| MeSH term | MeSH ID | Detail |
|---|---|---|
| Hemolysis | D006461 | 131 associated lipids |
| Tuberculosis | D014376 | 20 associated lipids |
| Diabetes Mellitus | D003920 | 90 associated lipids |
| Adenocarcinoma | D000230 | 166 associated lipids |
| Breast Neoplasms | D001943 | 24 associated lipids |
| Neoplasms | D009369 | 13 associated lipids |
| Pain | D010146 | 64 associated lipids |
| Autoimmune Diseases | D001327 | 27 associated lipids |
| Lung Neoplasms | D008175 | 171 associated lipids |
| Pancreatic Neoplasms | D010190 | 77 associated lipids |
alpha-linolenic acid
Alpha-linolenic acid is a lipid of Fatty Acyls (FA) class. Alpha-linolenic acid is associated with abnormalities such as Coronary heart disease, abnormal fragmented structure, Arterial thrombosis and Subarachnoid Hemorrhage. The involved functions are known as Anabolism, Signal, Transcription, Genetic, Saturated and Regulation. Alpha-linolenic acid often locates in Blood, Body tissue, Plasma membrane, Hepatic and peroxisome. The associated genes with alpha-linolenic acid are FATE1 gene, volicitin, CYP2U1 gene, CYP1A2 gene and CYP2J2 gene. The related lipids are Fatty Acids, Dietary Fatty Acid, stearidonic acid and Fatty Acids, Nonesterified.
Cross Reference
Introduction
To understand associated biological information of alpha-linolenic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with alpha-linolenic acid?
alpha-linolenic acid is suspected in Coronary heart disease, Arterial thrombosis, Subarachnoid Hemorrhage and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with alpha-linolenic acid
PubChem Associated disorders and diseases
What pathways are associated with alpha-linolenic acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with alpha-linolenic acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with alpha-linolenic acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with alpha-linolenic acid?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with alpha-linolenic acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with alpha-linolenic acid?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with alpha-linolenic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Li T et al. | Defense priming by non-jasmonate producing fatty acids in maize (Zea mays). | 2016 | Plant Signal Behav | pmid:27763804 |
| Yamanaka N et al. | Alpha-Linolenic Acid-Enriched Diacylglycerol Oil Suppresses the Postprandial Serum Triglyceride Level-A Randomized, Double-Blind, Placebo-Controlled, Crossover Study. | 2016 | J. Nutr. Sci. Vitaminol. | pmid:28202845 |
| Kjær MA et al. | Regulation of the Omega-3 Fatty Acid Biosynthetic Pathway in Atlantic Salmon Hepatocytes. | 2016 | PLoS ONE | pmid:27973547 |
| Cao X et al. | Transcriptional Responses and Gentiopicroside Biosynthesis in Methyl Jasmonate-Treated Gentiana macrophylla Seedlings. | 2016 | PLoS ONE | pmid:27851826 |
| Wolters M et al. | Associations of Whole Blood n-3 and n-6 Polyunsaturated Fatty Acids with Blood Pressure in Children and Adolescents - Results from the IDEFICS/I.Family Cohort. | 2016 | PLoS ONE | pmid:27806134 |
| Demorest ZL et al. | Direct stacking of sequence-specific nuclease-induced mutations to produce high oleic and low linolenic soybean oil. | 2016 | BMC Plant Biol. | pmid:27733139 |
| Li XZ et al. | Dietary linseed oil with or without malate increases conjugated linoleic acid and oleic acid in milk fat and and gene expression in mammary gland and milk somatic cells of lactating goats. | 2016 | J. Anim. Sci. | pmid:27695785 |
| Lee Y et al. | Alpha-linolenic acid treatment during oocyte maturation enhances embryonic development by influencing mitogen-activated protein kinase activity and intraoocyte glutathione content in pigs. | 2016 | J. Anim. Sci. | pmid:27695771 |
| Chen T et al. | Perilla Oil Supplementation Ameliorates High-Fat/High-Cholesterol Diet Induced Nonalcoholic Fatty Liver Disease in Rats via Enhanced Fecal Cholesterol and Bile Acid Excretion. | 2016 | Biomed Res Int | pmid:27642591 |
| Tian Y et al. | Perilla Oil Has Similar Protective Effects of Fish Oil on High-Fat Diet-Induced Nonalcoholic Fatty Liver Disease and Gut Dysbiosis. | 2016 | Biomed Res Int | pmid:27051672 |
| Duscharla D et al. | Prostate Cancer Associated Lipid Signatures in Serum Studied by ESI-Tandem Mass Spectrometryas Potential New Biomarkers. | 2016 | PLoS ONE | pmid:26958841 |
| Minihane AM | Impact of Genotype on EPA and DHA Status and Responsiveness to Increased Intakes. | 2016 | Nutrients | pmid:26950146 |
| Carotenuto F et al. | Dietary Flaxseed Mitigates Impaired Skeletal Muscle Regeneration: in Vivo, in Vitro and in Silico Studies. | 2016 | Int J Med Sci | pmid:26941581 |
| Dote S et al. | Effects of Triacylglycerol Molecular Species on the Oxidation Behavior of Oils Containing α-Linolenic Acid. | 2016 | J Oleo Sci | pmid:26935948 |
| Heskey CE et al. | Adipose tissue α-linolenic acid is inversely associated with insulin resistance in adults. | 2016 | Am. J. Clin. Nutr. | pmid:26912497 |
| Zhao N et al. | α-Linolenic acid increases the G0/G1 switch gene 2 mRNA expression in peripheral blood mononuclear cells from obese patients: a pilot study. | 2016 | Lipids Health Dis | pmid:26912161 |
| Taha AY et al. | Threshold changes in rat brain docosahexaenoic acid incorporation and concentration following graded reductions in dietary alpha-linolenic acid. | 2016 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:26869088 |
| Moriyama R et al. | Long-chain unsaturated fatty acids reduce the transcriptional activity of the rat follicle-stimulating hormone β-subunit gene. | 2016 | J. Reprod. Dev. | pmid:26853521 |
| Deng Q et al. | Single frequency intake of α-linolenic acid rich phytosterol esters attenuates atherosclerosis risk factors in hamsters fed a high fat diet. | 2016 | Lipids Health Dis | pmid:26843021 |
| Gómez-Cortés P et al. | Novel characterisation of minor α-linolenic acid isomers in linseed oil by gas chromatography and covalent adduct chemical ionisation tandem mass spectrometry. | 2016 | Food Chem | pmid:26830571 |
| Sala-Vila A et al. | Dietary α-Linolenic Acid, Marine ω-3 Fatty Acids, and Mortality in a Population With High Fish Consumption: Findings From the PREvención con DIeta MEDiterránea (PREDIMED) Study. | 2016 | J Am Heart Assoc | pmid:26813890 |
| Garsetti M et al. | Fat composition of vegetable oil spreads and margarines in the USA in 2013: a national marketplace analysis. | 2016 | Int J Food Sci Nutr | pmid:27046021 |
| Wang JJ et al. | Two ω-3 FADs Are Associated with Peach Fruit Volatile Formation. | 2016 | Int J Mol Sci | pmid:27043529 |
| Hadjighassem M et al. | Oral consumption of α-linolenic acid increases serum BDNF levels in healthy adult humans. | 2015 | Nutr J | pmid:25889793 |
| Shomonov-Wagner L et al. | Alpha linolenic acid in maternal diet halts the lipid disarray due to saturated fatty acids in the liver of mice offspring at weaning. | 2015 | Lipids Health Dis | pmid:25889505 |
| Blondeau N et al. | Alpha-linolenic acid: an omega-3 fatty acid with neuroprotective properties-ready for use in the stroke clinic? | 2015 | Biomed Res Int | pmid:25789320 |
| Liu GJ et al. | Targeted Lipidomics Studies Reveal that Linolenic Acid Promotes Cotton Fiber Elongation by Activating Phosphatidylinositol and Phosphatidylinositol Monophosphate Biosynthesis. | 2015 | Mol Plant | pmid:25731673 |
| Veshkini A et al. | Effect of Linolenic acid during in vitro maturation of ovine oocytes: embryonic developmental potential and mRNA abundances of genes involved in apoptosis. | 2015 | J. Assist. Reprod. Genet. | pmid:25715790 |
| Perng W et al. | Alpha-linolenic acid (ALA) is inversely related to development of adiposity in school-age children. | 2015 | Eur J Clin Nutr | pmid:25271016 |
| Fu X et al. | Regulation of formation of volatile compounds of tea (Camellia sinensis) leaves by single light wavelength. | 2015 | Sci Rep | pmid:26567525 |
| Guichardant M et al. | Omega-3 polyunsaturated fatty acids and oxygenated metabolism in atherothrombosis. | 2015 | Biochim. Biophys. Acta | pmid:25263947 |
| Cespedes E et al. | Adipose tissue n-3 fatty acids and metabolic syndrome. | 2015 | Eur J Clin Nutr | pmid:25097001 |
| Koh AS et al. | The association between dietary omega-3 fatty acids and cardiovascular death: the Singapore Chinese Health Study. | 2015 | Eur J Prev Cardiol | pmid:24343844 |
| Keim SA and Branum AM | Dietary intake of polyunsaturated fatty acids and fish among US children 12-60 months of age. | 2015 | Matern Child Nutr | pmid:24034437 |
| Shivashankar S and Sumathi M | Do seed VLCFAs trigger spongy tissue formation in Alphonso mango by inducing germination? | 2015 | J. Biosci. | pmid:25963264 |
| Chen S et al. | Profiling of volatile compounds and associated gene expression and enzyme activity during fruit development in two cucumber cultivars. | 2015 | PLoS ONE | pmid:25799542 |
| Hernandez LR et al. | Effect of plant growth regulators on fatty acids composition in Jatropha curcas L. callus culture. | 2015 | J Oleo Sci | pmid:25757437 |
| Perumalsamy H et al. | Larvicidal activity and possible mode of action of four flavonoids and two fatty acids identified in Millettia pinnata seed toward three mosquito species. | 2015 | Parasit Vectors | pmid:25928224 |
| Conde-Sieira M et al. | Hypothalamic fatty acid sensing in Senegalese sole (Solea senegalensis): response to long-chain saturated, monounsaturated, and polyunsaturated (n-3) fatty acids. | 2015 | Am. J. Physiol. Regul. Integr. Comp. Physiol. | pmid:26468264 |
| Jung SW et al. | Mechanism of antibacterial activity of liposomal linolenic acid against Helicobacter pylori. | 2015 | PLoS ONE | pmid:25793403 |
| Wiest EF et al. | Association of serum aryl hydrocarbon receptor activity and RBC omega-3 polyunsaturated fatty acids with flow-mediated dilation in healthy, young Hispanic cigarette smokers. | 2015 | Toxicol. Lett. | pmid:25482063 |
| Lewinska A et al. | Fatty Acid Profile and Biological Activities of Linseed and Rapeseed Oils. | 2015 | Molecules | pmid:26703545 |
| Liu X et al. | APA-style human milk fat analogue from silkworm pupae oil: Enzymatic production and improving storage stability using alkyl caffeates. | 2015 | Sci Rep | pmid:26643045 |
| Piermartiri T et al. | α-Linolenic Acid, A Nutraceutical with Pleiotropic Properties That Targets Endogenous Neuroprotective Pathways to Protect against Organophosphate Nerve Agent-Induced Neuropathology. | 2015 | Molecules | pmid:26569216 |
| Wright AM et al. | Effect of forage type with or without corn supplementation on animal performance, beef fatty acid composition, and palatability. | 2015 | J. Anim. Sci. | pmid:26523597 |
| Shi H et al. | Molecular mechanism of substrate specificity for delta 6 desaturase from Mortierella alpina and Micromonas pusilla. | 2015 | J. Lipid Res. | pmid:26486975 |
| Shang X et al. | Dietary α-Linolenic Acid and Total ω-3 Fatty Acids Are Inversely Associated with Abdominal Aortic Calcification in Older Women, but Not in Older Men. | 2015 | J. Nutr. | pmid:26041673 |
| Nieman DC et al. | No positive influence of ingesting chia seed oil on human running performance. | 2015 | Nutrients | pmid:25988762 |
| Domenichiello AF et al. | Is docosahexaenoic acid synthesis from α-linolenic acid sufficient to supply the adult brain? | 2015 | Prog. Lipid Res. | pmid:25920364 |
| Kawakami Y et al. | Flaxseed oil intake reduces serum small dense low-density lipoprotein concentrations in Japanese men: a randomized, double blind, crossover study. | 2015 | Nutr J | pmid:25896182 |