alpha-linolenic acid

Alpha-linolenic acid is a lipid of Fatty Acyls (FA) class. Alpha-linolenic acid is associated with abnormalities such as Coronary heart disease, abnormal fragmented structure, Arterial thrombosis and Subarachnoid Hemorrhage. The involved functions are known as Anabolism, Signal, Transcription, Genetic, Saturated and Regulation. Alpha-linolenic acid often locates in Blood, Body tissue, Plasma membrane, Hepatic and peroxisome. The associated genes with alpha-linolenic acid are FATE1 gene, volicitin, CYP2U1 gene, CYP1A2 gene and CYP2J2 gene. The related lipids are Fatty Acids, Dietary Fatty Acid, stearidonic acid and Fatty Acids, Nonesterified.

Cross Reference

Introduction

To understand associated biological information of alpha-linolenic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with alpha-linolenic acid?

alpha-linolenic acid is suspected in Coronary heart disease, Arterial thrombosis, Subarachnoid Hemorrhage and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
Loading... please refresh the page if content is not showing up.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with alpha-linolenic acid

PubChem Associated disorders and diseases

What pathways are associated with alpha-linolenic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with alpha-linolenic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What functions are associated with alpha-linolenic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with alpha-linolenic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What genes are associated with alpha-linolenic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with alpha-linolenic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with alpha-linolenic acid

Download all related citations
Per page 10 20 50 100 | Total 2471
Authors Title Published Journal PubMed Link
Hadjighassem M et al. Oral consumption of α-linolenic acid increases serum BDNF levels in healthy adult humans. 2015 Nutr J pmid:25889793
Shomonov-Wagner L et al. Alpha linolenic acid in maternal diet halts the lipid disarray due to saturated fatty acids in the liver of mice offspring at weaning. 2015 Lipids Health Dis pmid:25889505
Blondeau N et al. Alpha-linolenic acid: an omega-3 fatty acid with neuroprotective properties-ready for use in the stroke clinic? 2015 Biomed Res Int pmid:25789320
Liu GJ et al. Targeted Lipidomics Studies Reveal that Linolenic Acid Promotes Cotton Fiber Elongation by Activating Phosphatidylinositol and Phosphatidylinositol Monophosphate Biosynthesis. 2015 Mol Plant pmid:25731673
Veshkini A et al. Effect of Linolenic acid during in vitro maturation of ovine oocytes: embryonic developmental potential and mRNA abundances of genes involved in apoptosis. 2015 J. Assist. Reprod. Genet. pmid:25715790
Bellaloui N and Mengistu A Effects of boron nutrition and water stress on nitrogen fixation, seed δ15N and δ13C dynamics, and seed composition in soybean cultivars differing in maturities. 2015 ScientificWorldJournal pmid:25667936
Fu X et al. Regulation of formation of volatile compounds of tea (Camellia sinensis) leaves by single light wavelength. 2015 Sci Rep pmid:26567525
Cespedes E et al. Adipose tissue n-3 fatty acids and metabolic syndrome. 2015 Eur J Clin Nutr pmid:25097001
Koh AS et al. The association between dietary omega-3 fatty acids and cardiovascular death: the Singapore Chinese Health Study. 2015 Eur J Prev Cardiol pmid:24343844
Keim SA and Branum AM Dietary intake of polyunsaturated fatty acids and fish among US children 12-60 months of age. 2015 Matern Child Nutr pmid:24034437
Shivashankar S and Sumathi M Do seed VLCFAs trigger spongy tissue formation in Alphonso mango by inducing germination? 2015 J. Biosci. pmid:25963264
Chen S et al. Profiling of volatile compounds and associated gene expression and enzyme activity during fruit development in two cucumber cultivars. 2015 PLoS ONE pmid:25799542
Yan S et al. Autoxidated linolenic acid inhibits aflatoxin biosynthesis in Aspergillus flavus via oxylipin species. 2015 Fungal Genet. Biol. pmid:25498164
Hernandez LR et al. Effect of plant growth regulators on fatty acids composition in Jatropha curcas L. callus culture. 2015 J Oleo Sci pmid:25757437
Clouard C et al. Dietary linoleic and α-linolenic acids affect anxiety-related responses and exploratory activity in growing pigs. 2015 J. Nutr. pmid:25644359
Perumalsamy H et al. Larvicidal activity and possible mode of action of four flavonoids and two fatty acids identified in Millettia pinnata seed toward three mosquito species. 2015 Parasit Vectors pmid:25928224
Conde-Sieira M et al. Hypothalamic fatty acid sensing in Senegalese sole (Solea senegalensis): response to long-chain saturated, monounsaturated, and polyunsaturated (n-3) fatty acids. 2015 Am. J. Physiol. Regul. Integr. Comp. Physiol. pmid:26468264
Jung SW et al. Mechanism of antibacterial activity of liposomal linolenic acid against Helicobacter pylori. 2015 PLoS ONE pmid:25793403
Wiest EF et al. Association of serum aryl hydrocarbon receptor activity and RBC omega-3 polyunsaturated fatty acids with flow-mediated dilation in healthy, young Hispanic cigarette smokers. 2015 Toxicol. Lett. pmid:25482063
Lewinska A et al. Fatty Acid Profile and Biological Activities of Linseed and Rapeseed Oils. 2015 Molecules pmid:26703545
Liu X et al. APA-style human milk fat analogue from silkworm pupae oil: Enzymatic production and improving storage stability using alkyl caffeates. 2015 Sci Rep pmid:26643045
Piermartiri T et al. α-Linolenic Acid, A Nutraceutical with Pleiotropic Properties That Targets Endogenous Neuroprotective Pathways to Protect against Organophosphate Nerve Agent-Induced Neuropathology. 2015 Molecules pmid:26569216
Wright AM et al. Effect of forage type with or without corn supplementation on animal performance, beef fatty acid composition, and palatability. 2015 J. Anim. Sci. pmid:26523597
Shi H et al. Molecular mechanism of substrate specificity for delta 6 desaturase from Mortierella alpina and Micromonas pusilla. 2015 J. Lipid Res. pmid:26486975
Dodington DW et al. Higher Intakes of Fruits and Vegetables, β-Carotene, Vitamin C, α-Tocopherol, EPA, and DHA Are Positively Associated with Periodontal Healing after Nonsurgical Periodontal Therapy in Nonsmokers but Not in Smokers. 2015 J. Nutr. pmid:26423734
Domenichiello AF et al. Is docosahexaenoic acid synthesis from α-linolenic acid sufficient to supply the adult brain? 2015 Prog. Lipid Res. pmid:25920364
Kawakami Y et al. Flaxseed oil intake reduces serum small dense low-density lipoprotein concentrations in Japanese men: a randomized, double blind, crossover study. 2015 Nutr J pmid:25896182
Salazar MO et al. A thin-layer chromatography autographic method for the detection of inhibitors of the Salmonella PhoP-PhoQ regulatory system. 2014 Mar-Apr Phytochem Anal pmid:24185747
Childs CE et al. Increased dietary α-linolenic acid has sex-specific effects upon eicosapentaenoic acid status in humans: re-examination of data from a randomised, placebo-controlled, parallel study. 2014 Nutr J pmid:25496415
Thamphiwatana S et al. In vivo treatment of Helicobacter pylori infection with liposomal linolenic acid reduces colonization and ameliorates inflammation. 2014 Proc. Natl. Acad. Sci. U.S.A. pmid:25422427
Alvarado-Gilis CA et al. Effects of feeding diets rich in α-linolenic acid and copper on performance, carcass characteristics, and fatty acid profiles of feedlot heifers. 2014 J. Anim. Sci. pmid:25414107
Baumgartner J et al. Providing male rats deficient in iron and n-3 fatty acids with iron and alpha-linolenic acid alone affects brain serotonin and cognition differently from combined provision. 2014 Lipids Health Dis pmid:24928171
Rajaram S Health benefits of plant-derived α-linolenic acid. 2014 Am. J. Clin. Nutr. pmid:24898228
Høstmark AT and Haug A The inverse association between relative abundances of oleic acid and arachidonic acid is related to alpha -linolenic acid. 2014 Lipids Health Dis pmid:24885640
He F et al. Perinatal α-linolenic acid availability alters the expression of genes related to memory and to epigenetic machinery, and the Mecp2 DNA methylation in the whole brain of mouse offspring. 2014 Int. J. Dev. Neurosci. pmid:24866706
Howard TD et al. DNA methylation in an enhancer region of the FADS cluster is associated with FADS activity in human liver. 2014 PLoS ONE pmid:24842322
Tian E et al. Detection and molecular characterization of two FAD3 genes controlling linolenic acid content and development of allele-specific markers in yellow mustard (Sinapis alba). 2014 PLoS ONE pmid:24823372
Zhu G et al. Enhanced production of docosahexaenoic acid in mammalian cells. 2014 PLoS ONE pmid:24788769
Enos RT et al. Reducing the dietary omega-6:omega-3 utilizing α-linolenic acid; not a sufficient therapy for attenuating high-fat-diet-induced obesity development nor related detrimental metabolic and adipose tissue inflammatory outcomes. 2014 PLoS ONE pmid:24733548
Papanikolaou Y et al. U.S. adults are not meeting recommended levels for fish and omega-3 fatty acid intake: results of an analysis using observational data from NHANES 2003-2008. 2014 Nutr J pmid:24694001
Qin G et al. Evolution of the aroma volatiles of pear fruits supplemented with fatty acid metabolic precursors. 2014 Molecules pmid:25474290
Herchi W et al. Flaxseed hull: Chemical composition and antioxidant activity during development. 2014 J Oleo Sci pmid:24919478
Matravadia S et al. Both linoleic and α-linolenic acid prevent insulin resistance but have divergent impacts on skeletal muscle mitochondrial bioenergetics in obese Zucker rats. 2014 Am. J. Physiol. Endocrinol. Metab. pmid:24844257
Hudson BD et al. The molecular basis of ligand interaction at free fatty acid receptor 4 (FFA4/GPR120). 2014 J. Biol. Chem. pmid:24860101
Gorina SS et al. Detection and molecular cloning of CYP74Q1 gene: identification of Ranunculus acris leaf divinyl ether synthase. 2014 Biochim. Biophys. Acta pmid:24863619
Vedtofte MS et al. Association between the intake of α-linolenic acid and the risk of CHD. 2014 Br. J. Nutr. pmid:24964401
Soto-Cerda BJ et al. Association mapping of seed quality traits using the Canadian flax (Linum usitatissimum L.) core collection. 2014 Theor. Appl. Genet. pmid:24463785
Petzinger C et al. Conversion of α-linolenic acid to long-chain omega-3 fatty acid derivatives and alterations of HDL density subfractions and plasma lipids with dietary polyunsaturated fatty acids in Monk parrots (Myiopsitta monachus). 2014 J Anim Physiol Anim Nutr (Berl) pmid:23600588
Yavin E et al. Metabolic conversion of intra-amniotically-injected deuterium-labeled essential fatty acids by fetal rats following maternal n-3 fatty acid deficiency. 2014 Biochim. Biophys. Acta pmid:24960100
Khodadoust S et al. Identification and determination of the fatty acid composition of Quercus brantii growing in southwestern Iran by GC-MS. 2014 Nat. Prod. Res. pmid:24499169