MeSH term | MeSH ID | Detail |
---|---|---|
Irritable Bowel Syndrome | D043183 | 8 associated lipids |
Overweight | D050177 | 11 associated lipids |
Atherosclerosis | D050197 | 85 associated lipids |
Carcinogenesis | D063646 | 3 associated lipids |
Alpha-linolenic acid is a lipid of Fatty Acyls (FA) class. Alpha-linolenic acid is associated with abnormalities such as Coronary heart disease, abnormal fragmented structure, Arterial thrombosis and Subarachnoid Hemorrhage. The involved functions are known as Anabolism, Signal, Transcription, Genetic, Saturated and Regulation. Alpha-linolenic acid often locates in Blood, Body tissue, Plasma membrane, Hepatic and peroxisome. The associated genes with alpha-linolenic acid are FATE1 gene, volicitin, CYP2U1 gene, CYP1A2 gene and CYP2J2 gene. The related lipids are Fatty Acids, Dietary Fatty Acid, stearidonic acid and Fatty Acids, Nonesterified.
To understand associated biological information of alpha-linolenic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
alpha-linolenic acid is suspected in Coronary heart disease, Arterial thrombosis, Subarachnoid Hemorrhage and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
---|
We collected disease MeSH terms mapped to the references associated with alpha-linolenic acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
---|
Function | Cross reference | Weighted score | Related literatures |
---|
Lipid concept | Cross reference | Weighted score | Related literatures |
---|
Gene | Cross reference | Weighted score | Related literatures |
---|
There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
---|---|---|---|---|
[Dietary management of lipid disorders. Plant oil protects hearts of diabetic patients]. | 2003 | MMW Fortschr Med | pmid:14655490 | |
Chuang SS et al. | CYP2U1, a novel human thymus- and brain-specific cytochrome P450, catalyzes omega- and (omega-1)-hydroxylation of fatty acids. | 2004 | J. Biol. Chem. | pmid:14660610 |
Pawlosky R et al. | n-3 fatty acid metabolism in women. | 2003 | Br. J. Nutr. | pmid:14667193 |
Djoussé L et al. | Dietary linolenic acid is inversely associated with plasma triacylglycerol: the National Heart, Lung, and Blood Institute Family Heart Study. | 2003 | Am. J. Clin. Nutr. | pmid:14668270 |
Bazinet RP et al. | Dietary alpha-linolenic acid increases the n-3 PUFA content of sow's milk and the tissues of the suckling piglet. | 2003 | Lipids | pmid:14669969 |
Hauswirth CB et al. | High omega-3 fatty acid content in alpine cheese: the basis for an alpine paradox. | 2004 | Circulation | pmid:14676141 |
Dunn JD et al. | Effects of flax supplementation and a combined trenbolone acetate and estradiol implant on circulating insulin-like growth factor-I and muscle insulin-like growth factor-I messenger RNA levels in beef cattle. | 2003 | J. Anim. Sci. | pmid:14677858 |
Spence JD et al. | The effect of flax seed cultivars with differing content of alpha-linolenic acid and lignans on responses to mental stress. | 2003 | J Am Coll Nutr | pmid:14684754 |
Truitt CL and Paré PW | In situ translocation of volicitin by beet armyworm larvae to maize and systemic immobility of the herbivore elicitor in planta. | 2004 | Planta | pmid:14685859 |
Fleshner N et al. | Dietary fat and prostate cancer. | 2004 | J. Urol. | pmid:14713748 |
Truitt CL et al. | A plasma membrane protein from Zea mays binds with the herbivore elicitor volicitin. | 2004 | Plant Cell | pmid:14729912 |
Yoshinaga N et al. | Specific incorporation of L-glutamine into volicitin in the regurgitant of Spodoptera litura. | 2003 | Biosci. Biotechnol. Biochem. | pmid:14730148 |
Cabrita AR et al. | Nitrogen supplementation of corn silages. 2. Assessing rumen function using fatty acid profiles of bovine milk. | 2003 | J. Dairy Sci. | pmid:14740840 |
Mutsvangwa T et al. | Short communication: Effects of a monensin premix on milk fatty acid content during subacute ruminal acidosis in dairy cows. | 2003 | J. Dairy Sci. | pmid:14740842 |
de Groot RH et al. | Effect of alpha-linolenic acid supplementation during pregnancy on maternal and neonatal polyunsaturated fatty acid status and pregnancy outcome. | 2004 | Am. J. Clin. Nutr. | pmid:14749231 |
Tsuzuki T et al. | Tumor growth suppression by alpha-eleostearic acid, a linolenic acid isomer with a conjugated triene system, via lipid peroxidation. | 2004 | Carcinogenesis | pmid:14963014 |
Del Castillo ML et al. | Fatty acid content and juice characteristics in black currant (Ribes nigrum L.) genotypes. | 2004 | J. Agric. Food Chem. | pmid:14969555 |
Agostoni C | The difficult balance between dietary polyunsaturated fatty acids. | 2003 | Acta Paediatr. | pmid:14971782 |
Thiombiano-Coulibaly N et al. | Seasonal and environmental effects on breast milk fatty acids in Burkina Faso and the need to improve the omega 3 PUFA content. | 2003 | Acta Paediatr. | pmid:14971787 |
Bloedon LT and Szapary PO | Flaxseed and cardiovascular risk. | 2004 | Nutr. Rev. | pmid:14995053 |
Walters D et al. | Antifungal activities of four fatty acids against plant pathogenic fungi. | 2004 | Mycopathologia | pmid:15008350 |
Lissak A et al. | Oxidative stress indices in seminal plasma, as measured by the thermochemiluminescence assay, correlate with sperm parameters. | 2004 | Fertil. Steril. | pmid:15019811 |
Gohlke H | [Prevention of coronary disease and sudden death by nutrition]. | 2004 | Z Kardiol | pmid:15021992 |
Colazo MG et al. | Fertility following fixed-time AI in CIDR-treated beef heifers given GnRH or estradiol cypionate and fed diets supplemented with flax seed or sunflower seed. | 2004 | Theriogenology | pmid:15036999 |
Ros E et al. | A walnut diet improves endothelial function in hypercholesterolemic subjects: a randomized crossover trial. | 2004 | Circulation | pmid:15037535 |
Brouwer IA et al. | Dietary alpha-linolenic acid is associated with reduced risk of fatal coronary heart disease, but increased prostate cancer risk: a meta-analysis. | 2004 | J. Nutr. | pmid:15051847 |
Maffei M et al. | Effects of feeding Spodoptera littoralis on lima bean leaves. I. Membrane potentials, intracellular calcium variations, oral secretions, and regurgitate components. | 2004 | Plant Physiol. | pmid:15051862 |
Burdge G | Alpha-linolenic acid metabolism in men and women: nutritional and biological implications. | 2004 | Curr Opin Clin Nutr Metab Care | pmid:15075703 |
Padilla S et al. | Demethoxy-Q, an intermediate of coenzyme Q biosynthesis, fails to support respiration in Saccharomyces cerevisiae and lacks antioxidant activity. | 2004 | J. Biol. Chem. | pmid:15078893 |
Nielsen GS et al. | Formation of volatile compounds in model experiments with crude leek (Allium ampeloprasum Var. Lancelot) enzyme extract and linoleic acid or linolenic acid. | 2004 | J. Agric. Food Chem. | pmid:15080639 |
Speake BK et al. | Comparison of the fatty-acid compositions of prey items and yolks of Australian insectivorous scincid lizards. | 2004 | J. Comp. Physiol. B, Biochem. Syst. Environ. Physiol. | pmid:15085383 |
Kodas E et al. | Serotoninergic neurotransmission is affected by n-3 polyunsaturated fatty acids in the rat. | 2004 | J. Neurochem. | pmid:15086526 |
Cardoso CR et al. | Influence of topical administration of n-3 and n-6 essential and n-9 nonessential fatty acids on the healing of cutaneous wounds. | 2004 Mar-Apr | Wound Repair Regen | pmid:15086775 |
Ipatova OM et al. | [Biological activity of linseed oil as the source of omega-3 alpha-linolenic acid]. | 2004 Jan-Feb | Biomed Khim | pmid:15108624 |
Frey M et al. | Transcriptional activation of Igl, the gene for indole formation in Zea mays: a structure-activity study with elicitor-active N-acyl glutamines from insects. | 2004 | Phytochemistry | pmid:15110684 |
Torstensen BE and Stubhaug I | Beta-oxidation of 18:3n-3 in Atlantic salmon (Salmo salar L.) hepatocytes treated with different fatty acids. | 2004 | Lipids | pmid:15134142 |
Delmonte P et al. | Synthesis, isolation, and GC analysis of all the 6,8- to 13,15-cis/trans conjugated linoleic acid isomers. | 2004 | Lipids | pmid:15134147 |
Rallidis LS et al. | The effect of diet enriched with alpha-linolenic acid on soluble cellular adhesion molecules in dyslipidaemic patients. | 2004 | Atherosclerosis | pmid:15135261 |
Menendez JA et al. | Overexpression and hyperactivity of breast cancer-associated fatty acid synthase (oncogenic antigen-519) is insensitive to normal arachidonic fatty acid-induced suppression in lipogenic tissues but it is selectively inhibited by tumoricidal alpha-linolenic and gamma-linolenic fatty acids: a novel mechanism by which dietary fat can alter mammary tumorigenesis. | 2004 | Int. J. Oncol. | pmid:15138577 |
Astorg P | Dietary N-6 and N-3 polyunsaturated fatty acids and prostate cancer risk: a review of epidemiological and experimental evidence. | 2004 | Cancer Causes Control | pmid:15141138 |
Bertrandt J et al. | Influence of vitamin B6 supplementation on polyunsaturated fatty acids concentration in serum and liver of rats fed a diet restricted in protein. | 2004 | Nahrung | pmid:15146965 |
Nelson TL and Hickey MS | Acute changes in dietary omega-3 fatty acid intake lowers soluble interleukin-6 receptor in healthy adult normal weight and overweight males. | 2004 | Cytokine | pmid:15157896 |
Jia Q et al. | Docosahexaenoic acid and eicosapentaenoic acid, but not alpha-linolenic acid, suppress deoxynivalenol-induced experimental IgA nephropathy in mice. | 2004 | J. Nutr. | pmid:15173396 |
Fraser TC et al. | Expression of the Isochrysis C18-delta9 polyunsaturated fatty acid specific elongase component alters Arabidopsis glycerolipid profiles. | 2004 | Plant Physiol. | pmid:15173563 |
Moriguchi T et al. | Effects of an n-3-deficient diet on brain, retina, and liver fatty acyl composition in artificially reared rats. | 2004 | J. Lipid Res. | pmid:15175358 |
De Moraes CM and Mescher MC | Biochemical crypsis in the avoidance of natural enemies by an insect herbivore. | 2004 | Proc. Natl. Acad. Sci. U.S.A. | pmid:15184664 |
Wijendran V and Hayes KC | Dietary n-6 and n-3 fatty acid balance and cardiovascular health. | 2004 | Annu. Rev. Nutr. | pmid:15189133 |
Nguyen LQ et al. | Influence of dietary linseed, fish and coconut oil on growth performance of growing pigs kept on small holdings in central Vietnam. | 2004 | J Anim Physiol Anim Nutr (Berl) | pmid:15189425 |
Zhang HY et al. | Isolation and functional assessment of a tomato proteinase inhibitor II gene. | 2004 | Plant Physiol. Biochem. | pmid:15191748 |
Onyango AN et al. | The rapid oxidative degradation of a phosphatidylcholine bearing an oxidatively modified acyl chain with a 2,4-dienal terminal. | 2004 | Chem. Phys. Lipids | pmid:15210367 |