alpha-linolenic acid

Alpha-linolenic acid is a lipid of Fatty Acyls (FA) class. Alpha-linolenic acid is associated with abnormalities such as Coronary heart disease, abnormal fragmented structure, Arterial thrombosis and Subarachnoid Hemorrhage. The involved functions are known as Anabolism, Signal, Transcription, Genetic, Saturated and Regulation. Alpha-linolenic acid often locates in Blood, Body tissue, Plasma membrane, Hepatic and peroxisome. The associated genes with alpha-linolenic acid are FATE1 gene, volicitin, CYP2U1 gene, CYP1A2 gene and CYP2J2 gene. The related lipids are Fatty Acids, Dietary Fatty Acid, stearidonic acid and Fatty Acids, Nonesterified.

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Introduction

To understand associated biological information of alpha-linolenic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with alpha-linolenic acid?

alpha-linolenic acid is suspected in Coronary heart disease, Arterial thrombosis, Subarachnoid Hemorrhage and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with alpha-linolenic acid

PubChem Associated disorders and diseases

What pathways are associated with alpha-linolenic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

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What cellular locations are associated with alpha-linolenic acid?

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What functions are associated with alpha-linolenic acid?


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What lipids are associated with alpha-linolenic acid?

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What genes are associated with alpha-linolenic acid?

Related references are published most in these journals:


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What common seen animal models are associated with alpha-linolenic acid?

There are no associated biomedical information in the current reference collection.

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All references with alpha-linolenic acid

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Authors Title Published Journal PubMed Link
Sugasini D and Lokesh BR Uptake of α-linolenic acid and its conversion to long chain omega-3 fatty acids in rats fed microemulsions of linseed oil. 2012 Lipids pmid:23104428
Jung DM et al. Chemical properties and oxidative stability of perilla oils obtained from roasted perilla seeds as affected by extraction methods. 2012 J. Food Sci. pmid:23106331
Pereira H et al. Polyunsaturated Fatty acids of marine macroalgae: potential for nutritional and pharmaceutical applications. 2012 Mar Drugs pmid:23118712
Fang XL et al. Roles of α-linolenic acid on IGF-I secretion and GH/IGF system gene expression in porcine primary hepatocytes. 2012 Mol. Biol. Rep. pmid:23053988
He ML et al. Triticale dried distillers' grain increases alpha-linolenic acid in subcutaneous fat of beef cattle fed oilseeds. 2012 Lipids pmid:23054550
Garcia CV et al. Characterisation of bound volatile compounds of a low flavour kiwifruit species: Actinidia eriantha. 2012 Food Chem pmid:23107675
Beck JJ et al. Generation of the volatile spiroketals conophthorin and chalcogran by fungal spores on polyunsaturated fatty acids common to almonds and pistachios. 2012 J. Agric. Food Chem. pmid:23153034
Moodley R et al. Elemental composition and fatty acid profile of the edible fruits of Amatungula (Carissa macrocarpa) and impact of soil quality on chemical characteristics. 2012 Anal. Chim. Acta pmid:22632042
Lakshmanan V et al. Metabolomic analysis of patient plasma yields evidence of plant-like α-linolenic acid metabolism in Plasmodium falciparum. 2012 J. Infect. Dis. pmid:22566569
Saha SS et al. Synergistic effect of conjugated linolenic acid isomers against induced oxidative stress, inflammation and erythrocyte membrane disintegrity in rat model. 2012 Biochim. Biophys. Acta pmid:22967758
Shimpukade B et al. Discovery of a potent and selective GPR120 agonist. 2012 J. Med. Chem. pmid:22519963
Kim N and Choe E Singlet oxygen-related photooxidative stability and antioxidant changes of diacylglycerol-rich oil derived from mixture of olive and perilla oil. 2012 J. Food Sci. pmid:23057833
Georgiadi A et al. Detailed transcriptomics analysis of the effect of dietary fatty acids on gene expression in the heart. 2012 Physiol. Genomics pmid:22274564
de Batlle J et al. Association between Ω3 and Ω6 fatty acid intakes and serum inflammatory markers in COPD. 2012 J. Nutr. Biochem. pmid:21889886
He ML et al. Feeding flaxseed in grass hay and barley silage diets to beef cows increases alpha-linolenic acid and its biohydrogenation intermediates in subcutaneous fat. 2012 J. Anim. Sci. pmid:22274861
Sun T et al. Meat fatty acid and cholesterol level of free-range broilers fed on grasshoppers on alpine rangeland in the Tibetan Plateau. 2012 J. Sci. Food Agric. pmid:22318921
Deckelbaum RJ and Torrejon C The omega-3 fatty acid nutritional landscape: health benefits and sources. 2012 J. Nutr. pmid:22323763
Larsen MK et al. Fatty acid, tocopherol and carotenoid content in herbage and milk affected by sward composition and season of grazing. 2012 J. Sci. Food Agric. pmid:22337263
Angulo J et al. Nutritional evaluation of fruit and vegetable waste as feedstuff for diets of lactating Holstein cows. 2012 J. Environ. Manage. pmid:21784573
Pirat C et al. Targeting peroxisome proliferator-activated receptors (PPARs): development of modulators. 2012 J. Med. Chem. pmid:22260081
Huang T et al. Effect of n-3 polyunsaturated fatty acid on gene expression of the critical enzymes involved in homocysteine metabolism. 2012 Nutr J pmid:22260268
Gaquerel E et al. Nicotiana attenuata α-DIOXYGENASE1 through its production of 2-hydroxylinolenic acid is required for intact plant defense expression against attack from Manduca sexta larvae. 2012 New Phytol. pmid:22937952
Hughes BH et al. Oxidative stability and consumer acceptance of fish oil fortified nutrition bars. 2012 J. Food Sci. pmid:22957916
Aliani M et al. Effect of flax addition on the flavor profile and acceptability of bagels. 2012 J. Food Sci. pmid:22260132
Lerch S et al. Rapeseed or linseed in grass-based diets: effects on conjugated linoleic and conjugated linolenic acid isomers in milk fat from Holstein cows over 2 consecutive lactations. 2012 J. Dairy Sci. pmid:22999291
Janssen S et al. Sensing of fatty acids for octanoylation of ghrelin involves a gustatory G-protein. 2012 PLoS ONE pmid:22768248
Reinders I et al. Association of serum n-3 polyunsaturated fatty acids with C-reactive protein in men. 2012 Eur J Clin Nutr pmid:22113248
Kuhns EH et al. A lepidopteran aminoacylase (L-ACY-1) in Heliothis virescens (Lepidoptera: Noctuidae) gut lumen hydrolyzes fatty acid-amino acid conjugates, elicitors of plant defense. 2012 Insect Biochem. Mol. Biol. pmid:22056272
Mitra K et al. Studies of reaction variables for lipase-catalyzed production of alpha-linolenic acid enriched structured lipid and oxidative stability with antioxidants. 2012 J. Food Sci. pmid:22122200
Pal M and Ghosh M Prophylactic effect of α-linolenic acid and α-eleostearic acid against MeHg induced oxidative stress, DNA damage and structural changes in RBC membrane. 2012 Food Chem. Toxicol. pmid:22683484
Zhang G et al. Erythrocyte n-3 fatty acids and metabolic syndrome in middle-aged and older Chinese. 2012 J. Clin. Endocrinol. Metab. pmid:22456621
Ishida Y et al. Validation of thermally assisted hydrolysis and methylation-gas chromatography using a vertical microfurnace pyrolyzer for the compositional analysis of Fatty Acid components in microalgae. 2012 J. Agric. Food Chem. pmid:22458968
Mirmiran P et al. Association between interaction and ratio of ω-3 and ω-6 polyunsaturated fatty acid and the metabolic syndrome in adults. 2012 Nutrition pmid:22459553
Maqbool A et al. Relation between dietary fat intake type and serum fatty acid status in children with cystic fibrosis. 2012 J. Pediatr. Gastroenterol. Nutr. pmid:22699835
Du Q et al. Dairy fat blends high in α-linolenic acid are superior to n-3 fatty-acid-enriched palm oil blends for increasing DHA levels in the brains of young rats. 2012 J. Nutr. Biochem. pmid:22445803
Miyake Y et al. Dietary meat and fat intake and prevalence of rhinoconjunctivitis in pregnant Japanese women: baseline data from the Kyushu Okinawa Maternal and Child Health Study. 2012 Nutr J pmid:22449171
Nakamura YK et al. Modulation of oxidative stress by γ-glutamylcysteine (GGC) and conjugated linoleic acid (CLA) isomer mixture in human umbilical vein endothelial cells. 2012 Food Chem. Toxicol. pmid:22490668
Zhang LH et al. [Effects of alpha-linolenic acid on inflammation and oxidative stress in the diabetic rats]. 2012 Zhongguo Ying Yong Sheng Li Xue Za Zhi pmid:22493899
Fatima T et al. Fatty acid composition of developing sea buckthorn (Hippophae rhamnoides L.) berry and the transcriptome of the mature seed. 2012 PLoS ONE pmid:22558083
Luo ZM et al. A new norisoprenoid and other compounds from Fuzhuan brick tea. 2012 Molecules pmid:22430120
Ibrahim A et al. Dietary α-linolenic acid-rich formula reduces adhesion molecules in rats with experimental colitis. 2012 Nutrition pmid:22261574
Marei WF et al. Differential effects of linoleic and alpha-linolenic fatty acids on spatial and temporal mitochondrial distribution and activity in bovine oocytes. 2012 Reprod. Fertil. Dev. pmid:22697118
Passos PP et al. Dopaminergic cell populations of the rat substantia nigra are differentially affected by essential fatty acid dietary restriction over two generations. 2012 J. Chem. Neuroanat. pmid:22687395
Longvah T et al. Eri silkworm: a source of edible oil with a high content of α-linolenic acid and of significant nutritional value. 2012 J. Sci. Food Agric. pmid:22290445
Monteiro J et al. Menhaden oil, but not safflower or soybean oil, aids in restoring the polyunsaturated fatty acid profile in the novel delta-6-desaturase null mouse. 2012 Lipids Health Dis pmid:22642787
Castro LF et al. Functional desaturase Fads1 (Δ5) and Fads2 (Δ6) orthologues evolved before the origin of jawed vertebrates. 2012 PLoS ONE pmid:22384110
Pan H et al. Alpha-linolenic acid is a potent neuroprotective agent against soman-induced neuropathology. 2012 Neurotoxicology pmid:22884490
Huan M et al. In vivo anti-tumor activity of a new doxorubicin conjugate via α-linolenic acid. 2012 Biosci. Biotechnol. Biochem. pmid:22878199
Zhang G et al. [Effects of fatty acids on proliferation and differentiation of myoblast]. 2012 Wei Sheng Yan Jiu pmid:23424861
Santos FS et al. Status of cis and trans fatty acids in Brazilian adolescent mothers and their newborns. 2012 J Pediatr Adolesc Gynecol pmid:22840939