Alpha-linolenic acid is a lipid of Fatty Acyls (FA) class. Alpha-linolenic acid is associated with abnormalities such as Coronary heart disease, abnormal fragmented structure, Arterial thrombosis and Subarachnoid Hemorrhage. The involved functions are known as Anabolism, Signal, Transcription, Genetic, Saturated and Regulation. Alpha-linolenic acid often locates in Blood, Body tissue, Plasma membrane, Hepatic and peroxisome. The associated genes with alpha-linolenic acid are FATE1 gene, volicitin, CYP2U1 gene, CYP1A2 gene and CYP2J2 gene. The related lipids are Fatty Acids, Dietary Fatty Acid, stearidonic acid and Fatty Acids, Nonesterified.
To understand associated biological information of alpha-linolenic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
alpha-linolenic acid is suspected in Coronary heart disease, Arterial thrombosis, Subarachnoid Hemorrhage and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
---|
We collected disease MeSH terms mapped to the references associated with alpha-linolenic acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
---|
Function | Cross reference | Weighted score | Related literatures |
---|
Lipid concept | Cross reference | Weighted score | Related literatures |
---|
Gene | Cross reference | Weighted score | Related literatures |
---|
There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
---|---|---|---|---|
Monge-Rojas R et al. | Changes in dietary intake and food sources of saturated and cis and trans unsaturated fatty acids in Costa Rican adolescents: 1996 versus 2006. | 2013 | Nutrition | pmid:23298971 |
Molkentin J | Applicability of organic milk indicators to the authentication of processed products. | 2013 | Food Chem | pmid:23199986 |
Ulas T et al. | Does α-lipoic acid treatment play a role on oxidative stress and insulin resistance in overweight/obese patients? | 2013 | Int. J. Cardiol. | pmid:23200266 |
Zhao ML et al. | Enzymatic production of zero-trans plastic fat rich in α-linolenic acid and medium-chain fatty acids from highly hydrogenated soybean oil, Cinnamomum camphora seed oil, and perilla oil by lipozyme TL IM. | 2013 | J. Agric. Food Chem. | pmid:23350869 |
Nozue T et al. | Effects of statins on serum n-3 to n-6 polyunsaturated fatty acid ratios in patients with coronary artery disease. | 2013 | J. Cardiovasc. Pharmacol. Ther. | pmid:23324995 |
Cedernaes J et al. | Adipose tissue stearoyl-CoA desaturase 1 index is increased and linoleic acid is decreased in obesity-prone rats fed a high-fat diet. | 2013 | Lipids Health Dis | pmid:23298201 |
Kastner DW and Van Wagoner DR | Diet and atrial fibrillation: does α-linolenic acid, a plant derived essential fatty acid, have an impact? | 2013 | J Am Heart Assoc | pmid:23525415 |
Fretts AM et al. | Associations of plasma phospholipid and dietary alpha linolenic acid with incident atrial fibrillation in older adults: the Cardiovascular Health Study. | 2013 | J Am Heart Assoc | pmid:23525429 |
Kälber T et al. | Effect of feeding buckwheat and chicory silages on fatty acid profile and cheese-making properties of milk from dairy cows. | 2013 | J. Dairy Res. | pmid:23253429 |
Monteiro J et al. | Oils rich in α-linolenic acid independently protect against characteristics of fatty liver disease in the Δ6-desaturase null mouse. | 2013 | Can. J. Physiol. Pharmacol. | pmid:23746194 |
Gillingham LG et al. | Dietary oils and FADS1-FADS2 genetic variants modulate [13C]α-linolenic acid metabolism and plasma fatty acid composition. | 2013 | Am. J. Clin. Nutr. | pmid:23221573 |
Liu M et al. | Characterization and biological effects of di-hydroxylated compounds deriving from the lipoxygenation of ALA. | 2013 | J. Lipid Res. | pmid:23740966 |
Kim Y et al. | Synergism of α-linolenic acid, conjugated linoleic acid and calcium in decreasing adipocyte and increasing osteoblast cell growth. | 2013 | Lipids | pmid:23757205 |
Lai YH et al. | Association of dietary omega-3 fatty acids with prevalence of metabolic syndrome: the National Heart, Lung, and Blood Institute Family Heart Study. | 2013 | Clin Nutr | pmid:23711994 |
Gage SH et al. | Functionalization of monodisperse iron oxide NPs and their properties as magnetically recoverable catalysts. | 2013 | Langmuir | pmid:23234434 |
Lohner S et al. | Gender differences in the long-chain polyunsaturated fatty acid status: systematic review of 51 publications. | 2013 | Ann. Nutr. Metab. | pmid:23327902 |
Carey AN et al. | The ability of walnut extract and fatty acids to protect against the deleterious effects of oxidative stress and inflammation in hippocampal cells. | 2013 | Nutr Neurosci | pmid:23321679 |
Coles L et al. | A model to predict the ATP equivalents of macronutrients absorbed from food. | 2013 | Food Funct | pmid:23233079 |
Shen JH et al. | Effect of α-linolenic acid on streptozotocin-induced diabetic retinopathy indices in vivo. | 2013 | Arch. Med. Res. | pmid:24120388 |
Végner L et al. | Experimental confirmation of new drug-target interactions predicted by Drug Profile Matching. | 2013 | J. Med. Chem. | pmid:24088053 |
Yang Z and Huffman SL | Modelling linoleic acid and α-linolenic acid requirements for infants and young children in developing countries. | 2013 | Matern Child Nutr | pmid:23167585 |
Alhazzaa R et al. | Bioconversion of α-linolenic acid into n-3 long-chain polyunsaturated fatty acid in hepatocytes and ad hoc cell culture optimisation. | 2013 | PLoS ONE | pmid:24040040 |
Botsoglou E et al. | Olive leaves (Olea europea L.) and α-tocopheryl acetate as feed antioxidants for improving the oxidative stability of α-linolenic acid-enriched eggs. | 2013 | J Anim Physiol Anim Nutr (Berl) | pmid:22716021 |
Kartikasari LR et al. | Dietary alpha-linolenic acid enhances omega-3 long chain polyunsaturated fatty acid levels in chicken tissues. | 2012 Oct-Nov | Prostaglandins Leukot. Essent. Fatty Acids | pmid:22925778 |
Tsuzuki W | Inconsistencies in a highly polar capillary gas chromatography column and necessity of column performance checks for trans fatty acid measurement. | 2012 Nov-Dec | J AOAC Int | pmid:23451392 |
Hofacer R et al. | Omega-3 fatty acid deficiency increases stearoyl-CoA desaturase expression and activity indices in rat liver: positive association with non-fasting plasma triglyceride levels. | 2012 Jan-Feb | Prostaglandins Leukot. Essent. Fatty Acids | pmid:22047910 |
Harland DR et al. | Acute effects of prostaglandin E1 and E2 on vascular reactivity and blood flow in situ in the chick chorioallantoic membrane. | 2012 Aug-Sep | Prostaglandins Leukot. Essent. Fatty Acids | pmid:22858445 |
Sugasini D and Lokesh BR | Uptake of α-linolenic acid and its conversion to long chain omega-3 fatty acids in rats fed microemulsions of linseed oil. | 2012 | Lipids | pmid:23104428 |
Fang XL et al. | Roles of α-linolenic acid on IGF-I secretion and GH/IGF system gene expression in porcine primary hepatocytes. | 2012 | Mol. Biol. Rep. | pmid:23053988 |
He ML et al. | Triticale dried distillers' grain increases alpha-linolenic acid in subcutaneous fat of beef cattle fed oilseeds. | 2012 | Lipids | pmid:23054550 |
Garcia CV et al. | Characterisation of bound volatile compounds of a low flavour kiwifruit species: Actinidia eriantha. | 2012 | Food Chem | pmid:23107675 |
Saha SS et al. | Synergistic effect of conjugated linolenic acid isomers against induced oxidative stress, inflammation and erythrocyte membrane disintegrity in rat model. | 2012 | Biochim. Biophys. Acta | pmid:22967758 |
de Batlle J et al. | Association between Ω3 and Ω6 fatty acid intakes and serum inflammatory markers in COPD. | 2012 | J. Nutr. Biochem. | pmid:21889886 |
Sun T et al. | Meat fatty acid and cholesterol level of free-range broilers fed on grasshoppers on alpine rangeland in the Tibetan Plateau. | 2012 | J. Sci. Food Agric. | pmid:22318921 |
Deckelbaum RJ and Torrejon C | The omega-3 fatty acid nutritional landscape: health benefits and sources. | 2012 | J. Nutr. | pmid:22323763 |
Larsen MK et al. | Fatty acid, tocopherol and carotenoid content in herbage and milk affected by sward composition and season of grazing. | 2012 | J. Sci. Food Agric. | pmid:22337263 |
Hughes BH et al. | Oxidative stability and consumer acceptance of fish oil fortified nutrition bars. | 2012 | J. Food Sci. | pmid:22957916 |
Aliani M et al. | Effect of flax addition on the flavor profile and acceptability of bagels. | 2012 | J. Food Sci. | pmid:22260132 |
Janssen S et al. | Sensing of fatty acids for octanoylation of ghrelin involves a gustatory G-protein. | 2012 | PLoS ONE | pmid:22768248 |
Zhang G et al. | Erythrocyte n-3 fatty acids and metabolic syndrome in middle-aged and older Chinese. | 2012 | J. Clin. Endocrinol. Metab. | pmid:22456621 |
Ishida Y et al. | Validation of thermally assisted hydrolysis and methylation-gas chromatography using a vertical microfurnace pyrolyzer for the compositional analysis of Fatty Acid components in microalgae. | 2012 | J. Agric. Food Chem. | pmid:22458968 |
Mirmiran P et al. | Association between interaction and ratio of ω-3 and ω-6 polyunsaturated fatty acid and the metabolic syndrome in adults. | 2012 | Nutrition | pmid:22459553 |
Maqbool A et al. | Relation between dietary fat intake type and serum fatty acid status in children with cystic fibrosis. | 2012 | J. Pediatr. Gastroenterol. Nutr. | pmid:22699835 |
Du Q et al. | Dairy fat blends high in α-linolenic acid are superior to n-3 fatty-acid-enriched palm oil blends for increasing DHA levels in the brains of young rats. | 2012 | J. Nutr. Biochem. | pmid:22445803 |
Miyake Y et al. | Dietary meat and fat intake and prevalence of rhinoconjunctivitis in pregnant Japanese women: baseline data from the Kyushu Okinawa Maternal and Child Health Study. | 2012 | Nutr J | pmid:22449171 |
Fatima T et al. | Fatty acid composition of developing sea buckthorn (Hippophae rhamnoides L.) berry and the transcriptome of the mature seed. | 2012 | PLoS ONE | pmid:22558083 |
Longvah T et al. | Eri silkworm: a source of edible oil with a high content of α-linolenic acid and of significant nutritional value. | 2012 | J. Sci. Food Agric. | pmid:22290445 |
Monteiro J et al. | Menhaden oil, but not safflower or soybean oil, aids in restoring the polyunsaturated fatty acid profile in the novel delta-6-desaturase null mouse. | 2012 | Lipids Health Dis | pmid:22642787 |
Pan H et al. | Alpha-linolenic acid is a potent neuroprotective agent against soman-induced neuropathology. | 2012 | Neurotoxicology | pmid:22884490 |
Huan M et al. | In vivo anti-tumor activity of a new doxorubicin conjugate via α-linolenic acid. | 2012 | Biosci. Biotechnol. Biochem. | pmid:22878199 |