alpha-linolenic acid

Alpha-linolenic acid is a lipid of Fatty Acyls (FA) class. Alpha-linolenic acid is associated with abnormalities such as Coronary heart disease, abnormal fragmented structure, Arterial thrombosis and Subarachnoid Hemorrhage. The involved functions are known as Anabolism, Signal, Transcription, Genetic, Saturated and Regulation. Alpha-linolenic acid often locates in Blood, Body tissue, Plasma membrane, Hepatic and peroxisome. The associated genes with alpha-linolenic acid are FATE1 gene, volicitin, CYP2U1 gene, CYP1A2 gene and CYP2J2 gene. The related lipids are Fatty Acids, Dietary Fatty Acid, stearidonic acid and Fatty Acids, Nonesterified.

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Introduction

To understand associated biological information of alpha-linolenic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with alpha-linolenic acid?

alpha-linolenic acid is suspected in Coronary heart disease, Arterial thrombosis, Subarachnoid Hemorrhage and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with alpha-linolenic acid

MeSH term MeSH ID Detail
Diabetic Angiopathies D003925 20 associated lipids
Diabetic Nephropathies D003928 39 associated lipids
Edema D004487 152 associated lipids
Encephalomyelitis, Autoimmune, Experimental D004681 26 associated lipids
Endomyocardial Fibrosis D004719 4 associated lipids
Epilepsy D004827 35 associated lipids
Mental Fatigue D005222 3 associated lipids
Fatty Liver D005234 48 associated lipids
Hearing Loss, High-Frequency D006316 1 associated lipids
Heart Failure D006333 36 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with alpha-linolenic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with alpha-linolenic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with alpha-linolenic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with alpha-linolenic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with alpha-linolenic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with alpha-linolenic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with alpha-linolenic acid

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Authors Title Published Journal PubMed Link
Schuchardt JP et al. Comparison of free serum oxylipin concentrations in hyper- vs. normolipidemic men. 2013 Prostaglandins Leukot. Essent. Fatty Acids pmid:23694766
Burdge GC and Wootton SA Conversion of alpha-linolenic acid to palmitic, palmitoleic, stearic and oleic acids in men and women. 2003 Prostaglandins Leukot. Essent. Fatty Acids pmid:12907139
Vancassel S et al. Plasma fatty acid levels in autistic children. 2001 Prostaglandins Leukot. Essent. Fatty Acids pmid:11487301
Hurst S et al. Dietary fatty acids and arthritis. 2010 Apr-Jun Prostaglandins Leukot. Essent. Fatty Acids pmid:20189789
Tocher DR and Dick JR Effects of essential fatty acid deficiency and supplementation with docosahexaenoic acid (DHA; 22:6n-3) on cellular fatty acid compositions and fatty acyl desaturation in a cell culture model. 2001 Prostaglandins Leukot. Essent. Fatty Acids pmid:11161581
Kartikasari LR et al. Dietary alpha-linolenic acid enhances omega-3 long chain polyunsaturated fatty acid levels in chicken tissues. 2012 Oct-Nov Prostaglandins Leukot. Essent. Fatty Acids pmid:22925778
Harland DR et al. Acute effects of prostaglandin E1 and E2 on vascular reactivity and blood flow in situ in the chick chorioallantoic membrane. 2012 Aug-Sep Prostaglandins Leukot. Essent. Fatty Acids pmid:22858445
Muñoz SF et al. Protective capability of dietary Zizyphus mistol seed oil, rich in 18:3, n-3, on the development of two murine mammary gland adenocarcinomas with high or low metastatic potential. 1995 Prostaglandins Leukot. Essent. Fatty Acids pmid:7480075
Charnock JS Gamma-linolenic acid provides additional protection against ventricular fibrillation in aged rats fed linoleic acid rich diets. 2000 Prostaglandins Leukot. Essent. Fatty Acids pmid:10780878
Brenna JT et al. alpha-Linolenic acid supplementation and conversion to n-3 long-chain polyunsaturated fatty acids in humans. 2009 Feb-Mar Prostaglandins Leukot. Essent. Fatty Acids pmid:19269799