| MeSH term | MeSH ID | Detail |
|---|---|---|
| Dermatitis, Atopic | D003876 | 19 associated lipids |
| Vitamin E Deficiency | D014811 | 29 associated lipids |
| Adenoma | D000236 | 40 associated lipids |
| Learning Disorders | D007859 | 11 associated lipids |
| Retinitis Pigmentosa | D012174 | 6 associated lipids |
| Exocrine Pancreatic Insufficiency | D010188 | 6 associated lipids |
| Paraplegia | D010264 | 8 associated lipids |
| Zellweger Syndrome | D015211 | 39 associated lipids |
| Atrial Fibrillation | D001281 | 16 associated lipids |
| Vitamin B 6 Deficiency | D026681 | 10 associated lipids |
alpha-linolenic acid
Alpha-linolenic acid is a lipid of Fatty Acyls (FA) class. Alpha-linolenic acid is associated with abnormalities such as Coronary heart disease, abnormal fragmented structure, Arterial thrombosis and Subarachnoid Hemorrhage. The involved functions are known as Anabolism, Signal, Transcription, Genetic, Saturated and Regulation. Alpha-linolenic acid often locates in Blood, Body tissue, Plasma membrane, Hepatic and peroxisome. The associated genes with alpha-linolenic acid are FATE1 gene, volicitin, CYP2U1 gene, CYP1A2 gene and CYP2J2 gene. The related lipids are Fatty Acids, Dietary Fatty Acid, stearidonic acid and Fatty Acids, Nonesterified.
Cross Reference
Introduction
To understand associated biological information of alpha-linolenic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with alpha-linolenic acid?
alpha-linolenic acid is suspected in Coronary heart disease, Arterial thrombosis, Subarachnoid Hemorrhage and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
Loading... please refresh the page if content is not showing up.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with alpha-linolenic acid
PubChem Associated disorders and diseases
What pathways are associated with alpha-linolenic acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with alpha-linolenic acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What functions are associated with alpha-linolenic acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with alpha-linolenic acid?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What genes are associated with alpha-linolenic acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with alpha-linolenic acid?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with alpha-linolenic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Warden JT and Csatorday K | On the mechanism of linolenic acid inhibition in Photosystem II. | 1987 | Biochim. Biophys. Acta | pmid:2879567 |
| Gutteridge JM | The antioxidant activity of haptoglobin towards haemoglobin-stimulated lipid peroxidation. | 1987 | Biochim. Biophys. Acta | pmid:2879568 |
| Bjerve KS | Alpha-linolenic acid deficiency in adult women. | 1987 | Nutr. Rev. | pmid:2881237 |
| McDonald GB and Weidman M | Partitioning of polar fatty acids into lymph and portal vein after intestinal absorption in the rat. | 1987 | Q J Exp Physiol | pmid:2884690 |
| Bursztyn P | Does dietary linolenic acid influence blood pressure? | 1987 | Am. J. Clin. Nutr. | pmid:2884863 |
| Singer P et al. | Changes of N-6 and N-3 fatty acids in liver from spontaneously hypertensive (SHR) and normotensive rats after diets supplemented with alpha-linolenic or eicosapentaenoic acids. | 1987 | Prostaglandins Leukot Med | pmid:2888133 |
| Bjerve KS et al. | Alpha-linolenic acid deficiency in man: effect of essential fatty acids on fatty acid composition. | 1987 | Adv. Prostaglandin Thromboxane Leukot. Res. | pmid:2890285 |
| Astorg PO and Chevalier J | Polyunsaturated fatty acids in tissues of rats fed trielaidin and high or low levels of linolenic acid. | 1987 | Lipids | pmid:2897610 |
| Yamamoto N et al. | Effect of dietary alpha-linolenate/linoleate balance on brain lipid compositions and learning ability of rats. | 1987 | J. Lipid Res. | pmid:2883248 |
| Novo C et al. | Altered fatty acid membrane composition modifies lymphocyte localization in vivo. | 1987 | Cell. Immunol. | pmid:2882861 |
| Jones DB et al. | Glucose, insulin and platelet fatty acids following myocardial infarction: an association with infarct size. | 1987 Jul-Aug | Diabete Metab | pmid:3315767 |
| Choi YS and Sugano M | Effects of dietary alpha- and gamma-linolenic acid on lipid metabolism in young and adult rats. | 1988 | Ann. Nutr. Metab. | pmid:2903713 |
| Hashimoto A et al. | Effect of the dietary alpha-linolenate/linoleate balance on leukotriene production and histamine release in rats. | 1988 | Prostaglandins | pmid:2459732 |
| Urano S et al. | Membrane-stabilizing effect of vitamin E: effect of alpha-tocopherol and its model compounds on fluidity of lecithin liposomes. | 1988 | Biochem. Biophys. Res. Commun. | pmid:2892491 |
| Hwang DH et al. | Dietary linolenic acid and longer-chain n-3 fatty acids: comparison of effects on arachidonic acid metabolism in rats. | 1988 | J. Nutr. | pmid:2895804 |
| Arthur JR | Effects of selenium and vitamin E status on plasma creatine kinase activity in calves. | 1988 | J. Nutr. | pmid:2897437 |
| Guesnet P et al. | Effects of dietary alpha-linolenic acid deficiency during pregnancy and lactation on lipid fatty acid composition of liver and serum in the rat. | 1988 | Reprod Nutr Dev | pmid:2897705 |
| Koletzko B and Cunnane S | Human alpha-linolenic acid deficiency. | 1988 | Am. J. Clin. Nutr. | pmid:2897782 |
| Homayoun P et al. | Alteration in fatty acid composition of adult rat brain capillaries and choroid plexus induced by a diet deficient in n-3 fatty acids: slow recovery after substitution with a nondeficient diet. | 1988 | J. Neurochem. | pmid:2898007 |
| Fan WX | [Alpha-linolenic acid and its metabolites EPA and DHA]. | 1988 | Sheng Li Ke Xue Jin Zhan | pmid:2901141 |
| Garg ML et al. | Dietary cholesterol and/or n-3 fatty acid modulate delta 9-desaturase activity in rat liver microsomes. | 1988 | Biochim. Biophys. Acta | pmid:2901857 |
| Khokher MA and Dandona P | The effect of polyunsaturated fatty acids on rat adipocyte lipogenesis: the role of protein kinase C, calcium and calmodulin. | 1988 | Diabetes Res. | pmid:2906578 |
| Blasig IE et al. | Effect of troxerutin and methionine on spin trapping of free oxy-radicals. | 1988 | Biomed. Biochim. Acta | pmid:2907855 |
| Yamamoto N et al. | Effect of the dietary alpha-linolenate/linoleate balance on lipid compositions and learning ability of rats. II. Discrimination process, extinction process, and glycolipid compositions. | 1988 | J. Lipid Res. | pmid:2903207 |
| Whitcomb RW et al. | Effects of long-chain, saturated fatty acids on membrane microviscosity and adrenocorticotropin responsiveness of human adrenocortical cells in vitro. | 1988 | J. Clin. Invest. | pmid:2891726 |
| Chander A and Fisher AB | Choline-phosphate cytidyltransferase activity and phosphatidylcholine synthesis in rat granular pneumocytes are increased with exogenous fatty acids. | 1988 | Biochim. Biophys. Acta | pmid:2893643 |
| Sebokova E et al. | Modulation of receptor-mediated gonadotropin action in rat testes by dietary fat. | 1988 | Am. J. Physiol. | pmid:2897795 |
| Simopoulos AP | Summary of the NATO advanced research workshop on dietary omega 3 and omega 6 fatty acids: biological effects and nutritional essentiality. | 1989 | J. Nutr. | pmid:2564887 |
| Bjerve KS | n-3 fatty acid deficiency in man. | 1989 | J Intern Med Suppl | pmid:2565114 |
| Sprecher H | Interactions between the metabolism of n-3 and n-6 fatty acids. | 1989 | J Intern Med Suppl | pmid:2565115 |
| Schöneich C et al. | Thiyl radical attack on polyunsaturated fatty acids: a possible route to lipid peroxidation. | 1989 | Biochem. Biophys. Res. Commun. | pmid:2567162 |
| Fritsche KL and Johnston PV | Modulation of eicosanoid production and cell-mediated cytotoxicity by dietary alpha-linolenic acid in BALB/c mice. | 1989 | Lipids | pmid:2569149 |
| Garg ML et al. | Dietary saturated fat level alters the competition between alpha-linolenic and linoleic acid. | 1989 | Lipids | pmid:2569150 |
| Sok DE and Kim MR | The possible role of 9(S)-hydroperoxyoctadecatrienoic acid as a suicide substrate of soybean lipoxygenase. | 1989 | Biochem. Biophys. Res. Commun. | pmid:2569867 |
| Hashimoto Y et al. | Effect of black-pigmented Bacteroides gingivalis on cytotoxic activity of linolenic acid against mouse macrophages. | 1989 | Kitasato Arch. Exp. Med. | pmid:2570177 |
| Sharov VS et al. | Selective sensitization of chemiluminescence resulted from lipid and oxygen radical reactions. | 1989 | Free Radic. Biol. Med. | pmid:2570736 |
| Olaf A | Effects of linoleic and alpha linolenic acids intake on blood pressure in man. | 1989 | Prog. Clin. Biol. Res. | pmid:2571995 |
| Bourre JM et al. | The effects of dietary alpha-linolenic acid on the composition of nerve membranes, enzymatic activity, amplitude of electrophysiological parameters, resistance to poisons and performance of learning tasks in rats. | 1989 | J. Nutr. | pmid:2576038 |
| Bourre JM | [Nature, origin and role of fatty acids of the nervous system: an essential fatty acid, an alpha-linolenic acid, changing the structure and the cerebral function]. | 1989 | Bull. Acad. Natl. Med. | pmid:2576722 |
| Biliński T et al. | Superoxide dismutase deficiency and the toxicity of the products of autooxidation of polyunsaturated fatty acids in yeast. | 1989 | Biochim. Biophys. Acta | pmid:2563227 |
| Bourre JM et al. | Brain cell and tissue recovery in rats made deficient in n-3 fatty acids by alteration of dietary fat. | 1989 | J. Nutr. | pmid:2563284 |
| Bjerve KS et al. | alpha-Linolenic acid and long-chain omega-3 fatty acid supplementation in three patients with omega-3 fatty acid deficiency: effect on lymphocyte function, plasma and red cell lipids, and prostanoid formation. | 1989 | Am. J. Clin. Nutr. | pmid:2563625 |
| Hagve TA and Sprecher H | Metabolism of long-chain polyunsaturated fatty acids in isolated cardiac myocytes. | 1989 | Biochim. Biophys. Acta | pmid:2563660 |
| Romans JR | Alpha-linolenic acid. | 1989 | Lancet | pmid:2563803 |
| Hennig B and Watkins BA | Linoleic acid and linolenic acid: effect on permeability properties of cultured endothelial cell monolayers. | 1989 | Am. J. Clin. Nutr. | pmid:2563626 |
| D'Aquino M et al. | Vitamin A and glutathione-mediated free radical damage: competing reactions with polyunsaturated fatty acids and vitamin C. | 1989 | Biochem. Biophys. Res. Commun. | pmid:2568114 |
| Hrelia S et al. | Age-related changes in linoleate and alpha-linolenate desaturation by rat liver microsomes. | 1989 | Biochem. Biophys. Res. Commun. | pmid:2570573 |
| Buffière F et al. | Purification and characterization of monoclonal antibodies to alpha-linolenic acid. | 1989 Mar-Apr | J Lipid Mediat | pmid:2485142 |
| Hunter JE | n-3 fatty acids from vegetable oils. | 1990 | Am. J. Clin. Nutr. | pmid:1970702 |
| Bourre JM et al. | Nutritional fatty acids control. Composition and function of cerebral membranes. | 1990 | Bibl Nutr Dieta | pmid:1980414 |