MeSH term | MeSH ID | Detail |
---|---|---|
Colonic Neoplasms | D003110 | 161 associated lipids |
Adenocarcinoma | D000230 | 166 associated lipids |
Lung Neoplasms | D008175 | 171 associated lipids |
Body Weight | D001835 | 333 associated lipids |
Alpha-linolenic acid is a lipid of Fatty Acyls (FA) class. Alpha-linolenic acid is associated with abnormalities such as Coronary heart disease, abnormal fragmented structure, Arterial thrombosis and Subarachnoid Hemorrhage. The involved functions are known as Anabolism, Signal, Transcription, Genetic, Saturated and Regulation. Alpha-linolenic acid often locates in Blood, Body tissue, Plasma membrane, Hepatic and peroxisome. The associated genes with alpha-linolenic acid are FATE1 gene, volicitin, CYP2U1 gene, CYP1A2 gene and CYP2J2 gene. The related lipids are Fatty Acids, Dietary Fatty Acid, stearidonic acid and Fatty Acids, Nonesterified.
To understand associated biological information of alpha-linolenic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
alpha-linolenic acid is suspected in Coronary heart disease, Arterial thrombosis, Subarachnoid Hemorrhage and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with alpha-linolenic acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Williard DE et al. | Production and release of docosahexaenoic acid by differentiated rat brain astrocytes. | 2001 | World Rev Nutr Diet | pmid:11935950 |
Cunnane SC | New developments in alpha-linolenate metabolism with emphasis on the importance of beta-oxidation and carbon recycling. | 2001 | World Rev Nutr Diet | pmid:11935952 |
Okuyama H et al. | alpha-linolenate-deficiency-induced alterations in brightness discrimination learning behavior and retinal function in rats. | 2001 | World Rev Nutr Diet | pmid:11935967 |
Renaud SC and Lanzmann-Petithory D | alpha-linolenic acid in the prevention of cardiovascular diseases. | 2001 | World Rev Nutr Diet | pmid:11935975 |
Voigt RG et al. | Relationship between omega3 long-chain polyunsaturated fatty acid status during early infancy and neurodevelopmental status at 1 year of age. | 2002 | J Hum Nutr Diet | pmid:11972740 |
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Dunbar BL and Bauer JE | Conversion of essential fatty acids by Delta 6-desaturase in dog liver microsomes. | 2002 | J. Nutr. | pmid:12042499 |
Zabrouskov V and Knowles NR | Lipid metabolism during aging of high-alpha-linolenate-phenotype potato tubers. | 2002 | Arch. Biochem. Biophys. | pmid:12051691 |
Suzuki R et al. | Effects of n-3 polyunsaturated fatty acids on dermatitis in NC/Nga mice. | 2002 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:12054914 |
Ishihara K et al. | Comparison of the effects of dietary alpha-linolenic, stearidonic, and eicosapentaenoic acids on production of inflammatory mediators in mice. | 2002 | Lipids | pmid:12056590 |
Haggarty P et al. | The effect of maternal smoking and ethanol on fatty acid transport by the human placenta. | 2002 | Br. J. Nutr. | pmid:12064333 |
Ximenes da Silva A et al. | Glucose transport and utilization are altered in the brain of rats deficient in n-3 polyunsaturated fatty acids. | 2002 | J. Neurochem. | pmid:12068080 |
Ward AT et al. | Bovine milk fatty acid profiles produced by feeding diets containing solin, flax and canola. | 2002 | J. Dairy Sci. | pmid:12086055 |
Robinson RS et al. | Effects of dietary polyunsaturated fatty acids on ovarian and uterine function in lactating dairy cows. | 2002 | Reproduction | pmid:12090925 |
Kimura Y | Carp oil or oleic acid, but not linoleic acid or linolenic acid, inhibits tumor growth and metastasis in Lewis lung carcinoma-bearing mice. | 2002 | J. Nutr. | pmid:12097695 |
Anwar F et al. | Analytical characterization of Salicornia bigelovii seed oil cultivated in Pakistan. | 2002 | J. Agric. Food Chem. | pmid:12105947 |
Hisha H et al. | Treatment of Shwachman syndrome by Japanese herbal medicine (Juzen-taiho-to): stimulatory effects of its fatty acids on hemopoiesis in patients. | 2002 | Stem Cells | pmid:12110700 |
Shinohara R et al. | Evaluation of antilipid peroxidative action of propolis ethanol extract. | 2002 | Phytother Res | pmid:12112290 |
Blée E | Impact of phyto-oxylipins in plant defense. | 2002 | Trends Plant Sci. | pmid:12119169 |
Schreck U et al. | Intraindividual comparison of two different skin care conceptions in patients undergoing radiotherapy of the head-and-neck region. Creme or powder? | 2002 | Strahlenther Onkol | pmid:12122788 |
Hansen RA et al. | Effects of dietary flaxseed oil supplementation on equine plasma fatty acid concentrations and whole blood platelet aggregation. | 2002 Jul-Aug | J. Vet. Intern. Med. | pmid:12141309 |
Jeffrey BG et al. | n-3 fatty acid deficiency alters recovery of the rod photoresponse in rhesus monkeys. | 2002 | Invest. Ophthalmol. Vis. Sci. | pmid:12147619 |
Akakabe Y et al. | Enantioselective formation of (R)-9-HPODE and (R)-9-HPOTrE in marine green alga Ulva conglobata. | 2002 | Bioorg. Med. Chem. | pmid:12150862 |
Ghebremeskel K et al. | Liver triacylglycerols and free fatty acids in streptozotocin-induced diabetic rats have atypical n-6 and n-3 pattern. | 2002 | Comp. Biochem. Physiol. C Toxicol. Pharmacol. | pmid:12161168 |
Pratt VC et al. | Alterations in lymphocyte function and relation to phospholipid composition after burn injury in humans. | 2002 | Crit. Care Med. | pmid:12163788 |
Kreider RB et al. | Effects of conjugated linoleic acid supplementation during resistance training on body composition, bone density, strength, and selected hematological markers. | 2002 | J Strength Cond Res | pmid:12173945 |
Kaup MT et al. | A role for diacylglycerol acyltransferase during leaf senescence. | 2002 | Plant Physiol. | pmid:12177474 |
Göbel C et al. | Oxylipin profiling in pathogen-infected potato leaves. | 2002 | Biochim. Biophys. Acta | pmid:12213493 |
Weiler HA and Fitzpatrick-Wong SC | Modulation of essential (n-6):(n-3) fatty acid ratios alters fatty acid status but not bone mass in piglets. | 2002 | J. Nutr. | pmid:12221227 |
Itoh S et al. | Synthesis of the (17R)- and (17S)-isomers of volicitin, an elicitor of plant volatiles contained in the oral secretion of the beet armyworm. | 2002 | Biosci. Biotechnol. Biochem. | pmid:12224650 |
Blank C et al. | Optimizing DHA levels in piglets by lowering the linoleic acid to alpha-linolenic acid ratio. | 2002 | J. Lipid Res. | pmid:12235186 |
Burdge GC et al. | Eicosapentaenoic and docosapentaenoic acids are the principal products of alpha-linolenic acid metabolism in young men*. | 2002 | Br. J. Nutr. | pmid:12323085 |
Burdge GC and Wootton SA | Conversion of alpha-linolenic acid to eicosapentaenoic, docosapentaenoic and docosahexaenoic acids in young women. | 2002 | Br. J. Nutr. | pmid:12323090 |
Baylin A et al. | Adipose tissue biomarkers of fatty acid intake. | 2002 | Am. J. Clin. Nutr. | pmid:12324287 |
Renaud SC and Lanzmann-Petithory D | The beneficial effect of alpha-linolenic acid in coronary artery disease is not questionable. | 2002 | Am. J. Clin. Nutr. | pmid:12324307 |
Itoh A et al. | Identification of a jasmonate-regulated allene oxide synthase that metabolizes 9-hydroperoxides of linoleic and linolenic acids. | 2002 | J. Biol. Chem. | pmid:12351632 |
Renaud S and Lanzmann-Petithory D | Dietary fats and coronary heart disease pathogenesis. | 2002 | Curr Atheroscler Rep | pmid:12361488 |
Mashek DG et al. | Metabolic fate of long-chain unsaturated fatty acids and their effects on palmitic acid metabolism and gluconeogenesis in bovine hepatocytes. | 2002 | J. Dairy Sci. | pmid:12362461 |
Korotkova M et al. | Leptin levels in rat offspring are modified by the ratio of linoleic to alpha-linolenic acid in the maternal diet. | 2002 | J. Lipid Res. | pmid:12364559 |
Parmentier HK et al. | Different sources of dietary n-6 polyunsaturated fatty acids and their effects on antibody responses in chickens. | 2002 | Br. Poult. Sci. | pmid:12365510 |
Murase T et al. | Dietary alpha-linolenic acid-rich diacylglycerols reduce body weight gain accompanying the stimulation of intestinal beta-oxidation and related gene expressions in C57BL/KsJ-db/db mice. | 2002 | J. Nutr. | pmid:12368389 |
Acar N et al. | Long-term intake of trans (n-3) polyunsaturated fatty acids reduces the b-wave amplitude of electroretinograms in rats. | 2002 | J. Nutr. | pmid:12368410 |
Karvonen HM et al. | Effect of alpha-linolenic acid-rich Camelina sativa oil on serum fatty acid composition and serum lipids in hypercholesterolemic subjects. | 2002 | Metab. Clin. Exp. | pmid:12370843 |
Acar N et al. | Modification of the monoaminergic neurotransmitters in frontal cortex and hippocampus by dietary trans alpha-linolenic acid in piglets. | 2002 | Neurosci. Lett. | pmid:12383930 |
Nishimura K et al. | Regulation of apoptosis through arachidonate cascade in mammalian cells. | 2002 Jul-Dec | Appl. Biochem. Biotechnol. | pmid:12396127 |
Petkova-Andonova M et al. | CYP92B1, A cytochrome P450, expressed in petunia flower buds, that catalyzes monooxidation of long-chain fatty acids. | 2002 | Biosci. Biotechnol. Biochem. | pmid:12400678 |