alpha-linolenic acid

Alpha-linolenic acid is a lipid of Fatty Acyls (FA) class. Alpha-linolenic acid is associated with abnormalities such as Coronary heart disease, abnormal fragmented structure, Arterial thrombosis and Subarachnoid Hemorrhage. The involved functions are known as Anabolism, Signal, Transcription, Genetic, Saturated and Regulation. Alpha-linolenic acid often locates in Blood, Body tissue, Plasma membrane, Hepatic and peroxisome. The associated genes with alpha-linolenic acid are FATE1 gene, volicitin, CYP2U1 gene, CYP1A2 gene and CYP2J2 gene. The related lipids are Fatty Acids, Dietary Fatty Acid, stearidonic acid and Fatty Acids, Nonesterified.

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Introduction

To understand associated biological information of alpha-linolenic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with alpha-linolenic acid?

alpha-linolenic acid is suspected in Coronary heart disease, Arterial thrombosis, Subarachnoid Hemorrhage and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with alpha-linolenic acid

MeSH term MeSH ID Detail
Hearing Loss, High-Frequency D006316 1 associated lipids
Aging, Premature D019588 1 associated lipids
Night Blindness D009755 1 associated lipids
Stomatitis, Aphthous D013281 1 associated lipids
Conjunctivitis, Allergic D003233 1 associated lipids
Torsades de Pointes D016171 2 associated lipids
Sebaceous Gland Neoplasms D012626 2 associated lipids
Otorhinolaryngologic Neoplasms D010039 2 associated lipids
Spinal Cord Ischemia D020760 2 associated lipids
Dyskinesias D020820 3 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with alpha-linolenic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with alpha-linolenic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with alpha-linolenic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with alpha-linolenic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with alpha-linolenic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with alpha-linolenic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with alpha-linolenic acid

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Authors Title Published Journal PubMed Link
Foster M et al. Inflammation markers predict zinc transporter gene expression in women with type 2 diabetes mellitus. 2013 J. Nutr. Biochem. pmid:23643522
Mapiye C et al. Effects of feeding flaxseed or sunflower-seed in high-forage diets on beef production, quality and fatty acid composition. 2013 Meat Sci. pmid:23669875
Monge-Rojas R et al. Changes in dietary intake and food sources of saturated and cis and trans unsaturated fatty acids in Costa Rican adolescents: 1996 versus 2006. 2013 Nutrition pmid:23298971
Stamey Lanier J et al. Mammary uptake of fatty acids supplied by intravenous triacylglycerol infusion to lactating dairy cows. 2013 Lipids pmid:23504269
Saubeau G et al. Differential induction of oxylipin pathway in potato and tobacco cells by bacterial and oomycete elicitors. 2013 Plant Cell Rep. pmid:23479199
Botelho PB et al. Effect of Echium oil compared with marine oils on lipid profile and inhibition of hepatic steatosis in LDLr knockout mice. 2013 Lipids Health Dis pmid:23510369
Cedernaes J et al. Adipose tissue stearoyl-CoA desaturase 1 index is increased and linoleic acid is decreased in obesity-prone rats fed a high-fat diet. 2013 Lipids Health Dis pmid:23298201
Kastner DW and Van Wagoner DR Diet and atrial fibrillation: does α-linolenic acid, a plant derived essential fatty acid, have an impact? 2013 J Am Heart Assoc pmid:23525415
Fretts AM et al. Associations of plasma phospholipid and dietary alpha linolenic acid with incident atrial fibrillation in older adults: the Cardiovascular Health Study. 2013 J Am Heart Assoc pmid:23525429
Kälber T et al. Effect of feeding buckwheat and chicory silages on fatty acid profile and cheese-making properties of milk from dairy cows. 2013 J. Dairy Res. pmid:23253429
Monteiro J et al. Oils rich in α-linolenic acid independently protect against characteristics of fatty liver disease in the Δ6-desaturase null mouse. 2013 Can. J. Physiol. Pharmacol. pmid:23746194
Gillingham LG et al. Dietary oils and FADS1-FADS2 genetic variants modulate [13C]α-linolenic acid metabolism and plasma fatty acid composition. 2013 Am. J. Clin. Nutr. pmid:23221573
Lohner S et al. Gender differences in the long-chain polyunsaturated fatty acid status: systematic review of 51 publications. 2013 Ann. Nutr. Metab. pmid:23327902
MacIntosh BA et al. Low-n-6 and low-n-6 plus high-n-3 diets for use in clinical research. 2013 Br. J. Nutr. pmid:23328113
Carey AN et al. The ability of walnut extract and fatty acids to protect against the deleterious effects of oxidative stress and inflammation in hippocampal cells. 2013 Nutr Neurosci pmid:23321679
Randall KM et al. Effects of dietary supplementation of coriander oil, in canola oil diets, on the metabolism of [1-(14)C] 18:3n-3 and [1-(14)C] 18:2n-6 in rainbow trout hepatocytes. 2013 Comp. Biochem. Physiol. B, Biochem. Mol. Biol. pmid:23867781
Oliva ME et al. Dietary Salba (Salvia hispanica L) seed rich in α-linolenic acid improves adipose tissue dysfunction and the altered skeletal muscle glucose and lipid metabolism in dyslipidemic insulin-resistant rats. 2013 Prostaglandins Leukot. Essent. Fatty Acids pmid:24120122
Shen JH et al. Effect of α-linolenic acid on streptozotocin-induced diabetic retinopathy indices in vivo. 2013 Arch. Med. Res. pmid:24120388
Ogata F et al. Study on analysis of waste edible oil with deterioration and removal of acid value, carbonyl value, and free fatty acid by a food additive (calcium silicate). 2013 J Oleo Sci pmid:23391535
Rodriguez-Leyva D et al. Potent antihypertensive action of dietary flaxseed in hypertensive patients. 2013 Hypertension pmid:24126178
Hoffmann I and Oliw EH Discovery of a linoleate 9S-dioxygenase and an allene oxide synthase in a fusion protein of Fusarium oxysporum. 2013 J. Lipid Res. pmid:24082064
Alhazzaa R et al. Bioconversion of α-linolenic acid into n-3 long-chain polyunsaturated fatty acid in hepatocytes and ad hoc cell culture optimisation. 2013 PLoS ONE pmid:24040040
Botsoglou E et al. Olive leaves (Olea europea L.) and α-tocopheryl acetate as feed antioxidants for improving the oxidative stability of α-linolenic acid-enriched eggs. 2013 J Anim Physiol Anim Nutr (Berl) pmid:22716021
Kartikasari LR et al. Dietary alpha-linolenic acid enhances omega-3 long chain polyunsaturated fatty acid levels in chicken tissues. 2012 Oct-Nov Prostaglandins Leukot. Essent. Fatty Acids pmid:22925778
Tsuzuki W Inconsistencies in a highly polar capillary gas chromatography column and necessity of column performance checks for trans fatty acid measurement. 2012 Nov-Dec J AOAC Int pmid:23451392
Hofacer R et al. Omega-3 fatty acid deficiency increases stearoyl-CoA desaturase expression and activity indices in rat liver: positive association with non-fasting plasma triglyceride levels. 2012 Jan-Feb Prostaglandins Leukot. Essent. Fatty Acids pmid:22047910
Harland DR et al. Acute effects of prostaglandin E1 and E2 on vascular reactivity and blood flow in situ in the chick chorioallantoic membrane. 2012 Aug-Sep Prostaglandins Leukot. Essent. Fatty Acids pmid:22858445
Barrett E et al. Bifidobacterium breve with α-linolenic acid and linoleic acid alters fatty acid metabolism in the maternal separation model of irritable bowel syndrome. 2012 PLoS ONE pmid:23185248
Fang XL et al. Roles of α-linolenic acid on IGF-I secretion and GH/IGF system gene expression in porcine primary hepatocytes. 2012 Mol. Biol. Rep. pmid:23053988
Gutla PV et al. Modulation of plant TPC channels by polyunsaturated fatty acids. 2012 J. Exp. Bot. pmid:23105130
Garcia CV et al. Characterisation of bound volatile compounds of a low flavour kiwifruit species: Actinidia eriantha. 2012 Food Chem pmid:23107675
Beck JJ et al. Generation of the volatile spiroketals conophthorin and chalcogran by fungal spores on polyunsaturated fatty acids common to almonds and pistachios. 2012 J. Agric. Food Chem. pmid:23153034
Sauerwald UC et al. Effect of different levels of docosahexaenoic acid supply on fatty acid status and linoleic and α-linolenic acid conversion in preterm infants. 2012 J. Pediatr. Gastroenterol. Nutr. pmid:22008957
Han SN et al. Novel soybean oils differing in fatty acid composition alter immune functions of moderately hypercholesterolemic older adults. 2012 J. Nutr. pmid:23096013
Jackson MD et al. Associations of whole-blood fatty acids and dietary intakes with prostate cancer in Jamaica. 2012 Cancer Causes Control pmid:21984307
He ML et al. Feeding flaxseed in grass hay and barley silage diets to beef cows increases alpha-linolenic acid and its biohydrogenation intermediates in subcutaneous fat. 2012 J. Anim. Sci. pmid:22274861
Nieman DC et al. Chia seed supplementation and disease risk factors in overweight women: a metabolomics investigation. 2012 J Altern Complement Med pmid:22830971
Janssen S et al. Sensing of fatty acids for octanoylation of ghrelin involves a gustatory G-protein. 2012 PLoS ONE pmid:22768248
Shen J et al. Effect of essential fatty acids on glucose-induced cytotoxicity to retinal vascular endothelial cells. 2012 Lipids Health Dis pmid:22781401
Garneau V et al. Omega-3 fatty acids status in human subjects estimated using a food frequency questionnaire and plasma phospholipids levels. 2012 Nutr J pmid:22775977
Pham AT et al. Combinations of mutant FAD2 and FAD3 genes to produce high oleic acid and low linolenic acid soybean oil. 2012 Theor. Appl. Genet. pmid:22476873
Rosa DD et al. Fish oil improves the lipid profile and reduces inflammatory cytokines in Wistar rats with precancerous colon lesions. 2012 Nutr Cancer pmid:22483364
Karppi J et al. Serum β-carotene in relation to risk of prostate cancer: the Kuopio Ischaemic Heart Disease Risk Factor study. 2012 Nutr Cancer pmid:22420939
Zhang G et al. Erythrocyte n-3 fatty acids and metabolic syndrome in middle-aged and older Chinese. 2012 J. Clin. Endocrinol. Metab. pmid:22456621
de Freitas JM et al. Influence of cellular fatty acid composition on the response of Saccharomyces cerevisiae to hydrostatic pressure stress. 2012 FEMS Yeast Res. pmid:22846157
Griffin BA Goldilocks and the three bonds: new evidence for the conditional benefits of dietary α-linolenic acid in treating cardiovascular risk in the metabolic syndrome. 2012 Br. J. Nutr. pmid:22894910
Baxheinrich A et al. Effects of a rapeseed oil-enriched hypoenergetic diet with a high content of α-linolenic acid on body weight and cardiovascular risk profile in patients with the metabolic syndrome. 2012 Br. J. Nutr. pmid:22894911
Nam KH and Yoshihara T Interactions among LOX metabolites regulate temperature-mediated flower bud formation in morning glory (Pharbitis nil). 2012 J. Plant Physiol. pmid:22902207
Evans SJ et al. Association of plasma ω-3 and ω-6 lipids with burden of disease measures in bipolar subjects. 2012 J Psychiatr Res pmid:22884424
Pan H et al. Alpha-linolenic acid is a potent neuroprotective agent against soman-induced neuropathology. 2012 Neurotoxicology pmid:22884490