1,2-Dioleoyl-sn-glycerol

1,2-Dioleoyl-sn-glycerol is a lipid of Glycerolipids (GL) class. 1,2-dioleoyl-sn-glycerol is associated with abnormalities such as SAPOSIN D (disease) and Exanthema. The involved functions are known as Energy Transfer, Increased Sensitivy, Chelating Activity [MoA], protein kinase C activity and Phosphorylation. 1,2-dioleoyl-sn-glycerol often locates in vesicle, Tissue membrane, Membrane, viral nucleocapsid location and Protoplasm. The associated genes with 1,2-Dioleoyl-sn-glycerol are SIGLEC12 gene, Genome, RNF7 gene, FANCL gene and TNFRSF11B gene. The related lipids are Unilamellar Vesicles, diolein, Phosphatidylserines, Fatty Acids and monoolein.

Cross Reference

Introduction

To understand associated biological information of 1,2-Dioleoyl-sn-glycerol, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with 1,2-Dioleoyl-sn-glycerol?

1,2-Dioleoyl-sn-glycerol is suspected in SAPOSIN D (disease), Exanthema and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with 1,2-Dioleoyl-sn-glycerol

MeSH term MeSH ID Detail
Body Weight D001835 333 associated lipids
Cell Transformation, Neoplastic D002471 126 associated lipids
Anemia, Sickle Cell D000755 34 associated lipids
Total 3

PubChem Associated disorders and diseases

What pathways are associated with 1,2-Dioleoyl-sn-glycerol

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with 1,2-Dioleoyl-sn-glycerol?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with 1,2-Dioleoyl-sn-glycerol?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with 1,2-Dioleoyl-sn-glycerol?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with 1,2-Dioleoyl-sn-glycerol?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with 1,2-Dioleoyl-sn-glycerol?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with 1,2-Dioleoyl-sn-glycerol

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Authors Title Published Journal PubMed Link
Shi L Structural Identification and Systematic Comparison of Phorbol Ester, Dioleoylglycerol, Alcohol and Sevoflurane Binding Sites in PKCδ C1A Domain. 2018 Protein J. pmid:30251087
Wadsäter M et al. The lipolytic degradation of highly structured cubic micellar nanoparticles of soy phosphatidylcholine and glycerol dioleate by phospholipase A and triacylglycerol lipase. 2018 Chem. Phys. Lipids pmid:29132829
Xu Y et al. Characterization of a Liquid Crystal System for Sustained Release of a Peptide BMS-686117. 2018 AAPS PharmSciTech pmid:28741139
Nagy-Szakal D et al. Insights into myalgic encephalomyelitis/chronic fatigue syndrome phenotypes through comprehensive metabolomics. 2018 Sci Rep pmid:29968805
Tu-Sekine B and Raben DM Measuring Diacylglycerol Kinase-θ Activity and Binding. 2017 Meth. Enzymol. pmid:28063493
Accardo A et al. Diolein Based Nanostructures as Targeted Theranostics. 2016 J Biomed Nanotechnol pmid:27305827
Zhang L et al. Ionic Hydrogen Bonds and Lipid Packing Defects Determine the Binding Orientation and Insertion Depth of RecA on Multicomponent Lipid Bilayers. 2016 J Phys Chem B pmid:27095675
Alekseeva A et al. Interactions of antitumour Sialyl Lewis X liposomes with vascular endothelial cells. 2015 Biochim. Biophys. Acta pmid:25646577
Linkevičiūtė A et al. Preparation and characterization of quercetin-loaded lipid liquid crystalline systems. 2015 Colloids Surf B Biointerfaces pmid:25701115
Wadsäter M et al. Structural effects of the dispersing agent polysorbate 80 on liquid crystalline nanoparticles of soy phosphatidylcholine and glycerol dioleate. 2015 Soft Matter pmid:25531822
Manca ML et al. Development of novel diolein-niosomes for cutaneous delivery of tretinoin: influence of formulation and in vitro assessment. 2014 Int J Pharm pmid:25455770
Wadsäter M et al. Formation of highly structured cubic micellar lipid nanoparticles of soy phosphatidylcholine and glycerol dioleate and their degradation by triacylglycerol lipase. 2014 ACS Appl Mater Interfaces pmid:24779728
Iizuka Y et al. Improvement and evaluation of a 1,2-dioleoylglycerol method for measuring pancreatic lipase catalytic activity in serum. 2014 Clin. Chem. Lab. Med. pmid:24731955
Barauskas J et al. Bioadhesive lipid compositions: self-assembly structures, functionality, and medical applications. 2014 Mol. Pharm. pmid:24422996
Kamo T et al. Lateral pressure change on phase transitions of phosphatidylcholine/diolein mixed membranes. 2013 Colloids Surf B Biointerfaces pmid:23298597
Iizuka Y et al. 1,2-Dioleoylglycerol method for pancreatic lipase catalytic activity in serum. 2012 Clin. Chem. Lab. Med. pmid:22126376
Takai Y et al. Unsaturated diacylglycerol as a possible messenger for the activation of calcium-activated, phospholipid-dependent protein kinase system. 1979. 2012 Biochem. Biophys. Res. Commun. pmid:22925676
Shimizu M et al. Elimination of glycidyl palmitate in diolein by treatment with activated bleaching earth. 2012 J Oleo Sci pmid:22188803
Chang DP et al. Adsorption of lipid liquid crystalline nanoparticles: effects of particle composition, internal structure, and phase behavior. 2012 Langmuir pmid:22725977
Pérez-Lara A et al. The membrane binding kinetics of full-length PKCα is determined by membrane lipid composition. 2012 Biochim. Biophys. Acta pmid:22842589
Li S et al. Full utilization of a mass spectrometer using on-demand sharing with multiple LC units. 2012 J Mass Spectrom pmid:22899517
Zeng N et al. Lipid-based liquid crystalline nanoparticles as oral drug delivery vehicles for poorly water-soluble drugs: cellular interaction and in vivo absorption. 2012 Int J Nanomedicine pmid:22888230
Shin J et al. Acid-labile mPEG-vinyl ether-1,2-dioleylglycerol lipids with tunable pH sensitivity: synthesis and structural effects on hydrolysis rates, DOPE liposome release performance, and pharmacokinetics. 2012 Mol. Pharm. pmid:23030381
Totani N et al. Ferulic acid esters and weight-loss promoting effects in rats. 2012 J Oleo Sci pmid:22687778
González-Rubio P et al. Amphipathic-Lipid-Packing-Sensor interactions with lipids assessed by atomistic molecular dynamics. 2011 Biochim. Biophys. Acta pmid:21600869
Wang ZF et al. Microchip electrophoresis of bacteria using lipid-based liquid crystalline nanoparticles. 2011 J Chromatogr A pmid:21968347
Laszlo JA et al. Feruloyl dioleoylglycerol antioxidant capacity in phospholipid vesicles. 2010 J. Agric. Food Chem. pmid:20394373
Rodriguez JA et al. In vitro stereoselective hydrolysis of diacylglycerols by hormone-sensitive lipase. 2010 Biochim. Biophys. Acta pmid:19800417
Gauger DR et al. A spectroscopic method to estimate the binding potency of amphiphile assemblies. 2010 Anal Bioanal Chem pmid:20635078
Rosenbaum E et al. A characterisation study on the application of inverted lyotropic phases for subcutaneous drug release. 2010 Int J Pharm pmid:20026201
Majhi A et al. Binding of curcumin and its long chain derivatives to the activator binding domain of novel protein kinase C. 2010 Bioorg. Med. Chem. pmid:20100661
Heier C et al. Identification of Yju3p as functional orthologue of mammalian monoglyceride lipase in the yeast Saccharomycescerevisiae. 2010 Biochim. Biophys. Acta pmid:20554061
Kuznetsova NR et al. [The influence of carbohydrate ligands on the cytotoxicity of liposomes bearing a methotrexate-diglyceride conjugate in human acute leukemia cell cultures]. 2009 Jul-Aug Bioorg. Khim. pmid:19928057
Shearman GC et al. A 3-D hexagonal inverse micellar lyotropic phase. 2009 J. Am. Chem. Soc. pmid:19146371
Talhari DT et al. Interaction of a C-terminal peptide of Bos taurus diacylglycerol acyltransferase 1 with model membranes. 2009 Biochim. Biophys. Acta pmid:19664998
Sánchez-Bautista S et al. A comparison of the membrane binding properties of C1B domains of PKCgamma, PKCdelta, and PKCepsilon. 2009 Biophys. J. pmid:19413969
Mitchell DA et al. Determination of the quantitative stereoselectivity fingerprint of lipases during hydrolysis of a prochiral triacylglycerol. 2008 J. Biotechnol. pmid:18455825
Epand RM et al. Substrate chirality and specificity of diacylglycerol kinases and the multisubstrate lipid kinase. 2007 Biochemistry pmid:18004883
Tu-Sekine B et al. Modulation of diacylglycerol kinase theta activity by alpha-thrombin and phospholipids. 2007 Biochemistry pmid:17223715
Rübe A et al. Monitoring of in vitro fat digestion by electron paramagnetic resonance spectroscopy. 2006 Pharm. Res. pmid:16900409
Barauskas J et al. "Sponge" nanoparticle dispersions in aqueous mixtures of diglycerol monooleate, glycerol dioleate, and polysorbate 80. 2006 Langmuir pmid:16800694
Fowler CJ and Tiger G Cyclooxygenation of the arachidonoyl side chain of 1-arachidonoylglycerol and related compounds block their ability to prevent anandamide and 2-oleoylglycerol metabolism by rat brain in vitro. 2005 Biochem. Pharmacol. pmid:15794945
Piyatheerawong W et al. Direct separation of regio- and enantiomeric isomers of diacylglycerols by a tandem column high-performance liquid chromatography. 2005 J Chromatogr A pmid:15830930
Gómez-Merino FC et al. Arabidopsis AtDGK7, the smallest member of plant diacylglycerol kinases (DGKs), displays unique biochemical features and saturates at low substrate concentration: the DGK inhibitor R59022 differentially affects AtDGK2 and AtDGK7 activity in vitro and alters plant growth and development. 2005 J. Biol. Chem. pmid:16081412
Johnsson M et al. Aqueous phase behavior and dispersed nanoparticles of diglycerol monooleate/glycerol dioleate mixtures. 2005 Langmuir pmid:15896065
Vodovozova EL et al. [Synthesis of a lipid derivative of the antitumor agent methotrexate]. 2004 Nov-Dec Bioorg. Khim. pmid:15586820
Gómez-Merino FC et al. AtDGK2, a novel diacylglycerol kinase from Arabidopsis thaliana, phosphorylates 1-stearoyl-2-arachidonoyl-sn-glycerol and 1,2-dioleoyl-sn-glycerol and exhibits cold-inducible gene expression. 2004 J. Biol. Chem. pmid:14665624
Jenkins CM et al. Identification, cloning, expression, and purification of three novel human calcium-independent phospholipase A2 family members possessing triacylglycerol lipase and acylglycerol transacylase activities. 2004 J. Biol. Chem. pmid:15364929
Andoh T et al. PKC-independent inhibition of neuronal nicotinic acetylcholine receptors by diacylglycerol. 2004 Brain Res. pmid:15196975
Bojar RA et al. The effect of lipids on the adherence of axillary aerobic coryneform bacteria. 2004 Lett. Appl. Microbiol. pmid:15130141