alpha-linolenic acid

Alpha-linolenic acid is a lipid of Fatty Acyls (FA) class. Alpha-linolenic acid is associated with abnormalities such as Coronary heart disease, abnormal fragmented structure, Arterial thrombosis and Subarachnoid Hemorrhage. The involved functions are known as Anabolism, Signal, Transcription, Genetic, Saturated and Regulation. Alpha-linolenic acid often locates in Blood, Body tissue, Plasma membrane, Hepatic and peroxisome. The associated genes with alpha-linolenic acid are FATE1 gene, volicitin, CYP2U1 gene, CYP1A2 gene and CYP2J2 gene. The related lipids are Fatty Acids, Dietary Fatty Acid, stearidonic acid and Fatty Acids, Nonesterified.

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Introduction

To understand associated biological information of alpha-linolenic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with alpha-linolenic acid?

alpha-linolenic acid is suspected in Coronary heart disease, Arterial thrombosis, Subarachnoid Hemorrhage and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with alpha-linolenic acid

MeSH term MeSH ID Detail
Neuroblastoma D009447 66 associated lipids
Colitis D003092 69 associated lipids
Coronary Disease D003327 70 associated lipids
Hyperlipidemias D006949 73 associated lipids
Pancreatic Neoplasms D010190 77 associated lipids
Atherosclerosis D050197 85 associated lipids
Diabetes Mellitus, Experimental D003921 85 associated lipids
Arteriosclerosis D001161 86 associated lipids
Seizures D012640 87 associated lipids
Diabetes Mellitus, Type 2 D003924 87 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with alpha-linolenic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with alpha-linolenic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with alpha-linolenic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with alpha-linolenic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with alpha-linolenic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with alpha-linolenic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with alpha-linolenic acid

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Authors Title Published Journal PubMed Link
de Groot RH et al. Alpha-linolenic acid supplementation during human pregnancy does not effect cognitive functioning. 2004 Prostaglandins Leukot. Essent. Fatty Acids pmid:14643178
Sanders TA DHA status of vegetarians. 2009 Aug-Sep Prostaglandins Leukot. Essent. Fatty Acids pmid:19500961
Gueck T et al. Effects of essential fatty acids on mediators of mast cells in culture. 2003 Prostaglandins Leukot. Essent. Fatty Acids pmid:12711248
Joshi K et al. Supplementation with flax oil and vitamin C improves the outcome of Attention Deficit Hyperactivity Disorder (ADHD). 2006 Prostaglandins Leukot. Essent. Fatty Acids pmid:16314082
Tu WC et al. Correlations between blood and tissue omega-3 LCPUFA status following dietary ALA intervention in rats. 2013 Prostaglandins Leukot. Essent. Fatty Acids pmid:22521090
Arun Kumar C and Das UN Lipid peroxides, nitric oxide and essential fatty acids in patients with Plasmodium falciparum malaria. 1999 Prostaglandins Leukot. Essent. Fatty Acids pmid:10574650
Zhou D et al. Vitamin A deficiency reduces liver and colon docosahexaenoic acid levels in rats fed high linoleic and low alpha-linolenic acid diet. 2004 Prostaglandins Leukot. Essent. Fatty Acids pmid:15519497
Hrelia S et al. Role of gamma-linolenic acid in counteracting doxorubicin-induced damage in cultured rat cardiomyocytes. 2001 Prostaglandins Leukot. Essent. Fatty Acids pmid:11334548
Hofacer R et al. Omega-3 fatty acid deficiency increases stearoyl-CoA desaturase expression and activity indices in rat liver: positive association with non-fasting plasma triglyceride levels. 2012 Jan-Feb Prostaglandins Leukot. Essent. Fatty Acids pmid:22047910
Taha AY et al. Threshold changes in rat brain docosahexaenoic acid incorporation and concentration following graded reductions in dietary alpha-linolenic acid. 2016 Prostaglandins Leukot. Essent. Fatty Acids pmid:26869088