| MeSH term | MeSH ID | Detail |
|---|---|---|
| Edema | D004487 | 152 associated lipids |
| Precancerous Conditions | D011230 | 48 associated lipids |
| Arthritis | D001168 | 41 associated lipids |
| Amyloidosis | D000686 | 4 associated lipids |
| Heart Failure | D006333 | 36 associated lipids |
| Coronary Disease | D003327 | 70 associated lipids |
| Liver Diseases | D008107 | 31 associated lipids |
| Hypersensitivity | D006967 | 22 associated lipids |
| Weight Gain | D015430 | 101 associated lipids |
| Hypersensitivity, Delayed | D006968 | 43 associated lipids |
alpha-linolenic acid
Alpha-linolenic acid is a lipid of Fatty Acyls (FA) class. Alpha-linolenic acid is associated with abnormalities such as Coronary heart disease, abnormal fragmented structure, Arterial thrombosis and Subarachnoid Hemorrhage. The involved functions are known as Anabolism, Signal, Transcription, Genetic, Saturated and Regulation. Alpha-linolenic acid often locates in Blood, Body tissue, Plasma membrane, Hepatic and peroxisome. The associated genes with alpha-linolenic acid are FATE1 gene, volicitin, CYP2U1 gene, CYP1A2 gene and CYP2J2 gene. The related lipids are Fatty Acids, Dietary Fatty Acid, stearidonic acid and Fatty Acids, Nonesterified.
Cross Reference
Introduction
To understand associated biological information of alpha-linolenic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with alpha-linolenic acid?
alpha-linolenic acid is suspected in Coronary heart disease, Arterial thrombosis, Subarachnoid Hemorrhage and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with alpha-linolenic acid
PubChem Associated disorders and diseases
What pathways are associated with alpha-linolenic acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with alpha-linolenic acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with alpha-linolenic acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with alpha-linolenic acid?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with alpha-linolenic acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with alpha-linolenic acid?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with alpha-linolenic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Seppänen-Laakso T et al. | Replacement of margarine on bread by rapeseed and olive oils: effects on plasma fatty acid composition and serum cholesterol. | 1993 | Ann. Nutr. Metab. | pmid:8105749 |
| Giovannucci E et al. | A prospective study of dietary fat and risk of prostate cancer. | 1993 | J. Natl. Cancer Inst. | pmid:8105097 |
| Spady DK | Regulatory effects of individual n-6 and n-3 polyunsaturated fatty acids on LDL transport in the rat. | 1993 | J. Lipid Res. | pmid:8105015 |
| Cunnane SC et al. | Low zinc intake increases apparent oxidation of linoleic and alpha-linolenic acids in the pregnant rat. | 1993 Mar-Apr | Can. J. Physiol. Pharmacol. | pmid:8104673 |
| Ikeda A and Sugano M | Interaction of dietary protein and alpha-linolenic acid on polyunsaturated fatty acid composition of liver microsomal phospholipids and eicosanoid production in streptozotocin-induced diabetic rats. | 1993 | Ann. Nutr. Metab. | pmid:8103979 |
| Javouhey-Donzel A et al. | Rat vitamin E status and heart lipid peroxidation: effect of dietary alpha-linolenic acid and marine n-3 fatty acids. | 1993 | Lipids | pmid:8102771 |
| Dinh TK et al. | Effect of age and alpha-linolenic acid deficiency on delta 6 desaturase activity and liver lipids in rats. | 1993 | Lipids | pmid:8102769 |
| Browse J et al. | Mutants of Arabidopsis deficient in the synthesis of alpha-linolenate. Biochemical and genetic characterization of the endoplasmic reticulum linoleoyl desaturase. | 1993 | J. Biol. Chem. | pmid:8102138 |
| Bourre JM et al. | Dietary alpha-linolenic acid at 1.3 g/kg maintains maximal docosahexaenoic acid concentration in brain, heart and liver of adult rats. | 1993 | J. Nutr. | pmid:8100576 |
| Shichiri G et al. | Polyunsaturated fatty acid metabolism and acetylated low density lipoprotein uptake in J774A.1 cells. | 1993 | Arch. Biochem. Biophys. | pmid:8099780 |
| Cunnane SC et al. | High alpha-linolenic acid flaxseed (Linum usitatissimum): some nutritional properties in humans. | 1993 | Br. J. Nutr. | pmid:8098222 |
| Cantrill RC et al. | Comparison of the metabolism of alpha-linolenic acid and its delta 6 desaturation product, stearidonic acid, in cultured NIH-3T3 cells. | 1993 | Lipids | pmid:8096621 |
| Ferrari-Iliou R et al. | In vitro photodynamic lipid peroxidation of total lipophilic extracts from leaves of bean plants. | 1993 | Biochim. Biophys. Acta | pmid:8094299 |
| Hanai T et al. | Comparison of prostanoids and their precursor fatty acids in human hepatocellular carcinoma and noncancerous reference tissues. | 1993 | J. Surg. Res. | pmid:8094103 |
| Nakashima Y et al. | Effect of a high linoleate and a high alpha-linolenate diet on general behavior and drug sensitivity in mice. | 1993 | J. Lipid Res. | pmid:8094090 |
| Bourre JM et al. | Function of dietary polyunsaturated fatty acids in the nervous system. | 1993 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:8093816 |
| Yang JG et al. | Determination of the contents of EPA and DHA and lipid constituents in main fresh water fishes in China. | 1994 | J. Tongji Med. Univ. | pmid:7966518 |
| Gibson RA et al. | Ratios of linoleic acid to alpha-linolenic acid in formulas for term infants. | 1994 | J. Pediatr. | pmid:7965453 |
| Macrì F et al. | Lipoxygenase activity associated to isolated soybean plasma membranes. | 1994 | Biochim. Biophys. Acta | pmid:7947991 |
| Oe H et al. | Calcium overload and cardiac myocyte cell damage induced by arachidonate lipoxygenation. | 1994 | Am. J. Physiol. | pmid:7943384 |