicosapentaenoic acid and docosahexaenoic acid. 2014 Adv Nutr pmid:25398754
Zhu G et al. Enhanced production of docosahexaenoic acid in mammalian cells. 2014 PLoS ONE pmid:24788769
Enos RT et al. Reducing the dietary omega-6:omega-3 utilizing α-linolenic acid; not a sufficient therapy for attenuating high-fat-diet-induced obesity development nor related detrimental metabolic and adipose tissue inflammatory outcomes. 2014 PLoS ONE pmid:24733548
Papanikolaou Y et al. U.S. adults are not meeting recommended levels for fish and omega-3 fatty acid intake: results of an analysis using observational data from NHANES 2003-2008. 2014 Nutr J pmid:24694001
Burns-Whitmore B et al. Effects of supplementing n-3 fatty acid enriched eggs and walnuts on cardiovascular disease risk markers in healthy free-living lacto-ovo-vegetarians: a randomized, crossover, free-living intervention study. 2014 Nutr J pmid:24673793
Jung JY et al. Effect of dietary supplementation with omega-3 fatty acid and gamma-linolenic acid on acne vulgaris: a randomised, double-blind, controlled trial. 2014 Acta Derm. Venereol. pmid:24553997
Qin G et al. Evolution of the aroma volatiles of pear fruits supplemented with fatty acid metabolic precursors. 2014 Molecules pmid:25474290
Ladeira MM et al. Fatty acid profile, color and lipid oxidation of meat from young bulls fed ground soybean or rumen protected fat with or without monensin. 2014 Meat Sci. pmid:24018278
Shimada TL et al. Leaf oil body functions as a subcellular factory for the production of a phytoalexin in Arabidopsis. 2014 Plant Physiol. pmid:24214535
Singer SD et al. Development and characterization of low α-linolenic acid Brassica oleracea lines bearing a novel mutation in a 'class a' FATTY ACID DESATURASE 3 gene. 2014 BMC Genet. pmid:25167929
Petzinger C et al. Conversion of α-linolenic acid to long-chain omega-3 fatty acid derivatives and alterations of HDL density subfractions and plasma lipids with dietary polyunsaturated fatty acids in Monk parrots (Myiopsitta monachus). 2014 J Anim Physiol Anim Nutr (Berl) pmid:23600588
Sugasini D et al. Lymphatic transport of α-linolenic acid and its conversion to long chain n-3 fatty acids in rats fed microemulsions of linseed oil. 2014 Lipids pmid:24338560
Wu MH et al. A novel sodium N-fatty acyl amino acid surfactant using silkworm pupae as stock material. 2014 Sci Rep pmid:24651079
Reiner WB et al. Fatty acids in mountain gorilla diets: implications for primate nutrition and health. 2014 Am. J. Primatol. pmid:24243235
Canetti L et al. Linoleic and alpha linolenic acids ameliorate streptozotocin-induced diabetes in mice. 2014 Arch. Physiol. Biochem. pmid:24320056
Ambrozova JV et al. Influence of extractive solvents on lipid and fatty acids content of edible freshwater algal and seaweed products, the green Microalga Chlorella kessleri and the Cyanobacterium Spirulina platensis. 2014 Molecules pmid:24566307