alpha-linolenic acid

Alpha-linolenic acid is a lipid of Fatty Acyls (FA) class. Alpha-linolenic acid is associated with abnormalities such as Coronary heart disease, abnormal fragmented structure, Arterial thrombosis and Subarachnoid Hemorrhage. The involved functions are known as Anabolism, Signal, Transcription, Genetic, Saturated and Regulation. Alpha-linolenic acid often locates in Blood, Body tissue, Plasma membrane, Hepatic and peroxisome. The associated genes with alpha-linolenic acid are FATE1 gene, volicitin, CYP2U1 gene, CYP1A2 gene and CYP2J2 gene. The related lipids are Fatty Acids, Dietary Fatty Acid, stearidonic acid and Fatty Acids, Nonesterified.

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Introduction

To understand associated biological information of alpha-linolenic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with alpha-linolenic acid?

alpha-linolenic acid is suspected in Coronary heart disease, Arterial thrombosis, Subarachnoid Hemorrhage and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with alpha-linolenic acid

MeSH term MeSH ID Detail
Tachycardia, Ventricular D017180 9 associated lipids
Long QT Syndrome D008133 10 associated lipids
Retinal Degeneration D012162 9 associated lipids
Malaria, Falciparum D016778 22 associated lipids
Retinoblastoma D012175 12 associated lipids
Hyperlipidemia, Familial Combined D006950 9 associated lipids
Neurotoxicity Syndromes D020258 34 associated lipids
Irritable Bowel Syndrome D043183 8 associated lipids
Community-Acquired Infections D017714 8 associated lipids
Sebaceous Gland Neoplasms D012626 2 associated lipids
Hearing Loss, High-Frequency D006316 1 associated lipids
Night Blindness D009755 1 associated lipids
Otorhinolaryngologic Neoplasms D010039 2 associated lipids
Spinal Cord Ischemia D020760 2 associated lipids
Mental Fatigue D005222 3 associated lipids
Depression, Postpartum D019052 3 associated lipids
Torsades de Pointes D016171 2 associated lipids
Dyskinesias D020820 3 associated lipids
Aging, Premature D019588 1 associated lipids
Insect Bites and Stings D007299 4 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with alpha-linolenic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with alpha-linolenic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with alpha-linolenic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with alpha-linolenic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with alpha-linolenic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with alpha-linolenic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with alpha-linolenic acid

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Authors Title Published Journal PubMed Link
Li T et al. Defense priming by non-jasmonate producing fatty acids in maize (Zea mays). 2016 Plant Signal Behav pmid:27763804
Kjær MA et al. Regulation of the Omega-3 Fatty Acid Biosynthetic Pathway in Atlantic Salmon Hepatocytes. 2016 PLoS ONE pmid:27973547
Cao X et al. Transcriptional Responses and Gentiopicroside Biosynthesis in Methyl Jasmonate-Treated Gentiana macrophylla Seedlings. 2016 PLoS ONE pmid:27851826
Wolters M et al. Associations of Whole Blood n-3 and n-6 Polyunsaturated Fatty Acids with Blood Pressure in Children and Adolescents - Results from the IDEFICS/I.Family Cohort. 2016 PLoS ONE pmid:27806134
Demorest ZL et al. Direct stacking of sequence-specific nuclease-induced mutations to produce high oleic and low linolenic soybean oil. 2016 BMC Plant Biol. pmid:27733139
Carotenuto F et al. Dietary Flaxseed Mitigates Impaired Skeletal Muscle Regeneration: in Vivo, in Vitro and in Silico Studies. 2016 Int J Med Sci pmid:26941581
Dote S et al. Effects of Triacylglycerol Molecular Species on the Oxidation Behavior of Oils Containing α-Linolenic Acid. 2016 J Oleo Sci pmid:26935948
Heskey CE et al. Adipose tissue α-linolenic acid is inversely associated with insulin resistance in adults. 2016 Am. J. Clin. Nutr. pmid:26912497
Zhao N et al. α-Linolenic acid increases the G0/G1 switch gene 2 mRNA expression in peripheral blood mononuclear cells from obese patients: a pilot study. 2016 Lipids Health Dis pmid:26912161
Taha AY et al. Threshold changes in rat brain docosahexaenoic acid incorporation and concentration following graded reductions in dietary alpha-linolenic acid. 2016 Prostaglandins Leukot. Essent. Fatty Acids pmid:26869088