alpha-linolenic acid

Alpha-linolenic acid is a lipid of Fatty Acyls (FA) class. Alpha-linolenic acid is associated with abnormalities such as Coronary heart disease, abnormal fragmented structure, Arterial thrombosis and Subarachnoid Hemorrhage. The involved functions are known as Anabolism, Signal, Transcription, Genetic, Saturated and Regulation. Alpha-linolenic acid often locates in Blood, Body tissue, Plasma membrane, Hepatic and peroxisome. The associated genes with alpha-linolenic acid are FATE1 gene, volicitin, CYP2U1 gene, CYP1A2 gene and CYP2J2 gene. The related lipids are Fatty Acids, Dietary Fatty Acid, stearidonic acid and Fatty Acids, Nonesterified.

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Introduction

To understand associated biological information of alpha-linolenic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with alpha-linolenic acid?

alpha-linolenic acid is suspected in Coronary heart disease, Arterial thrombosis, Subarachnoid Hemorrhage and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with alpha-linolenic acid

MeSH term MeSH ID Detail
Conjunctivitis, Allergic D003233 1 associated lipids
Aging, Premature D019588 1 associated lipids
Hearing Loss, High-Frequency D006316 1 associated lipids
Night Blindness D009755 1 associated lipids
Stomatitis, Aphthous D013281 1 associated lipids
Spinal Cord Ischemia D020760 2 associated lipids
Torsades de Pointes D016171 2 associated lipids
Sebaceous Gland Neoplasms D012626 2 associated lipids
Otorhinolaryngologic Neoplasms D010039 2 associated lipids
Mental Fatigue D005222 3 associated lipids
Carcinogenesis D063646 3 associated lipids
Depression, Postpartum D019052 3 associated lipids
Dyskinesias D020820 3 associated lipids
Endomyocardial Fibrosis D004719 4 associated lipids
Amyloidosis D000686 4 associated lipids
Insect Bites and Stings D007299 4 associated lipids
Retinitis Pigmentosa D012174 6 associated lipids
Exocrine Pancreatic Insufficiency D010188 6 associated lipids
Pancytopenia D010198 6 associated lipids
Urinary Bladder Neoplasms D001749 7 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with alpha-linolenic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with alpha-linolenic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with alpha-linolenic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with alpha-linolenic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with alpha-linolenic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with alpha-linolenic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with alpha-linolenic acid

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Authors Title Published Journal PubMed Link
Moore SA Local synthesis and targeting of essential fatty acids at the cellular interface between blood and brain: a role for cerebral endothelium and astrocytes in the accretion of CNS docosahexaenoic acid. 1994 World Rev Nutr Diet pmid:7871814
Bjerve KS Omega 3 fatty acid deficiency in man: implications for the requirement of alpha-linolenic acid and long-chain omega 3 fatty acids. 1991 World Rev Nutr Diet pmid:1675825
Okuyama H et al. alpha-linolenate-deficiency-induced alterations in brightness discrimination learning behavior and retinal function in rats. 2001 World Rev Nutr Diet pmid:11935967
Renaud SC and Lanzmann-Petithory D alpha-linolenic acid in the prevention of cardiovascular diseases. 2001 World Rev Nutr Diet pmid:11935975
Legrand P et al. Update of French nutritional recommendations for fatty acids. 2011 World Rev Nutr Diet pmid:21865827
Okuyama H et al. Omega3 fatty acids effectively prevent coronary heart disease and other late-onset diseases--the excessive linoleic acid syndrome. 2007 World Rev Nutr Diet pmid:17167282
Yang X et al. [Effects of silkworm pupa oil on serum lipids level and platelet function in rats]. 2002 Wei Sheng Yan Jiu pmid:12600031
Jiang M et al. [Protective effect of ALA on high glucose induced cellular injury of LLC-PK1 cell]. 2012 Wei Sheng Yan Jiu pmid:22611923
Zhang G et al. [Effects of fatty acids on proliferation and differentiation of myoblast]. 2012 Wei Sheng Yan Jiu pmid:23424861
Fein A and Cavar S Divergent mechanisms for phototransduction of invertebrate microvillar photoreceptors. 2000 Nov-Dec Vis. Neurosci. pmid:11193107