alpha-linolenic acid

Alpha-linolenic acid is a lipid of Fatty Acyls (FA) class. Alpha-linolenic acid is associated with abnormalities such as Coronary heart disease, abnormal fragmented structure, Arterial thrombosis and Subarachnoid Hemorrhage. The involved functions are known as Anabolism, Signal, Transcription, Genetic, Saturated and Regulation. Alpha-linolenic acid often locates in Blood, Body tissue, Plasma membrane, Hepatic and peroxisome. The associated genes with alpha-linolenic acid are FATE1 gene, volicitin, CYP2U1 gene, CYP1A2 gene and CYP2J2 gene. The related lipids are Fatty Acids, Dietary Fatty Acid, stearidonic acid and Fatty Acids, Nonesterified.

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Introduction

To understand associated biological information of alpha-linolenic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with alpha-linolenic acid?

alpha-linolenic acid is suspected in Coronary heart disease, Arterial thrombosis, Subarachnoid Hemorrhage and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with alpha-linolenic acid

MeSH term MeSH ID Detail
Liver Diseases D008107 31 associated lipids
Stroke D020521 32 associated lipids
Neurotoxicity Syndromes D020258 34 associated lipids
Infarction, Middle Cerebral Artery D020244 35 associated lipids
Epilepsy D004827 35 associated lipids
Heart Failure D006333 36 associated lipids
Zellweger Syndrome D015211 39 associated lipids
Diabetic Nephropathies D003928 39 associated lipids
Adenoma D000236 40 associated lipids
Arthritis D001168 41 associated lipids
Hypersensitivity, Delayed D006968 43 associated lipids
Metabolic Syndrome D024821 44 associated lipids
Metabolism, Inborn Errors D008661 46 associated lipids
Coronary Artery Disease D003324 47 associated lipids
Precancerous Conditions D011230 48 associated lipids
Fatty Liver D005234 48 associated lipids
Thrombosis D013927 49 associated lipids
Diabetes Mellitus, Type 1 D003922 56 associated lipids
Pain D010146 64 associated lipids
Cystic Fibrosis D003550 65 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with alpha-linolenic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with alpha-linolenic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with alpha-linolenic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with alpha-linolenic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with alpha-linolenic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with alpha-linolenic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with alpha-linolenic acid

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Authors Title Published Journal PubMed Link
Crawford M Placental delivery of arachidonic and docosahexaenoic acids: implications for the lipid nutrition of preterm infants. 2000 Am. J. Clin. Nutr. pmid:10617983
Auestad N and Innis SM Dietary n-3 fatty acid restriction during gestation in rats: neuronal cell body and growth-cone fatty acids. 2000 Am. J. Clin. Nutr. pmid:10617988
Dutta-Roy AK Transport mechanisms for long-chain polyunsaturated fatty acids in the human placenta. 2000 Am. J. Clin. Nutr. pmid:10617989
James MJ et al. Dietary polyunsaturated fatty acids and inflammatory mediator production. 2000 Am. J. Clin. Nutr. pmid:10617994
Horrobin DF Essential fatty acid metabolism and its modification in atopic eczema. 2000 Am. J. Clin. Nutr. pmid:10617999
Gibson RA Long-chain polyunsaturated fatty acids and infant development. 1999 Lancet pmid:10622289
Sugihara N et al. Anti- and pro-oxidative effects of flavonoids on metal-induced lipid hydroperoxide-dependent lipid peroxidation in cultured hepatocytes loaded with alpha-linolenic acid. 1999 Free Radic. Biol. Med. pmid:10641726
Oriani G et al. Effects of intramuscular injection of alpha-tocopheryl acetate on fatty acid profile in lamb liver. 1999 Int J Vitam Nutr Res pmid:10642895
Wensing AG et al. Effects of dietary n-3 polyunsaturated fatty acids from plant and marine origin on platelet aggregation in healthy elderly subjects. 1999 Br. J. Nutr. pmid:10655965
de Deckere EA et al. Effects of conjugated linoleic acid (CLA) isomers on lipid levels and peroxisome proliferation in the hamster. 1999 Br. J. Nutr. pmid:10655980