| MeSH term | MeSH ID | Detail |
|---|---|---|
| Hemolysis | D006461 | 131 associated lipids |
| Tuberculosis | D014376 | 20 associated lipids |
| Diabetes Mellitus | D003920 | 90 associated lipids |
| Adenocarcinoma | D000230 | 166 associated lipids |
| Breast Neoplasms | D001943 | 24 associated lipids |
| Neoplasms | D009369 | 13 associated lipids |
| Pain | D010146 | 64 associated lipids |
| Autoimmune Diseases | D001327 | 27 associated lipids |
| Lung Neoplasms | D008175 | 171 associated lipids |
| Pancreatic Neoplasms | D010190 | 77 associated lipids |
alpha-linolenic acid
Alpha-linolenic acid is a lipid of Fatty Acyls (FA) class. Alpha-linolenic acid is associated with abnormalities such as Coronary heart disease, abnormal fragmented structure, Arterial thrombosis and Subarachnoid Hemorrhage. The involved functions are known as Anabolism, Signal, Transcription, Genetic, Saturated and Regulation. Alpha-linolenic acid often locates in Blood, Body tissue, Plasma membrane, Hepatic and peroxisome. The associated genes with alpha-linolenic acid are FATE1 gene, volicitin, CYP2U1 gene, CYP1A2 gene and CYP2J2 gene. The related lipids are Fatty Acids, Dietary Fatty Acid, stearidonic acid and Fatty Acids, Nonesterified.
Cross Reference
Introduction
To understand associated biological information of alpha-linolenic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with alpha-linolenic acid?
alpha-linolenic acid is suspected in Coronary heart disease, Arterial thrombosis, Subarachnoid Hemorrhage and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with alpha-linolenic acid
PubChem Associated disorders and diseases
What pathways are associated with alpha-linolenic acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with alpha-linolenic acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with alpha-linolenic acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with alpha-linolenic acid?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with alpha-linolenic acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with alpha-linolenic acid?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with alpha-linolenic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Spector AA | Plasma free fatty acid and lipoproteins as sources of polyunsaturated fatty acid for the brain. | 2001 Apr-Jun | J. Mol. Neurosci. | pmid:11478370 |
| Cunnane SC et al. | NMR and isotope ratio mass spectrometry studies of in vivo uptake and metabolism of polyunsaturates by the developing rat brain. | 2001 Apr-Jun | J. Mol. Neurosci. | pmid:11478372 |
| Salem N et al. | Alterations in brain function after loss of docosahexaenoate due to dietary restriction of n-3 fatty acids. | 2001 Apr-Jun | J. Mol. Neurosci. | pmid:11478385 |
| Pawlosky RJ et al. | Physiological compartmental analysis of alpha-linolenic acid metabolism in adult humans. | 2001 | J. Lipid Res. | pmid:11483627 |
| Vancassel S et al. | Plasma fatty acid levels in autistic children. | 2001 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:11487301 |
| Hoffman DR et al. | Impaired synthesis of DHA in patients with X-linked retinitis pigmentosa. | 2001 | J. Lipid Res. | pmid:11518758 |
| Oomen CM et al. | alpha-Linolenic acid intake is not beneficially associated with 10-y risk of coronary artery disease incidence: the Zutphen Elderly Study. | 2001 | Am. J. Clin. Nutr. | pmid:11566643 |
| Randich A et al. | Jejunal or portal vein infusions of lipids increase hepatic vagal afferent activity. | 2001 | Neuroreport | pmid:11568645 |
| Harper CR and Jacobson TA | The fats of life: the role of omega-3 fatty acids in the prevention of coronary heart disease. | 2001 | Arch. Intern. Med. | pmid:11575974 |
| Pereira C et al. | The alpha-linolenic acid content of green vegetables commonly available in Australia. | 2001 | Int J Vitam Nutr Res | pmid:11582857 |
| Dobos G and Michalsen A | [Comment on the contribution by G. Keyser, "Are there reliable dietary recommendations for patients with rheumatoid arthritis?"]. | 2001 | Z Rheumatol | pmid:11584725 |
| Ikemoto A et al. | Reversibility of n-3 fatty acid deficiency-induced alterations of learning behavior in the rat: level of n-6 fatty acids as another critical factor. | 2001 | J. Lipid Res. | pmid:11590222 |
| Poumès-Ballihaut C et al. | Comparative bioavailability of dietary alpha-linolenic and docosahexaenoic acids in the growing rat. | 2001 | Lipids | pmid:11592729 |
| Agatha G et al. | Fatty acid composition of lymphocyte membrane phospholipids in children with acute leukemia. | 2001 | Cancer Lett. | pmid:11597788 |
| Bendall JG | Aroma compounds of fresh milk from New Zealand cows fed different diets. | 2001 | J. Agric. Food Chem. | pmid:11600029 |
| Kozachenko AI et al. | Characteristics of beta-carotene-induced inhibition of free radical oxidation of fatty acids with different degree of unsaturation. | 2001 Jul-Aug | Dokl. Biochem. Biophys. | pmid:11665681 |
| Mori T et al. | Beef tallow, but not perilla or corn oil, promotion of rat prostate and intestinal carcinogenesis by 3,2'-dimethyl-4-aminobiphenyl. | 2001 | Jpn. J. Cancer Res. | pmid:11676852 |
| Djoussé L et al. | Relation between dietary linolenic acid and coronary artery disease in the National Heart, Lung, and Blood Institute Family Heart Study. | 2001 | Am. J. Clin. Nutr. | pmid:11684529 |
| Xian M et al. | Production of gamma-linolenic acid by Mortierella isabellina grown on hexadecanol. | 2001 | Lett. Appl. Microbiol. | pmid:11696098 |
| Gibson RA et al. | Randomized trials with polyunsaturated fatty acid interventions in preterm and term infants: functional and clinical outcomes. | 2001 | Lipids | pmid:11724459 |
| Yamaguchi S et al. | Identification of a component that induces flowering of Lemna among the reaction products of alpha-ketol linolenic acid (FIF) and norepinephrine. | 2001 | Plant Cell Physiol. | pmid:11726704 |
| Glew RH et al. | Fatty acid composition of the milk lipids of Nepalese women: correlation between fatty acid composition of serum phospholipids and melting point. | 2001 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:11728165 |
| Contreras MA et al. | Chronic nutritional deprivation of n-3 alpha-linolenic acid does not affect n-6 arachidonic acid recycling within brain phospholipids of awake rats. | 2001 | J. Neurochem. | pmid:11739623 |
| Wróbel A | Decrease in 2,2,6,6-tetramethyl-piperidine-1-oxyl (TEMPO) EPR signal in peroxynitrite-treated erythrocyte membranes. | 2001 | Cell. Mol. Biol. Lett. | pmid:11753439 |
| Hatakeyama Y and Scarpace PJ | Transcriptional regulation of uncoupling protein-2 gene expression in L6 myotubes. | 2001 | Int. J. Obes. Relat. Metab. Disord. | pmid:11753581 |
| Omega-3 fatty acids in the treatment of depression. | 2001 | Harv Ment Health Lett | pmid:11770480 | |
| Tripathi AK et al. | A physiochemical mechanism of hemozoin (beta-hematin) synthesis by malaria parasite. | 2002 | Biochem. Biophys. Res. Commun. | pmid:11779214 |
| De Vriese SR et al. | Estimation of dietary fat intake of Belgian pregnant women. Comparison of two methods. | 2001 | Ann. Nutr. Metab. | pmid:11786650 |
| Schmelz EA et al. | The influence of intact-plant and excised-leaf bioassay designs on volicitin- and jasmonic acid-induced sesquiterpene volatile release in Zea mays. | 2001 | Planta | pmid:11800380 |
| Schwartz Z et al. | 1alpha,25(OH)2D3 regulates chondrocyte matrix vesicle protein kinase C (PKC) directly via G-protein-dependent mechanisms and indirectly via incorporation of PKC during matrix vesicle biogenesis. | 2002 | J. Biol. Chem. | pmid:11805100 |
| Bemelmans WJ et al. | Effect of an increased intake of alpha-linolenic acid and group nutritional education on cardiovascular risk factors: the Mediterranean Alpha-linolenic Enriched Groningen Dietary Intervention (MARGARIN) study. | 2002 | Am. J. Clin. Nutr. | pmid:11815311 |
| Xian M et al. | Production of linolenic acid by Mortierella isabellina grown on octadecanol. | 2002 | Curr. Microbiol. | pmid:11815860 |
| Good for the heart but not for the prostate? The alpha-linolenic acid dilemma. | 2002 | Harv Mens Health Watch | pmid:11823168 | |
| Kim HK and Choi H | Dietary alpha-linolenic acid lowers postprandial lipid levels with increase of eicosapentaenoic and docosahexaenoic acid contents in rat hepatic membrane. | 2001 | Lipids | pmid:11834085 |
| Son BW et al. | New galactolipids from the marine bacillariophycean microalga Nitzschia sp. | 2001 | Nat Prod Lett | pmid:11841113 |
| Cahoon EB et al. | Transgenic production of epoxy fatty acids by expression of a cytochrome P450 enzyme from Euphorbia lagascae seed. | 2002 | Plant Physiol. | pmid:11842164 |
| Brenna JT | Efficiency of conversion of alpha-linolenic acid to long chain n-3 fatty acids in man. | 2002 | Curr Opin Clin Nutr Metab Care | pmid:11844977 |
| Infante JP et al. | Straight-chain acyl-CoA oxidase knockout mouse accumulates extremely long chain fatty acids from alpha-linolenic acid: evidence for runaway carousel-type enzyme kinetics in peroxisomal beta-oxidation diseases. | 2002 | Mol. Genet. Metab. | pmid:11855929 |
| Tarpila S et al. | The effect of flaxseed supplementation in processed foods on serum fatty acids and enterolactone. | 2002 | Eur J Clin Nutr | pmid:11857049 |
| Lichtenstein AH et al. | Efficacy of a Therapeutic Lifestyle Change/Step 2 diet in moderately hypercholesterolemic middle-aged and elderly female and male subjects. | 2002 | J. Lipid Res. | pmid:11861668 |
| Futakuchi M et al. | Inhibition of conjugated fatty acids derived from safflower or perilla oil of induction and development of mammary tumors in rats induced by 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP). | 2002 | Cancer Lett. | pmid:11867197 |
| Sakurai T et al. | Short-term efficacy of enteral nutrition in the treatment of active Crohn's disease: a randomized, controlled trial comparing nutrient formulas. | 2002 Mar-Apr | JPEN J Parenter Enteral Nutr | pmid:11871742 |
| Manthey FA et al. | Processing and cooking effects on lipid content and stability of alpha-linolenic acid in spaghetti containing ground flaxseed. | 2002 | J. Agric. Food Chem. | pmid:11879055 |
| Kitajka K et al. | The role of n-3 polyunsaturated fatty acids in brain: modulation of rat brain gene expression by dietary n-3 fatty acids. | 2002 | Proc. Natl. Acad. Sci. U.S.A. | pmid:11880617 |
| De Lorgeril M and Salen P | Fish and N-3 fatty acids for the prevention and treatment of coronary heart disease: nutrition is not pharmacology. | 2002 | Am. J. Med. | pmid:11893373 |
| Pan J and Chung FL | Formation of cyclic deoxyguanosine adducts from omega-3 and omega-6 polyunsaturated fatty acids under oxidative conditions. | 2002 | Chem. Res. Toxicol. | pmid:11896684 |
| Yehuda S | Possible anti-Parkinson properties of N-(alpha-linolenoyl) tyrosine: a new molecule. | 2002 | Pharmacol. Biochem. Behav. | pmid:11900763 |
| Lee JY et al. | Antimicrobial synergistic effect of linolenic acid and monoglyceride against Bacillus cereus and Staphylococcus aureus. | 2002 | J. Agric. Food Chem. | pmid:11902977 |
| Carrié I et al. | Docosahexaenoic acid-rich phospholipid supplementation: effect on behavior, learning ability, and retinal function in control and n-3 polyunsaturated fatty acid deficient old mice. | 2002 | Nutr Neurosci | pmid:11929197 |
| Calder PC | omega 3 polyunsaturated fatty acids, inflammation and immunity. | 2001 | World Rev Nutr Diet | pmid:11935943 |