MeSH term | MeSH ID | Detail |
---|---|---|
Irritable Bowel Syndrome | D043183 | 8 associated lipids |
Overweight | D050177 | 11 associated lipids |
Atherosclerosis | D050197 | 85 associated lipids |
Carcinogenesis | D063646 | 3 associated lipids |
Alpha-linolenic acid is a lipid of Fatty Acyls (FA) class. Alpha-linolenic acid is associated with abnormalities such as Coronary heart disease, abnormal fragmented structure, Arterial thrombosis and Subarachnoid Hemorrhage. The involved functions are known as Anabolism, Signal, Transcription, Genetic, Saturated and Regulation. Alpha-linolenic acid often locates in Blood, Body tissue, Plasma membrane, Hepatic and peroxisome. The associated genes with alpha-linolenic acid are FATE1 gene, volicitin, CYP2U1 gene, CYP1A2 gene and CYP2J2 gene. The related lipids are Fatty Acids, Dietary Fatty Acid, stearidonic acid and Fatty Acids, Nonesterified.
To understand associated biological information of alpha-linolenic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
alpha-linolenic acid is suspected in Coronary heart disease, Arterial thrombosis, Subarachnoid Hemorrhage and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with alpha-linolenic acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Childs CE et al. | Increased dietary α-linolenic acid has sex-specific effects upon eicosapentaenoic acid status in humans: re-examination of data from a randomised, placebo-controlled, parallel study. | 2014 | Nutr J | pmid:25496415 |
Thamphiwatana S et al. | In vivo treatment of Helicobacter pylori infection with liposomal linolenic acid reduces colonization and ameliorates inflammation. | 2014 | Proc. Natl. Acad. Sci. U.S.A. | pmid:25422427 |
Petrogianni M et al. | Additional benefit in CVD risk indices derived from the consumption of fortified milk when combined with a lifestyle intervention. | 2014 | Public Health Nutr | pmid:23249766 |
Ponnampalam EN et al. | Health beneficial long chain omega-3 fatty acid levels in Australian lamb managed under extensive finishing systems. | 2014 | Meat Sci. | pmid:23643471 |
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He F et al. | Perinatal α-linolenic acid availability alters the expression of genes related to memory and to epigenetic machinery, and the Mecp2 DNA methylation in the whole brain of mouse offspring. | 2014 | Int. J. Dev. Neurosci. | pmid:24866706 |
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Qin G et al. | Evolution of the aroma volatiles of pear fruits supplemented with fatty acid metabolic precursors. | 2014 | Molecules | pmid:25474290 |
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Purushothaman D et al. | Flaxseed oil supplementation alters the expression of inflammatory-related genes in dogs. | 2014 | Genet. Mol. Res. | pmid:25078588 |
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Lane K et al. | Bioavailability and potential uses of vegetarian sources of omega-3 fatty acids: a review of the literature. | 2014 | Crit Rev Food Sci Nutr | pmid:24261532 |
Carbonera F et al. | Effect of dietary replacement of sunflower oil with perilla oil on the absolute fatty acid composition in Nile tilapia (GIFT). | 2014 | Food Chem | pmid:24262550 |
Herchi W et al. | Flaxseed hull: Chemical composition and antioxidant activity during development. | 2014 | J Oleo Sci | pmid:24919478 |
Morris JB et al. | Flavonol content, oil%, and fatty acid composition variability in seeds of Teramnus labialis and T. uncinatus accessions with nutraceutical potential. | 2014 | J Diet Suppl | pmid:25054688 |
Mariutto M et al. | Reprogramming of fatty acid and oxylipin synthesis in rhizobacteria-induced systemic resistance in tomato. | 2014 | Plant Mol. Biol. | pmid:24146221 |
Matravadia S et al. | Both linoleic and α-linolenic acid prevent insulin resistance but have divergent impacts on skeletal muscle mitochondrial bioenergetics in obese Zucker rats. | 2014 | Am. J. Physiol. Endocrinol. Metab. | pmid:24844257 |
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Gorina SS et al. | Detection and molecular cloning of CYP74Q1 gene: identification of Ranunculus acris leaf divinyl ether synthase. | 2014 | Biochim. Biophys. Acta | pmid:24863619 |
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Dai XW et al. | Erythrocyte membrane n-3 fatty acid levels and carotid atherosclerosis in Chinese men and women. | 2014 | Atherosclerosis | pmid:24401220 |
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Yuan X et al. | Accumulation of eicosapolyenoic acids enhances sensitivity to abscisic acid and mitigates the effects of drought in transgenic Arabidopsis thaliana. | 2014 | J. Exp. Bot. | pmid:24609499 |
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Soto-Cerda BJ et al. | Association mapping of seed quality traits using the Canadian flax (Linum usitatissimum L.) core collection. | 2014 | Theor. Appl. Genet. | pmid:24463785 |
Yavin E et al. | Metabolic conversion of intra-amniotically-injected deuterium-labeled essential fatty acids by fetal rats following maternal n-3 fatty acid deficiency. | 2014 | Biochim. Biophys. Acta | pmid:24960100 |
Wennman A et al. | Kinetic investigation of the rate-limiting step of manganese- and iron-lipoxygenases. | 2014 | Arch. Biochem. Biophys. | pmid:24857825 |
Liang CH et al. | Synthesis of doxorubicin α-linolenic acid conjugate and evaluation of its antitumor activity. | 2014 | Mol. Pharm. | pmid:24720787 |
Yang Q et al. | Anti-thrombotic effects of α-linolenic acid isolated from Zanthoxylum bungeanum Maxim seeds. | 2014 | BMC Complement Altern Med | pmid:25252789 |
Khodadoust S et al. | Identification and determination of the fatty acid composition of Quercus brantii growing in southwestern Iran by GC-MS. | 2014 | Nat. Prod. Res. | pmid:24499169 |