MeSH term | MeSH ID | Detail |
---|---|---|
Irritable Bowel Syndrome | D043183 | 8 associated lipids |
Overweight | D050177 | 11 associated lipids |
Atherosclerosis | D050197 | 85 associated lipids |
Carcinogenesis | D063646 | 3 associated lipids |
Alpha-linolenic acid is a lipid of Fatty Acyls (FA) class. Alpha-linolenic acid is associated with abnormalities such as Coronary heart disease, abnormal fragmented structure, Arterial thrombosis and Subarachnoid Hemorrhage. The involved functions are known as Anabolism, Signal, Transcription, Genetic, Saturated and Regulation. Alpha-linolenic acid often locates in Blood, Body tissue, Plasma membrane, Hepatic and peroxisome. The associated genes with alpha-linolenic acid are FATE1 gene, volicitin, CYP2U1 gene, CYP1A2 gene and CYP2J2 gene. The related lipids are Fatty Acids, Dietary Fatty Acid, stearidonic acid and Fatty Acids, Nonesterified.
To understand associated biological information of alpha-linolenic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
alpha-linolenic acid is suspected in Coronary heart disease, Arterial thrombosis, Subarachnoid Hemorrhage and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
---|
We collected disease MeSH terms mapped to the references associated with alpha-linolenic acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
---|
Function | Cross reference | Weighted score | Related literatures |
---|
Lipid concept | Cross reference | Weighted score | Related literatures |
---|
Gene | Cross reference | Weighted score | Related literatures |
---|
There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
---|---|---|---|---|
Crutchley DJ | Hydroxyeicosatetraenoic acids and other unsaturated fatty acids inhibit endotoxin-induced thromboplastin activity in human monocytes. | 1985 | Biochem. Biophys. Res. Commun. | pmid:2865954 |
pmid:28651694 | ||||
pmid:28651693 | ||||
Budowski P and Crawford MA | a-Linolenic acid as a regulator of the metabolism of arachidonic acid: dietary implications of the ratio, n-6:n-3 fatty acids. | 1985 | Proc Nutr Soc | pmid:2864692 |
pmid:28646265 | ||||
Morisaki N et al. | Metabolism of n-3 polyunsaturated fatty acids and modification of phospholipids in cultured rabbit aortic smooth muscle cells. | 1985 | J. Lipid Res. | pmid:2864379 |
pmid:28643621 | ||||
Oki E et al. | Polymorphisms of the TNF-α gene interact with plasma fatty acids on inflammatory biomarker profile: a population-based, cross-sectional study in São Paulo, Brazil. | 2017 | Br. J. Nutr. | pmid:28633686 |
pmid:28628798 | ||||
Angkasa D et al. | Inadequate dietary α-linolenic acid intake among Indonesian pregnant women is associated with lower newborn weights in urban Jakarta. | 2017 | Asia Pac J Clin Nutr | pmid:28625031 |
Nordøy A et al. | Effect of dietary (n--3) fatty acids on platelet function and lipid metabolism in rats. | 1985 | Biochim. Biophys. Acta | pmid:2861854 |
Gutteridge JM et al. | Aluminium salts accelerate peroxidation of membrane lipids stimulated by iron salts. | 1985 | Biochim. Biophys. Acta | pmid:2861853 |
Das UN | Antibiotic-like action of essential fatty acids. | 1985 | Can Med Assoc J | pmid:2860965 |
pmid:28605735 | ||||
Piconneaux A et al. | [Identification of an atypical polyunsaturated fatty acid present in the liver of rats after the ingestion of heated linseed oil]. | 1985 | C. R. Acad. Sci. III, Sci. Vie | pmid:2859918 |
Becker W et al. | Uptake of radiolabelled alpha-linolenic, arachidonic and oleic acid in tissues of normal and essential fatty acid-deficient rats--an autoradiographic study. | 1985 | Ann. Nutr. Metab. | pmid:2859826 |
Nakamura T | Red pigment-forming substances from autoxidized linolenate: identification of prostaglandin-like substances. | 1985 | Lipids | pmid:2859511 |
McClead RE et al. | Comparison of the clinical and biochemical effect of increased alpha-linolenic acid in a safflower oil intravenous fat emulsion. | 1985 | J. Pediatr. Gastroenterol. Nutr. | pmid:2859362 |
pmid:28582540 | ||||
Azizova OA et al. | [Initiation of nonenzymatic lipid peroxidation in a Fe2+-ascorbate-linolenate system]. | 1985 Jan-Feb | Biofizika | pmid:2858224 |
Wang XH et al. | High Fat Diet-Induced Hepatic 18-Carbon Fatty Acids Accumulation Up-Regulates CYP2A5/CYP2A6 via NF-E2-Related Factor 2. | 2017 | Front Pharmacol | pmid:28555106 |
Jovanovski E et al. | The effect of alpha-linolenic acid on glycemic control in individuals with type 2 diabetes: A systematic review and meta-analysis of randomized controlled clinical trials. | 2017 | Medicine (Baltimore) | pmid:28538363 |
pmid:28520897 | ||||
Leroy C et al. | Fatty acid-binding protein3 expression in BeWo cells, a human placental choriocarcinoma cell line. | 2017 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:28515017 |
pmid:28504119 | ||||
pmid:28481011 | ||||
pmid:28468892 | ||||
pmid:28465188 | ||||
Kim H et al. | Association between maternal intake of n-6 to n-3 fatty acid ratio during pregnancy and infant neurodevelopment at 6 months of age: results of the MOCEH cohort study. | 2017 | Nutr J | pmid:28420388 |
pmid:28418808 | ||||
pmid:28410669 | ||||
pmid:28410665 | ||||
pmid:28406725 | ||||
Bentrad N et al. | Identification and evaluation of antibacterial agents present in lipophilic fractions isolated from sub-products of Phoenix dactilyfera. | 2017 | Nat. Prod. Res. | pmid:28403631 |
Zheng JS et al. | Genetic Risk Score of Nine Type 2 Diabetes Risk Variants that Interact with Erythrocyte Phospholipid Alpha-Linolenic Acid for Type 2 Diabetes in Chinese Hans: A Case-Control Study. | 2017 | Nutrients | pmid:28398239 |
Lodolini EM et al. | Oil Characteristics of Four Palestinian Olive Varieties. | 2017 | J Oleo Sci | pmid:28381771 |
pmid:28380598 | ||||
pmid:28374423 | ||||
Guo Q et al. | Highly sensitive method for the quantification of trans-linolenic acid isomers in trilinolenin of edible oils using an ionic liquid capillary column. | 2017 | J. Sci. Food Agric. | pmid:28369919 |
pmid:28367773 | ||||
Burak C et al. | Effects of the flavonol quercetin and α-linolenic acid on n-3 PUFA status in metabolically healthy men and women: a randomised, double-blinded, placebo-controlled, crossover trial. | 2017 | Br. J. Nutr. | pmid:28366181 |
pmid:28357649 | ||||
Veselinovic M et al. | Clinical Benefits of n-3 PUFA and ɤ-Linolenic Acid in Patients with Rheumatoid Arthritis. | 2017 | Nutrients | pmid:28346333 |
pmid:28345766 | ||||
pmid:28324248 | ||||
pmid:28303390 | ||||
Lefort N et al. | Dietary Buglossoides Arvensis Oil Increases Circulating n-3 Polyunsaturated Fatty Acids in a Dose-Dependent Manner and Enhances Lipopolysaccharide-Stimulated Whole Blood Interleukin-10-A Randomized Placebo-Controlled Trial. | 2017 | Nutrients | pmid:28287415 |
pmid:28270444 | ||||
pmid:28263808 | ||||
pmid:28260396 |