alpha-linolenic acid

Alpha-linolenic acid is a lipid of Fatty Acyls (FA) class. Alpha-linolenic acid is associated with abnormalities such as Coronary heart disease, abnormal fragmented structure, Arterial thrombosis and Subarachnoid Hemorrhage. The involved functions are known as Anabolism, Signal, Transcription, Genetic, Saturated and Regulation. Alpha-linolenic acid often locates in Blood, Body tissue, Plasma membrane, Hepatic and peroxisome. The associated genes with alpha-linolenic acid are FATE1 gene, volicitin, CYP2U1 gene, CYP1A2 gene and CYP2J2 gene. The related lipids are Fatty Acids, Dietary Fatty Acid, stearidonic acid and Fatty Acids, Nonesterified.

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Introduction

To understand associated biological information of alpha-linolenic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with alpha-linolenic acid?

alpha-linolenic acid is suspected in Coronary heart disease, Arterial thrombosis, Subarachnoid Hemorrhage and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with alpha-linolenic acid

MeSH term MeSH ID Detail
Ventricular Fibrillation D014693 16 associated lipids
Vitamin E Deficiency D014811 29 associated lipids
Colorectal Neoplasms D015179 10 associated lipids
Zellweger Syndrome D015211 39 associated lipids
Weight Gain D015430 101 associated lipids
Torsades de Pointes D016171 2 associated lipids
Death, Sudden, Cardiac D016757 12 associated lipids
Malaria, Falciparum D016778 22 associated lipids
Tachycardia, Ventricular D017180 9 associated lipids
Community-Acquired Infections D017714 8 associated lipids
Carcinoma, Ductal, Breast D018270 19 associated lipids
Depression, Postpartum D019052 3 associated lipids
Aging, Premature D019588 1 associated lipids
Infarction, Middle Cerebral Artery D020244 35 associated lipids
Neurotoxicity Syndromes D020258 34 associated lipids
Stroke D020521 32 associated lipids
Spinal Cord Ischemia D020760 2 associated lipids
Dyskinesias D020820 3 associated lipids
Metabolic Syndrome D024821 44 associated lipids
Vitamin B 6 Deficiency D026681 10 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with alpha-linolenic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with alpha-linolenic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with alpha-linolenic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with alpha-linolenic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with alpha-linolenic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with alpha-linolenic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with alpha-linolenic acid

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Per page 10 20 50 100 | Total 2471
Authors Title Published Journal PubMed Link
Guo Q et al. Highly sensitive method for the quantification of trans-linolenic acid isomers in trilinolenin of edible oils using an ionic liquid capillary column. 2017 J. Sci. Food Agric. pmid:28369919
Burak C et al. Effects of the flavonol quercetin and α-linolenic acid on n-3 PUFA status in metabolically healthy men and women: a randomised, double-blinded, placebo-controlled, crossover trial. 2017 Br. J. Nutr. pmid:28366181
Yadav S et al. Comparative efficacy of alpha-linolenic acid and gamma-linolenic acid to attenuate valproic acid-induced autism-like features. 2017 J. Physiol. Biochem. pmid:27878518
Bentrad N et al. Identification and evaluation of antibacterial agents present in lipophilic fractions isolated from sub-products of Phoenix dactilyfera. 2017 Nat. Prod. Res. pmid:28403631
Leroy C et al. Fatty acid-binding protein3 expression in BeWo cells, a human placental choriocarcinoma cell line. 2017 Prostaglandins Leukot. Essent. Fatty Acids pmid:28515017
Matravadia S et al. LA and ALA prevent glucose intolerance in obese male rats without reducing reactive lipid content, but cause tissue-specific changes in fatty acid composition. 2016 Am. J. Physiol. Regul. Integr. Comp. Physiol. pmid:26764053
López-Luna P et al. Fate of orally administered radioactive fatty acids in the late-pregnant rat. 2016 Am. J. Physiol. Endocrinol. Metab. pmid:26714850
Park HG et al. Palmitic acid (16:0) competes with omega-6 linoleic and omega-3 ɑ-linolenic acids for FADS2 mediated Δ6-desaturation. 2016 Biochim. Biophys. Acta pmid:26597785
Reddy YS et al. Study on Synthesis, Characterization and Antiproliferative Activity of Novel Diisopropylphenyl Esters of Selected Fatty Acids. 2016 J Oleo Sci pmid:26666272
Masoko P et al. Isolation of alpha-linolenic acid from Sutherlandia frutescens and its inhibition of Mycobacterium tuberculosis' shikimate kinase enzyme. 2016 BMC Complement Altern Med pmid:27639973
Devassy JG et al. Omega-3 Polyunsaturated Fatty Acids and Oxylipins in Neuroinflammation and Management of Alzheimer Disease. 2016 Adv Nutr pmid:27633106
Nuez-Ortín WG et al. Preliminary Validation of a High Docosahexaenoic Acid (DHA) and -Linolenic Acid (ALA) Dietary Oil Blend: Tissue Fatty Acid Composition and Liver Proteome Response in Atlantic Salmon (Salmo salar) Smolts. 2016 PLoS ONE pmid:27556399
Luo T et al. Consumption of Walnuts in Combination with Other Whole Foods Produces Physiologic, Metabolic, and Gene Expression Changes in Obese C57BL/6J High-Fat-Fed Male Mice. 2016 J. Nutr. pmid:27489005
Ando Y et al. Alpha Linolenic Acid-enriched Diacylglycerol Enhances Postprandial Fat Oxidation in Healthy Subjects: A Randomized Double-blind Controlled Trail. 2016 J Oleo Sci pmid:27430386
Shi H et al. Application of a delta-6 desaturase with α-linolenic acid preference on eicosapentaenoic acid production in Mortierella alpina. 2016 Microb. Cell Fact. pmid:27364006
Del Gobbo LC et al. ω-3 Polyunsaturated Fatty Acid Biomarkers and Coronary Heart Disease: Pooling Project of 19 Cohort Studies. 2016 JAMA Intern Med pmid:27357102
Venäläinen TM et al. Effect of a 2-y dietary and physical activity intervention on plasma fatty acid composition and estimated desaturase and elongase activities in children: the Physical Activity and Nutrition in Children Study. 2016 Am. J. Clin. Nutr. pmid:27581473
Sakayori N et al. Maternal Nutritional Imbalance between Linoleic Acid and Alpha-Linolenic Acid Increases Offspring's Anxious Behavior with a Sex-Dependent Manner in Mice. 2016 Tohoku J. Exp. Med. pmid:27558477
Mata-Pérez C et al. Nitro-Fatty Acids in Plant Signaling: Nitro-Linolenic Acid Induces the Molecular Chaperone Network in Arabidopsis. 2016 Plant Physiol. pmid:26628746
Sun Y et al. Plasma α-Linolenic and Long-Chain ω-3 Fatty Acids Are Associated with a Lower Risk of Acute Myocardial Infarction in Singapore Chinese Adults. 2016 J. Nutr. pmid:26609174