MeSH term | MeSH ID | Detail |
---|---|---|
Irritable Bowel Syndrome | D043183 | 8 associated lipids |
Overweight | D050177 | 11 associated lipids |
Atherosclerosis | D050197 | 85 associated lipids |
Carcinogenesis | D063646 | 3 associated lipids |
Alpha-linolenic acid is a lipid of Fatty Acyls (FA) class. Alpha-linolenic acid is associated with abnormalities such as Coronary heart disease, abnormal fragmented structure, Arterial thrombosis and Subarachnoid Hemorrhage. The involved functions are known as Anabolism, Signal, Transcription, Genetic, Saturated and Regulation. Alpha-linolenic acid often locates in Blood, Body tissue, Plasma membrane, Hepatic and peroxisome. The associated genes with alpha-linolenic acid are FATE1 gene, volicitin, CYP2U1 gene, CYP1A2 gene and CYP2J2 gene. The related lipids are Fatty Acids, Dietary Fatty Acid, stearidonic acid and Fatty Acids, Nonesterified.
To understand associated biological information of alpha-linolenic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
alpha-linolenic acid is suspected in Coronary heart disease, Arterial thrombosis, Subarachnoid Hemorrhage and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with alpha-linolenic acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Berghaus TM et al. | Essential fatty acids and their long-chain polyunsaturated metabolites in maternal and cord plasma triglycerides during late gestation. | 2000 | Biol. Neonate | pmid:10657686 |
Motaung E et al. | Cytotoxicity of combined essential fatty acids on a human prostate cancer cell line. | 1999 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:10670696 |
Larqué E et al. | Dietary trans fatty acids affect docosahexaenoic acid concentrations in plasma and liver but not brain of pregnant and fetal rats. | 2000 | Pediatr. Res. | pmid:10674359 |
McGahon BM et al. | Age-related changes in oxidative mechanisms and LTP are reversed by dietary manipulation. | 1999 Nov-Dec | Neurobiol. Aging | pmid:10674430 |
Sébédio JL et al. | The effect of dietary trans alpha-linolenic acid on plasma lipids and platelet fatty acid composition: the TransLinE study. | 2000 | Eur J Clin Nutr | pmid:10694780 |
Klein V et al. | Low alpha-linolenic acid content of adipose breast tissue is associated with an increased risk of breast cancer. | 2000 | Eur. J. Cancer | pmid:10708934 |
Fu Z and Sinclair AJ | Novel pathway of metabolism of alpha-linolenic acid in the guinea pig. | 2000 | Pediatr. Res. | pmid:10709744 |
Umezawa M et al. | Serum lipid concentrations and mean life span are modulated by dietary polyunsaturated fatty acids in the senescence-accelerated mouse. | 2000 | J. Nutr. | pmid:10720173 |
Tsuge H et al. | Effects of vitamin B-6 on (n-3) polyunsaturated fatty acid metabolism. | 2000 | J. Nutr. | pmid:10721899 |
Kemp B et al. | Influence of linoleic/linolenic acid ratio in the diet of periparturient cattle on plasma concentrations of PGF2 alpha metabolite and placental expulsion rate. | 1998 | Theriogenology | pmid:10732036 |
Okamoto M et al. | Effects of dietary supplementation with n-3 fatty acids compared with n-6 fatty acids on bronchial asthma. | 2000 | Intern. Med. | pmid:10732825 |
Ezaki O et al. | Long-term effects of dietary alpha-linolenic acid from perilla oil on serum fatty acids composition and on the risk factors of coronary heart disease in Japanese elderly subjects. | 1999 | J. Nutr. Sci. Vitaminol. | pmid:10737229 |
De Stéfani E et al. | Alpha-linolenic acid and risk of prostate cancer: a case-control study in Uruguay. | 2000 | Cancer Epidemiol. Biomarkers Prev. | pmid:10750674 |
Yokoyama M et al. | Stress-induced factor involved in flower formation of Lemna is an alpha-ketol derivative of linolenic acid. | 2000 | Plant Cell Physiol. | pmid:10750715 |
Imbusch R and Mueller MJ | Formation of isoprostane F(2)-like compounds (phytoprostanes F(1)) from alpha-linolenic acid in plants. | 2000 | Free Radic. Biol. Med. | pmid:10754267 |
Vermunt SH et al. | Effects of dietary alpha-linolenic acid on the conversion and oxidation of 13C-alpha-linolenic acid. | 2000 | Lipids | pmid:10757543 |
Punchard NA et al. | Analysis of the intestinal absorption of essential fatty acids in vivo in the rat. | 2000 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:10765976 |
Lauritzen I et al. | Polyunsaturated fatty acids are potent neuroprotectors. | 2000 | EMBO J. | pmid:10775263 |
Allen PC et al. | Effects of nutritionally balanced and stabilized flaxmeal-based diets on Eimeria tenella infections in chickens. | 2000 | Poult. Sci. | pmid:10780643 |
Charnock JS | Gamma-linolenic acid provides additional protection against ventricular fibrillation in aged rats fed linoleic acid rich diets. | 2000 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:10780878 |