1,2-Dioleoyl-sn-glycerol

1,2-Dioleoyl-sn-glycerol is a lipid of Glycerolipids (GL) class. 1,2-dioleoyl-sn-glycerol is associated with abnormalities such as SAPOSIN D (disease) and Exanthema. The involved functions are known as Energy Transfer, Increased Sensitivy, Chelating Activity [MoA], protein kinase C activity and Phosphorylation. 1,2-dioleoyl-sn-glycerol often locates in vesicle, Tissue membrane, Membrane, viral nucleocapsid location and Protoplasm. The associated genes with 1,2-Dioleoyl-sn-glycerol are SIGLEC12 gene, Genome, RNF7 gene, FANCL gene and TNFRSF11B gene. The related lipids are Unilamellar Vesicles, diolein, Phosphatidylserines, Fatty Acids and monoolein.

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Introduction

To understand associated biological information of 1,2-Dioleoyl-sn-glycerol, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with 1,2-Dioleoyl-sn-glycerol?

1,2-Dioleoyl-sn-glycerol is suspected in SAPOSIN D (disease), Exanthema and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with 1,2-Dioleoyl-sn-glycerol

MeSH term MeSH ID Detail
Body Weight D001835 333 associated lipids
Cell Transformation, Neoplastic D002471 126 associated lipids
Anemia, Sickle Cell D000755 34 associated lipids
Total 3

PubChem Associated disorders and diseases

What pathways are associated with 1,2-Dioleoyl-sn-glycerol

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with 1,2-Dioleoyl-sn-glycerol?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with 1,2-Dioleoyl-sn-glycerol?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with 1,2-Dioleoyl-sn-glycerol?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with 1,2-Dioleoyl-sn-glycerol?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with 1,2-Dioleoyl-sn-glycerol?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with 1,2-Dioleoyl-sn-glycerol

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Authors Title Published Journal PubMed Link
pmid:
BAER E and BUCHNEA D Synthesis of unsaturated alpha, beta-diglycerides. I. D-alpha, beta-diolein and L-alpha, beta-diolein. 1958 J. Biol. Chem. pmid:13502413
KRABISCH L and BORGSTROEM B SYNTHESIS OF RACEMIC 1,2-DIOLEIN. 1965 J. Lipid Res. pmid:14280463
Arnaud J et al. In vitro effect of adrenocorticotrophic hormone on the pH profile of tri- and diester lipase activities from rat brain. 1980 Biochim. Biophys. Acta pmid:6245706
Sasaki N et al. Studies on CDP-choline:1,2-diacylglycerol cholinephosphotransferase activity in rat arterial wall. 1982 Atherosclerosis pmid:6288057
Sahai A et al. Activation of calcium and phospholipid-dependent protein kinase by epidermal growth factor (EGF) in A431 cells: attenuation by 12-0-tetradecanoylphorbol-13-acetate (TPA). 1982 Biochem. Biophys. Res. Commun. pmid:6220697
Kiss Z and Mhina V Rat liver plasma membranes contain a lipid-dependent protein kinase activity. 1982 FEBS Lett. pmid:6816631
Wise BC and Kuo JF Modes of inhibition by acylcarnitines, adriamycin and trifluoperazine of cardiac phospholipid-sensitive calcium-dependent protein kinase. 1983 Biochem. Pharmacol. pmid:6847716
Compton SK et al. Hydrolysis of neutral lipids and phospholipids in the isolated, perfused rat lung. 1984 Biochim. Biophys. Acta pmid:6466697
Coolican SA and Hathaway DR Effect of L-alpha-phosphatidylinositol on a vascular smooth muscle Ca2+-dependent protease. Reduction of the Ca2+ requirement for autolysis. 1984 J. Biol. Chem. pmid:6090440
Okazaki T et al. The identification and characterization of protein kinase C activity in fetal membranes. 1984 Arch. Biochem. Biophys. pmid:6230994
Nishikawa M et al. Protein kinase C modulates in vitro phosphorylation of the smooth muscle heavy meromyosin by myosin light chain kinase. 1984 J. Biol. Chem. pmid:6235218
Rando RR and Young N The stereospecific activation of protein kinase C. 1984 Biochem. Biophys. Res. Commun. pmid:6235812
Kapoor CL and Chader GJ Endogenous phosphorylation of retinal photoreceptor outer segment proteins by calcium phospholipid-dependent protein kinase. 1984 Biochem. Biophys. Res. Commun. pmid:6236809
Blumberg PM et al. Mechanism of action of the phorbol ester tumor promoters: specific receptors for lipophilic ligands. 1984 Biochem. Pharmacol. pmid:6324806
Heyworth CM et al. The phorbol ester, TPA inhibits glucagon-stimulated adenylate cyclase activity. 1984 FEBS Lett. pmid:6327375
Hubinont CJ et al. Activation of protein kinase C by a tumor-promoting phorbol ester in pancreatic islets. 1984 FEBS Lett. pmid:6327381
Ganong BR and Bell RM Transmembrane movement of phosphatidylglycerol and diacylglycerol sulfhydryl analogues. 1984 Biochemistry pmid:6498172
Smith JD Differential selectivity of cholinephosphotransferase and ethanolaminephosphotransferase of Tetrahymena for diacylglycerol and alkylacylglycerol. 1985 J. Biol. Chem. pmid:2982806
Orita Y et al. Calcium-activated, phospholipid-dependent protein kinase in cultured rat mesangial cells. 1985 FEBS Lett. pmid:2996937
Shirai K et al. Human plasma carboxyl esterase-catalyzed triolein hydrolysis. Existence of promoting factor in serum. 1985 J. Biol. Chem. pmid:3988750
Sharkey NA and Blumberg PM Kinetic evidence that 1,2-diolein inhibits phorbol ester binding to protein kinase C via a competitive mechanism. 1985 Biochem. Biophys. Res. Commun. pmid:3936500
Lin T The role of calcium/phospholipid-dependent protein kinase in Leydig cell steroidogenesis. 1985 Endocrinology pmid:2988910
Beg ZH et al. Phosphorylation of hepatic 3-hydroxy-3-methylglutaryl coenzyme A reductase and modulation of its enzymic activity by calcium-activated and phospholipid-dependent protein kinase. 1985 J. Biol. Chem. pmid:3155737
Summers TA and Creutz CE Phosphorylation of a chromaffin granule-binding protein by protein kinase C. 1985 J. Biol. Chem. pmid:3156130
Brasseur R et al. Structural analogies between protein kinase C activators. 1985 Biochem. Biophys. Res. Commun. pmid:3157375
Kimura K et al. Phosphorylation of high mobility group 1 protein by phospholipid-sensitive Ca2+-dependent protein kinase from pig testis. 1985 Biochem. J. pmid:3158310
Brocklehurst KW et al. Characterization of protein kinase C and its role in catecholamine secretion from bovine adrenal-medullary cells. 1985 Biochem. J. pmid:3159383
Omri B and Pavlovic-Hournac M Protein kinase C activity in experimentally developed and regressed rat thyroid goitres. 1985 Mol. Cell. Endocrinol. pmid:3159607
Friedman Y et al. Diacylglycerol-activated, calcium/phospholipid-dependent protein kinase (protein kinase C) activity in bovine thyroid. 1985 Biochem. Biophys. Res. Commun. pmid:3161511
Carrascosa JM and Wieland OH Evidence that (a) serine specific protein kinase(s) different from protein kinase C is responsible for the insulin-stimulated actin phosphorylation by placental membrane. 1986 FEBS Lett. pmid:2940115
Messing RO et al. Inhibition of calcium flux and calcium channel antagonist binding in the PC12 neural cell line by phorbol esters and protein kinase C. 1986 Biochem. Biophys. Res. Commun. pmid:2941013
Christiansen NO et al. Ca2+ and phorbol ester activation of protein kinase C at intracellular Ca2+ concentrations and the effect of TMB-8. 1986 Biochim. Biophys. Acta pmid:3011108
Galdieri M et al. Calcium-, phospholipid-dependent protein kinase activity of cultured rat Sertoli cells and its modifications by vitamin A. 1986 Mol. Cell. Endocrinol. pmid:3100359
Kiss Z and Luo YA Phorbol ester and 1,2-diolein are not fully equivalent activators of protein kinase C in respect to phosphorylation of membrane proteins in vitro. 1986 FEBS Lett. pmid:3082674
Liles WC et al. Activation of protein kinase C induces rapid internalization and subsequent degradation of muscarinic acetylcholine receptors in neuroblastoma cells. 1986 J. Biol. Chem. pmid:3082882
Hoshijima M et al. Formation of a phorbol ester-binding fragment from protein kinase C by proteolytic digestion. 1986 Cancer Res. pmid:3084081
Velasco G et al. Protein kinase C from small intestine epithelial cells. 1986 Biochem. Biophys. Res. Commun. pmid:3768005
Gonzatti-Haces MI and Traugh JA Ca2+-independent activation of protease-activated kinase II by phospholipids/diolein and comparison with the Ca2+/phospholipid-dependent protein kinase. 1986 J. Biol. Chem. pmid:3771573
Caratsch CG et al. Postsynaptic effects of the phorbol ester TPA on frog end-plates. 1986 Pflugers Arch. pmid:3774508
Nikolopoulou M et al. Autophosphorylation of boar sperm membranes. 1986 Biochem. Int. pmid:3741445
Kumar R and Holian O Retinoid effect on calcium, phospholipid-dependent protein kinase from mouse skin. 1986 J. Invest. Dermatol. pmid:3745956
Hermon J et al. Phospholipid-dependent Ca2+-activated protein kinase (C-kinase) in the pituitary: further characterization and endogenous redistribution. 1986 Mol. Cell. Endocrinol. pmid:3758474
Slack BE et al. Inositol-1,4,5-trisphosphate injection mimics fertilization potentials in sea urchin eggs. 1986 Am. J. Physiol. pmid:3485384
Hannun YA et al. Sphingosine inhibition of protein kinase C activity and of phorbol dibutyrate binding in vitro and in human platelets. 1986 J. Biol. Chem. pmid:3462188
Gopalakrishna R et al. Factors influencing chelator-stable, detergent-extractable, phorbol diester-induced membrane association of protein kinase C. Differences between Ca2+-induced and phorbol ester-stabilized membrane bindings of protein kinase C. 1986 J. Biol. Chem. pmid:3465725
Lynch CJ et al. The hormone-sensitive hepatic Na+-pump. Evidence for regulation by diacylglycerol and tumor promoters. 1986 J. Biol. Chem. pmid:3021743
Christiansen NO and Juhl H Purification and properties of protein kinase C from bovine polymorphonuclear leucocytes. 1986 Biochim. Biophys. Acta pmid:3947678
Murray N and Steck AJ Activation of myelin protein kinase by diacylglycerol and 4 beta-phorbol 12-myristate 13-acetate. 1986 J. Neurochem. pmid:2420938
Cheng KH and Hui SW Correlation between bilayer destabilization and activity enhancement by diacylglycerols in reconstituted Ca-ATPase vesicles. 1986 Arch. Biochem. Biophys. pmid:2936304