Alpha-linolenic acid is a lipid of Fatty Acyls (FA) class. Alpha-linolenic acid is associated with abnormalities such as Coronary heart disease, abnormal fragmented structure, Arterial thrombosis and Subarachnoid Hemorrhage. The involved functions are known as Anabolism, Signal, Transcription, Genetic, Saturated and Regulation. Alpha-linolenic acid often locates in Blood, Body tissue, Plasma membrane, Hepatic and peroxisome. The associated genes with alpha-linolenic acid are FATE1 gene, volicitin, CYP2U1 gene, CYP1A2 gene and CYP2J2 gene. The related lipids are Fatty Acids, Dietary Fatty Acid, stearidonic acid and Fatty Acids, Nonesterified.
To understand associated biological information of alpha-linolenic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
alpha-linolenic acid is suspected in Coronary heart disease, Arterial thrombosis, Subarachnoid Hemorrhage and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with alpha-linolenic acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Lipid concept | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
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pmid:26675329 | ||||
pmid:26674243 | ||||
Reddy YS et al. | Study on Synthesis, Characterization and Antiproliferative Activity of Novel Diisopropylphenyl Esters of Selected Fatty Acids. | 2016 | J Oleo Sci | pmid:26666272 |
Liu X et al. | APA-style human milk fat analogue from silkworm pupae oil: Enzymatic production and improving storage stability using alkyl caffeates. | 2015 | Sci Rep | pmid:26643045 |
Mata-Pérez C et al. | Nitro-Fatty Acids in Plant Signaling: Nitro-Linolenic Acid Induces the Molecular Chaperone Network in Arabidopsis. | 2016 | Plant Physiol. | pmid:26628746 |
pmid:26617007 | ||||
pmid:26615102 | ||||
Sun Y et al. | Plasma α-Linolenic and Long-Chain ω-3 Fatty Acids Are Associated with a Lower Risk of Acute Myocardial Infarction in Singapore Chinese Adults. | 2016 | J. Nutr. | pmid:26609174 |
Park HG et al. | Palmitic acid (16:0) competes with omega-6 linoleic and omega-3 ɑ-linolenic acids for FADS2 mediated Δ6-desaturation. | 2016 | Biochim. Biophys. Acta | pmid:26597785 |
pmid:26595854 | ||||
pmid:26593580 | ||||
pmid:26593514 | ||||
pmid:26584822 | ||||
pmid:26582578 | ||||
Piermartiri T et al. | α-Linolenic Acid, A Nutraceutical with Pleiotropic Properties That Targets Endogenous Neuroprotective Pathways to Protect against Organophosphate Nerve Agent-Induced Neuropathology. | 2015 | Molecules | pmid:26569216 |
Fu X et al. | Regulation of formation of volatile compounds of tea (Camellia sinensis) leaves by single light wavelength. | 2015 | Sci Rep | pmid:26567525 |
pmid:26561301 | ||||
pmid:26543039 | ||||
pmid:26526350 | ||||
Wright AM et al. | Effect of forage type with or without corn supplementation on animal performance, beef fatty acid composition, and palatability. | 2015 | J. Anim. Sci. | pmid:26523597 |
pmid:26521211 | ||||
pmid:26514651 | ||||
pmid:26512548 | ||||
Shi H et al. | Molecular mechanism of substrate specificity for delta 6 desaturase from Mortierella alpina and Micromonas pusilla. | 2015 | J. Lipid Res. | pmid:26486975 |
pmid:26471680 | ||||
Conde-Sieira M et al. | Hypothalamic fatty acid sensing in Senegalese sole (Solea senegalensis): response to long-chain saturated, monounsaturated, and polyunsaturated (n-3) fatty acids. | 2015 | Am. J. Physiol. Regul. Integr. Comp. Physiol. | pmid:26468264 |
pmid:26444910 | ||||
pmid:26440049 | ||||
Dodington DW et al. | Higher Intakes of Fruits and Vegetables, β-Carotene, Vitamin C, α-Tocopherol, EPA, and DHA Are Positively Associated with Periodontal Healing after Nonsurgical Periodontal Therapy in Nonsmokers but Not in Smokers. | 2015 | J. Nutr. | pmid:26423734 |
Dal Bello B et al. | Healthy yogurt fortified with n-3 fatty acids from vegetable sources. | 2015 | J. Dairy Sci. | pmid:26409962 |
Liao K et al. | Dietary Olive and Perilla Oils Affect Liver Mitochondrial DNA Methylation in Large Yellow Croakers. | 2015 | J. Nutr. | pmid:26400965 |
pmid:26399745 | ||||
pmid:26395388 | ||||
pmid:26387026 | ||||
pmid:26386148 | ||||
Kim KR et al. | Selective Production of 9R-Hydroxy-10E,12Z,15Z-Octadecatrienoic Acid from α-Linolenic Acid in Perilla Seed Oil Hydrolyzate by a Lipoxygenase from Nostoc Sp. SAG 25.82. | 2015 | PLoS ONE | pmid:26379279 |
pmid:26378118 | ||||
pmid:26364843 | ||||
pmid:26363928 | ||||
pmid:26350254 | ||||
Bobiński R and Mikulska M | The ins and outs of maternal-fetal fatty acid metabolism. | 2015 | Acta Biochim. Pol. | pmid:26345097 |
pmid:26328539 | ||||
Mansara PP et al. | Differential Ratios of Omega Fatty Acids (AA/EPA+DHA) Modulate Growth, Lipid Peroxidation and Expression of Tumor Regulatory MARBPs in Breast Cancer Cell Lines MCF7 and MDA-MB-231. | 2015 | PLoS ONE | pmid:26325577 |
pmid:26300470 | ||||
Imran M et al. | Impact of extrusion processing conditions on lipid peroxidation and storage stability of full-fat flaxseed meal. | 2015 | Lipids Health Dis | pmid:26286266 |
He J et al. | Correlation of polyunsaturated fatty acids with the cold adaptation of Rhodotorula glutinis. | 2015 | Yeast | pmid:26284451 |
Mason JK et al. | α-linolenic acid and docosahexaenoic acid, alone and combined with trastuzumab, reduce HER2-overexpressing breast cancer cell growth but differentially regulate HER2 signaling pathways. | 2015 | Lipids Health Dis | pmid:26282560 |
pmid:26280128 | ||||
pmid:26277770 | ||||
pmid:26271617 | ||||
pmid:26268732 | ||||
pmid:26264916 | ||||
pmid:26262674 | ||||
pmid:26249647 | ||||
Valenzuela R et al. | Modification of Docosahexaenoic Acid Composition of Milk from Nursing Women Who Received Alpha Linolenic Acid from Chia Oil during Gestation and Nursing. | 2015 | Nutrients | pmid:26247968 |
Pan P et al. | Black raspberries suppress colonic adenoma development in ApcMin/+ mice: relation to metabolite profiles. | 2015 | Carcinogenesis | pmid:26246425 |
Cole C et al. | Arum Palaestinum with isovanillin, linolenic acid and β-sitosterol inhibits prostate cancer spheroids and reduces the growth rate of prostate tumors in mice. | 2015 | BMC Complement Altern Med | pmid:26243305 |
Jubie S et al. | Isolation of methyl gamma linolenate from Spirulina platensis using flash chromatography and its apoptosis inducing effect. | 2015 | BMC Complement Altern Med | pmid:26238515 |
pmid:26189725 | ||||
pmid:26188993 | ||||
pmid:26187936 | ||||
Han H et al. | Flaxseed Oil Containing α -Linolenic Acid Ester of Plant Sterol Improved Atherosclerosis in ApoE Deficient Mice. | 2015 | Oxid Med Cell Longev | pmid:26180602 |
pmid:26174350 | ||||
Chen W et al. | Effect of flaxseed on the fatty acid profile of egg yolk and antioxidant status of their neonatal offspring in Huoyan geese. | 2015 | Animal | pmid:26173627 |
pmid:26169870 | ||||
pmid:26151719 | ||||
pmid:26142845 | ||||
pmid:26134471 | ||||
pmid:26125601 | ||||
pmid:26092420 | ||||
Sun L et al. | Coccomyxa Gloeobotrydiformis Improves Learning and Memory in Intrinsic Aging Rats. | 2015 | Int. J. Biol. Sci. | pmid:26078724 |
Folino A et al. | Alpha-linolenic acid protects against cardiac injury and remodelling induced by beta-adrenergic overstimulation. | 2015 | Food Funct | pmid:26068025 |
pmid:26044769 | ||||
Shang X et al. | Dietary α-Linolenic Acid and Total ω-3 Fatty Acids Are Inversely Associated with Abdominal Aortic Calcification in Older Women, but Not in Older Men. | 2015 | J. Nutr. | pmid:26041673 |
pmid:26041199 | ||||
pmid:26011096 | ||||
pmid:25997623 | ||||
Nieman DC et al. | No positive influence of ingesting chia seed oil on human running performance. | 2015 | Nutrients | pmid:25988762 |
pmid:25981324 | ||||
Shivashankar S and Sumathi M | Do seed VLCFAs trigger spongy tissue formation in Alphonso mango by inducing germination? | 2015 | J. Biosci. | pmid:25963264 |
pmid:25952888 | ||||
pmid:25951928 | ||||
pmid:25951778 | ||||
pmid:25935580 | ||||
pmid:25933532 | ||||
pmid:25933493 | ||||
Perumalsamy H et al. | Larvicidal activity and possible mode of action of four flavonoids and two fatty acids identified in Millettia pinnata seed toward three mosquito species. | 2015 | Parasit Vectors | pmid:25928224 |
pmid:25923344 | ||||
pmid:25920465 | ||||
Domenichiello AF et al. | Is docosahexaenoic acid synthesis from α-linolenic acid sufficient to supply the adult brain? | 2015 | Prog. Lipid Res. | pmid:25920364 |
pmid:25916258 | ||||
pmid:25906856 | ||||
Kawakami Y et al. | Flaxseed oil intake reduces serum small dense low-density lipoprotein concentrations in Japanese men: a randomized, double blind, crossover study. | 2015 | Nutr J | pmid:25896182 |
Hadjighassem M et al. | Oral consumption of α-linolenic acid increases serum BDNF levels in healthy adult humans. | 2015 | Nutr J | pmid:25889793 |
Shomonov-Wagner L et al. | Alpha linolenic acid in maternal diet halts the lipid disarray due to saturated fatty acids in the liver of mice offspring at weaning. | 2015 | Lipids Health Dis | pmid:25889505 |
pmid:25885355 | ||||
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