| MeSH term | MeSH ID | Detail |
|---|---|---|
| Hyperlipidemias | D006949 | 73 associated lipids |
| Hypercholesterolemia | D006937 | 91 associated lipids |
| Carcinoma, Hepatocellular | D006528 | 140 associated lipids |
| Hemolysis | D006461 | 131 associated lipids |
| Heart Failure | D006333 | 36 associated lipids |
| Hearing Loss, High-Frequency | D006316 | 1 associated lipids |
| Fatty Liver | D005234 | 48 associated lipids |
| Mental Fatigue | D005222 | 3 associated lipids |
| Epilepsy | D004827 | 35 associated lipids |
| Endomyocardial Fibrosis | D004719 | 4 associated lipids |
alpha-linolenic acid
Alpha-linolenic acid is a lipid of Fatty Acyls (FA) class. Alpha-linolenic acid is associated with abnormalities such as Coronary heart disease, abnormal fragmented structure, Arterial thrombosis and Subarachnoid Hemorrhage. The involved functions are known as Anabolism, Signal, Transcription, Genetic, Saturated and Regulation. Alpha-linolenic acid often locates in Blood, Body tissue, Plasma membrane, Hepatic and peroxisome. The associated genes with alpha-linolenic acid are FATE1 gene, volicitin, CYP2U1 gene, CYP1A2 gene and CYP2J2 gene. The related lipids are Fatty Acids, Dietary Fatty Acid, stearidonic acid and Fatty Acids, Nonesterified.
Cross Reference
Introduction
To understand associated biological information of alpha-linolenic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with alpha-linolenic acid?
alpha-linolenic acid is suspected in Coronary heart disease, Arterial thrombosis, Subarachnoid Hemorrhage and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
Loading... please refresh the page if content is not showing up.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with alpha-linolenic acid
PubChem Associated disorders and diseases
What pathways are associated with alpha-linolenic acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with alpha-linolenic acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What functions are associated with alpha-linolenic acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with alpha-linolenic acid?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What genes are associated with alpha-linolenic acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with alpha-linolenic acid?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with alpha-linolenic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Pany S et al. | PKC activation by resveratrol derivatives with unsaturated aliphatic chain. | 2012 | PLoS ONE | pmid:23285216 |
| Wang Z et al. | De novo characterization of the banana root transcriptome and analysis of gene expression under Fusarium oxysporum f. sp. Cubense tropical race 4 infection. | 2012 | BMC Genomics | pmid:23170772 |
| Astiz M et al. | Exogenous arachidonate restores the dimethoate-induced inhibition of steroidogenesis in rat interstitial cells. | 2012 | Lipids | pmid:22476691 |
| Macášek J et al. | Plasma fatty acid composition in patients with pancreatic cancer: correlations to clinical parameters. | 2012 | Nutr Cancer | pmid:23061902 |
| Vanden Heuvel JP et al. | Mechanistic examination of walnuts in prevention of breast cancer. | 2012 | Nutr Cancer | pmid:23061909 |
| Vedtofte MS et al. | The role of essential fatty acids in the control of coronary heart disease. | 2012 | Curr Opin Clin Nutr Metab Care | pmid:23037902 |
| Kim DH et al. | Gamma linolenic acid exerts anti-inflammatory and anti-fibrotic effects in diabetic nephropathy. | 2012 | Yonsei Med. J. | pmid:23074118 |
| Pan A et al. | α-Linolenic acid and risk of cardiovascular disease: a systematic review and meta-analysis. | 2012 | Am. J. Clin. Nutr. | pmid:23076616 |
| Hennessy AA et al. | The production of conjugated α-linolenic, γ-linolenic and stearidonic acids by strains of bifidobacteria and propionibacteria. | 2012 | Lipids | pmid:22160449 |
| Valentine CJ | Maternal dietary DHA supplementation to improve inflammatory outcomes in the preterm infant. | 2012 | Adv Nutr | pmid:22585914 |
| González-Mañán D et al. | Bioconversion of α-linolenic acid to n-3 LCPUFA and expression of PPAR-alpha, acyl Coenzyme A oxidase 1 and carnitine acyl transferase I are incremented after feeding rats with α-linolenic acid-rich oils. | 2012 | Food Funct | pmid:22588205 |
| Vecchio AJ et al. | Investigating substrate promiscuity in cyclooxygenase-2: the role of Arg-120 and residues lining the hydrophobic groove. | 2012 | J. Biol. Chem. | pmid:22637474 |
| Jiang M et al. | [Protective effect of ALA on high glucose induced cellular injury of LLC-PK1 cell]. | 2012 | Wei Sheng Yan Jiu | pmid:22611923 |
| Ngaki MN et al. | Evolution of the chalcone-isomerase fold from fatty-acid binding to stereospecific catalysis. | 2012 | Nature | pmid:22622584 |
| Yang Q et al. | Identification of FAD2 and FAD3 genes in Brassica napus genome and development of allele-specific markers for high oleic and low linolenic acid contents. | 2012 | Theor. Appl. Genet. | pmid:22534790 |
| von Berlepsch S et al. | The acyl-acyl carrier protein synthetase from Synechocystis sp. PCC 6803 mediates fatty acid import. | 2012 | Plant Physiol. | pmid:22535424 |
| Tyagi A et al. | Attenuation of colonic inflammation by partial replacement of dietary linoleic acid with α-linolenic acid in a rat model of inflammatory bowel disease. | 2012 | Br. J. Nutr. | pmid:22243775 |
| Thomas T et al. | The effect of a 1-year multiple micronutrient or n-3 fatty acid fortified food intervention on morbidity in Indian school children. | 2012 | Eur J Clin Nutr | pmid:22009072 |
| Alessandri JM et al. | Influence of gender on DHA synthesis: the response of rat liver to low dietary α-linolenic acid evidences higher ω3 ∆4-desaturation index in females. | 2012 | Eur J Nutr | pmid:21647669 |
| Raatz SK et al. | Total dietary fat and fatty acid content modifies plasma phospholipid fatty acids, desaturase activity indices, and urinary prostaglandin E in women. | 2012 | Nutr Res | pmid:22260857 |
| Zhang J et al. | Alpha-linolenic acid increases cholesterol efflux in macrophage-derived foam cells by decreasing stearoyl CoA desaturase 1 expression: evidence for a farnesoid-X-receptor mechanism of action. | 2012 | J. Nutr. Biochem. | pmid:21658928 |
| Poudyal H et al. | Lipid redistribution by α-linolenic acid-rich chia seed inhibits stearoyl-CoA desaturase-1 and induces cardiac and hepatic protection in diet-induced obese rats. | 2012 | J. Nutr. Biochem. | pmid:21429727 |
| Regensburger J et al. | Fatty acids and vitamins generate singlet oxygen under UVB irradiation. | 2012 | Exp. Dermatol. | pmid:22229443 |
| Padilla MN et al. | Molecular cloning, functional characterization and transcriptional regulation of a 9-lipoxygenase gene from olive. | 2012 | Phytochemistry | pmid:22169502 |
| Levitan EB et al. | α-Linolenic acid, linoleic acid and heart failure in women. | 2012 | Br. J. Nutr. | pmid:22172525 |
| Yang G et al. | Duodenal infusion of α-linolenic acid affects fatty acid metabolism in the mammary gland of lactating dairy cows. | 2012 | J. Dairy Sci. | pmid:22921622 |
| Umesha SS and Naidu KA | Vegetable oil blends with α-linolenic acid rich Garden cress oil modulate lipid metabolism in experimental rats. | 2012 | Food Chem | pmid:22980881 |
| Gupta R and Prabhune AA | Structural determination and chemical esterification of the sophorolipids produced by Candida bombicola grown on glucose and α-linolenic acid. | 2012 | Biotechnol. Lett. | pmid:22167634 |
| Poudel-Tandukar K et al. | Relationship of serum fatty acid composition and desaturase activity to C-reactive protein in Japanese men and women. | 2012 | Atherosclerosis | pmid:22153152 |
| Zheng MM et al. | Immobilization of Candida rugosa lipase on hydrophobic/strong cation-exchange functional silica particles for biocatalytic synthesis of phytosterol esters. | 2012 | Bioresour. Technol. | pmid:22209442 |
| Ogawa N et al. | Intestinal fatty acid infusion modulates food preference as well as calorie intake via the vagal nerve and midbrain-hypothalamic neural pathways in rats. | 2012 | Metab. Clin. Exp. | pmid:22445513 |
| Chiu CC et al. | Associations between n-3 PUFA concentrations and cognitive function after recovery from late-life depression. | 2012 | Am. J. Clin. Nutr. | pmid:22218153 |
| Lemaitre RN et al. | Circulating and dietary α-linolenic acid and incidence of congestive heart failure in older adults: the Cardiovascular Health Study. | 2012 | Am. J. Clin. Nutr. | pmid:22743310 |
| Zhang L et al. | Quantitative genomics of 30 complex phenotypes in Wagyu x Angus Fâ‚ progeny. | 2012 | Int. J. Biol. Sci. | pmid:22745575 |
| Pal M and Ghosh M | Studies on comparative efficacy of α-linolenic acid and α-eleostearic acid on prevention of organic mercury-induced oxidative stress in kidney and liver of rat. | 2012 | Food Chem. Toxicol. | pmid:22269903 |
| Arsenault D et al. | Chronic dietary intake of α-linolenic acid does not replicate the effects of DHA on passive properties of entorhinal cortex neurons. | 2012 | Br. J. Nutr. | pmid:21851757 |
| Ling PR et al. | Purified fish oil eliminating linoleic and alpha linolenic acid meets essential fatty acid requirements in rats. | 2012 | Metab. Clin. Exp. | pmid:22512821 |
| Smink W et al. | Linoleic and α-linolenic acid as precursor and inhibitor for the synthesis of long-chain polyunsaturated fatty acids in liver and brain of growing pigs. | 2012 | Animal | pmid:22436184 |
| Baars T et al. | Experimental improvement of cow milk fatty acid composition in organic winter diets. | 2012 | J. Sci. Food Agric. | pmid:22173628 |
| Turchini GM et al. | Jumping on the omega-3 bandwagon: distinguishing the role of long-chain and short-chain omega-3 fatty acids. | 2012 | Crit Rev Food Sci Nutr | pmid:22698270 |
| Botsoglou E et al. | Lipid and protein oxidation of α-linolenic acid-enriched pork during refrigerated storage as influenced by diet supplementation with olive leaves (Olea europea L.) or α-tocopheryl acetate. | 2012 | Meat Sci. | pmid:22710099 |
| Erdinest N et al. | Anti-inflammatory effects of alpha linolenic acid on human corneal epithelial cells. | 2012 | Invest. Ophthalmol. Vis. Sci. | pmid:22669722 |
| Chen CY and Inui A | What kind of polyunsaturated fatty acid should we eat to stay healthy? | 2012 | Nutrition | pmid:22658641 |
| Gómez-Cortés P et al. | Production of isotopically labeled standards from a uniformly labeled precursor for quantitative volatile metabolomic studies. | 2012 | Anal. Chem. | pmid:22662968 |
| Jin F et al. | Supplementation of milled chia seeds increases plasma ALA and EPA in postmenopausal women. | 2012 | Plant Foods Hum Nutr | pmid:22538527 |
| Gerber M | Omega-3 fatty acids and cancers: a systematic update review of epidemiological studies. | 2012 | Br. J. Nutr. | pmid:22591896 |
| Tu WC et al. | An alternative n-3 fatty acid elongation pathway utilising 18:3n-3 in barramundi (Lates calcarifer). | 2012 | Biochem. Biophys. Res. Commun. | pmid:22640739 |
| Vyncke KE et al. | Dietary fatty acid intake, its food sources and determinants in European adolescents: the HELENA (Healthy Lifestyle in Europe by Nutrition in Adolescence) Study. | 2012 | Br. J. Nutr. | pmid:22370331 |
| Park HG et al. | Production of a conjugated fatty acid by Bifidobacterium breve LMC520 from α-linolenic acid: conjugated linolenic acid (CLnA). | 2012 | J. Agric. Food Chem. | pmid:22372442 |
| Liu HL et al. | Identification and evaluation of ω-3 fatty acid desaturase genes for hyperfortifying α-linolenic acid in transgenic rice seed. | 2012 | J. Exp. Bot. | pmid:22378946 |