alpha-linolenic acid

Alpha-linolenic acid is a lipid of Fatty Acyls (FA) class. Alpha-linolenic acid is associated with abnormalities such as Coronary heart disease, abnormal fragmented structure, Arterial thrombosis and Subarachnoid Hemorrhage. The involved functions are known as Anabolism, Signal, Transcription, Genetic, Saturated and Regulation. Alpha-linolenic acid often locates in Blood, Body tissue, Plasma membrane, Hepatic and peroxisome. The associated genes with alpha-linolenic acid are FATE1 gene, volicitin, CYP2U1 gene, CYP1A2 gene and CYP2J2 gene. The related lipids are Fatty Acids, Dietary Fatty Acid, stearidonic acid and Fatty Acids, Nonesterified.

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Introduction

To understand associated biological information of alpha-linolenic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with alpha-linolenic acid?

alpha-linolenic acid is suspected in Coronary heart disease, Arterial thrombosis, Subarachnoid Hemorrhage and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with alpha-linolenic acid

MeSH term MeSH ID Detail
Metabolism, Inborn Errors D008661 46 associated lipids
Hypercholesterolemia D006937 91 associated lipids
Thrombosis D013927 49 associated lipids
Myocardial Infarction D009203 21 associated lipids
Adrenoleukodystrophy D000326 29 associated lipids
Urinary Bladder Neoplasms D001749 7 associated lipids
Prostatic Hyperplasia D011470 20 associated lipids
Arteriosclerosis D001161 86 associated lipids
Neuroblastoma D009447 66 associated lipids
Carcinoma, Hepatocellular D006528 140 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with alpha-linolenic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with alpha-linolenic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with alpha-linolenic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with alpha-linolenic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with alpha-linolenic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with alpha-linolenic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with alpha-linolenic acid

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Authors Title Published Journal PubMed Link
Crawford M et al. Role of plant-derived omega-3 fatty acids in human nutrition. 2000 Ann. Nutr. Metab. pmid:11146334
Utsunomiya T et al. Correspondence re: M. Kondo et al., Increased expression of COX-2 in nontumor liver tissue is associated with shorter disease-free survival in patients with hepatocellular carcinoma. Clin. Cancer Res., 5: 4005-4012, 1999. 2000 Clin. Cancer Res. pmid:11156258
Cho E et al. Prospective study of dietary fat and the risk of age-related macular degeneration. 2001 Am. J. Clin. Nutr. pmid:11157315
Tocher DR and Dick JR Effects of essential fatty acid deficiency and supplementation with docosahexaenoic acid (DHA; 22:6n-3) on cellular fatty acid compositions and fatty acyl desaturation in a cell culture model. 2001 Prostaglandins Leukot. Essent. Fatty Acids pmid:11161581
Soppela P and Nieminen M The effect of wintertime undernutrition on the fatty acid composition of leg bone marrow fats in reindeer (Rangifer tarandus tarandus L.). 2001 Comp. Biochem. Physiol. B, Biochem. Mol. Biol. pmid:11163305
Wiesenfeld PW et al. Effect of long-chain fatty acids in the culture medium on fatty acid composition of WEHI-3 and J774A.1 cells. 2001 Comp. Biochem. Physiol. B, Biochem. Mol. Biol. pmid:11163311
Dikalov SI and Mason RP Spin trapping of polyunsaturated fatty acid-derived peroxyl radicals: reassignment to alkoxyl radical adducts. 2001 Free Radic. Biol. Med. pmid:11163536
Kaushik N and Agnihotri A GLC analysis of Indian rapeseed-mustard to study the variability of fatty acid composition. 2000 Biochem. Soc. Trans. pmid:11171132
Dobson G Leaf lipids of Ribes nigrum: a plant containing 16:3, alpha-18:3, gamma-18:3 and 18:4 fatty acids. 2000 Biochem. Soc. Trans. pmid:11171133
Grechkin AN et al. Lipoxygenase pathway in tulip: biosynthesis of ketols. 2000 Biochem. Soc. Trans. pmid:11171230