| MeSH term | MeSH ID | Detail |
|---|---|---|
| Edema | D004487 | 152 associated lipids |
| Precancerous Conditions | D011230 | 48 associated lipids |
| Arthritis | D001168 | 41 associated lipids |
| Amyloidosis | D000686 | 4 associated lipids |
| Heart Failure | D006333 | 36 associated lipids |
| Coronary Disease | D003327 | 70 associated lipids |
| Liver Diseases | D008107 | 31 associated lipids |
| Hypersensitivity | D006967 | 22 associated lipids |
| Weight Gain | D015430 | 101 associated lipids |
| Hypersensitivity, Delayed | D006968 | 43 associated lipids |
alpha-linolenic acid
Alpha-linolenic acid is a lipid of Fatty Acyls (FA) class. Alpha-linolenic acid is associated with abnormalities such as Coronary heart disease, abnormal fragmented structure, Arterial thrombosis and Subarachnoid Hemorrhage. The involved functions are known as Anabolism, Signal, Transcription, Genetic, Saturated and Regulation. Alpha-linolenic acid often locates in Blood, Body tissue, Plasma membrane, Hepatic and peroxisome. The associated genes with alpha-linolenic acid are FATE1 gene, volicitin, CYP2U1 gene, CYP1A2 gene and CYP2J2 gene. The related lipids are Fatty Acids, Dietary Fatty Acid, stearidonic acid and Fatty Acids, Nonesterified.
Cross Reference
Introduction
To understand associated biological information of alpha-linolenic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with alpha-linolenic acid?
alpha-linolenic acid is suspected in Coronary heart disease, Arterial thrombosis, Subarachnoid Hemorrhage and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with alpha-linolenic acid
PubChem Associated disorders and diseases
What pathways are associated with alpha-linolenic acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with alpha-linolenic acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with alpha-linolenic acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with alpha-linolenic acid?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with alpha-linolenic acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with alpha-linolenic acid?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with alpha-linolenic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Moore SA et al. | Docosahexaenoic acid synthesis in human skin fibroblasts involves peroxisomal retroconversion of tetracosahexaenoic acid. | 1995 | J. Lipid Res. | pmid:8656081 |
| Furono K et al. | Effects of metal ions on lipid peroxidation in cultured rat hepatocytes loaded with alpha-linolenic acid. | 1996 | J Toxicol Environ Health | pmid:8642620 |
| Frances H et al. | Effect of dietary alpha-linolenic acid deficiency on habituation. | 1996 | Life Sci. | pmid:8637406 |
| Delion S et al. | alpha-Linolenic acid dietary deficiency alters age-related changes of dopaminergic and serotoninergic neurotransmission in the rat frontal cortex. | 1996 | J. Neurochem. | pmid:8627314 |
| Carlson SE et al. | Effect of long-chain n-3 fatty acid supplementation on visual acuity and growth of preterm infants with and without bronchopulmonary dysplasia. | 1996 | Am. J. Clin. Nutr. | pmid:8615350 |
| Lhuillery C et al. | Time-course study of adipose tissue fatty acid composition during mammary tumor growth in rats with controlled fat intake. | 1995 | Nutr Cancer | pmid:8610049 |
| Ntambi JM et al. | A model cell line to study regulation of stearoyl-CoA desaturase gene 1 expression by insulin and polyunsaturated fatty acids. | 1996 | Biochem. Biophys. Res. Commun. | pmid:8607881 |
| Yiin SJ and Lin TH | Lead-catalyzed peroxidation of essential unsaturated fatty acid. | 1995 | Biol Trace Elem Res | pmid:8605084 |
| Siguel EN | Dietary sources of long-chain n-3 polyunsaturated fatty acids. | 1996 | JAMA | pmid:8596214 |
| Guil JL et al. | Identification of fatty acids in edible wild plants by gas chromatography. | 1996 | J Chromatogr A | pmid:8589832 |
| Périchon R and Bourre JM | Peroxisomal beta-oxidation activity and catalase activity during development and aging in mouse liver. | 1995 | Biochimie | pmid:8589059 |
| Fuhrmann H and Sallmann HP | Alpha-tocopherol and phospholipase A2 in liver and brain of chicks posthatching: the influence of dietary fat and vitamin E. | 1995 | Ann. Nutr. Metab. | pmid:8585700 |
| Iliou JP et al. | Monohydroperoxidized fatty acids but not 4-hydroxynonenal induced acute cardiac cell damage. | 1995 | Free Radic. Biol. Med. | pmid:8582650 |
| Shoda R et al. | Therapeutic efficacy of N-3 polyunsaturated fatty acid in experimental Crohn's disease. | 1995 | J. Gastroenterol. | pmid:8563904 |
| Buzzi M et al. | The desaturation and elongation of linolenic acid and eicosapentaenoic acid by hepatocytes and liver microsomes from rainbow trout (Oncorhynchus mykiss) fed diets containing fish oil or olive oil. | 1996 | Biochim. Biophys. Acta | pmid:8555269 |
| Harbige LS et al. | Prevention of experimental autoimmune encephalomyelitis in Lewis rats by a novel fungal source of gamma-linolenic acid. | 1995 | Br. J. Nutr. | pmid:8541276 |
| Antras-Ferry J et al. | Fatty acids and fibrates are potent inducers of transcription of the phosphenolpyruvate carboxykinase gene in adipocytes. | 1995 | Eur. J. Biochem. | pmid:8536680 |
| Fournier J et al. | [Lipid peroxidation in the presence of inorganic compounds. Relation to oxidative stress mechanisms]. | 1995 | C. R. Seances Soc. Biol. Fil. | pmid:8521091 |
| Kawashima Y et al. | Modulation by dietary oils and clofibric acid of arachidonic acid content in phosphatidylcholine in liver and kidney of rat: effects on prostaglandin formation in kidney. | 1994 | Biochim. Biophys. Acta | pmid:8280769 |
| Kawashima Y and Kozuka H | Dietary manipulation by perilla oil and fish oil of hepatic lipids and its influence on peroxisomal beta-oxidation and serum lipids in rat and mouse. | 1993 | Biol. Pharm. Bull. | pmid:8130766 |