1,2-Dioleoyl-sn-glycerol

1,2-Dioleoyl-sn-glycerol is a lipid of Glycerolipids (GL) class. 1,2-dioleoyl-sn-glycerol is associated with abnormalities such as SAPOSIN D (disease) and Exanthema. The involved functions are known as Energy Transfer, Increased Sensitivy, Chelating Activity [MoA], protein kinase C activity and Phosphorylation. 1,2-dioleoyl-sn-glycerol often locates in vesicle, Tissue membrane, Membrane, viral nucleocapsid location and Protoplasm. The associated genes with 1,2-Dioleoyl-sn-glycerol are SIGLEC12 gene, Genome, RNF7 gene, FANCL gene and TNFRSF11B gene. The related lipids are Unilamellar Vesicles, diolein, Phosphatidylserines, Fatty Acids and monoolein.

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Introduction

To understand associated biological information of 1,2-Dioleoyl-sn-glycerol, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with 1,2-Dioleoyl-sn-glycerol?

1,2-Dioleoyl-sn-glycerol is suspected in SAPOSIN D (disease), Exanthema and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with 1,2-Dioleoyl-sn-glycerol

MeSH term MeSH ID Detail
Body Weight D001835 333 associated lipids
Cell Transformation, Neoplastic D002471 126 associated lipids
Anemia, Sickle Cell D000755 34 associated lipids
Total 3

PubChem Associated disorders and diseases

What pathways are associated with 1,2-Dioleoyl-sn-glycerol

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with 1,2-Dioleoyl-sn-glycerol?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with 1,2-Dioleoyl-sn-glycerol?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with 1,2-Dioleoyl-sn-glycerol?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with 1,2-Dioleoyl-sn-glycerol?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with 1,2-Dioleoyl-sn-glycerol?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with 1,2-Dioleoyl-sn-glycerol

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Authors Title Published Journal PubMed Link
Gosselin MA et al. Incorporation of reversibly cross-linked polyplexes into LPDII vectors for gene delivery. 2002 Sep-Oct Bioconjug. Chem. pmid:12236787
Sassa T and Miwa J Purification and characterization of protein kinase C from the nematode Caenorhabditis elegans. 1992 Biochem. J. pmid:1311553
Hayashi T et al. Synergistic stimulating effect between cyclic AMP and phorbol ester on plasminogen activator inhibitor type 2 production in human promyelocytic leukemia cell line PL-21. 1992 Biochim. Biophys. Acta pmid:1313698
Olivier M et al. Defective stimulus-response coupling in human monocytes infected with Leishmania donovani is associated with altered activation and translocation of protein kinase C. 1992 Proc. Natl. Acad. Sci. U.S.A. pmid:1323839
Maizels ET et al. Estrogen modulates Ca(2+)-independent lipid-stimulated kinase in the rabbit corpus luteum of pseudopregnancy. Identification of luteal estrogen-modulated lipid-stimulated kinase as protein kinase C delta. 1992 J. Biol. Chem. pmid:1324921
Haeffner EW and Wittmann U Ca2+ and partly GTP gamma S-dependent particulate phospholipase C hydrolyzing phosphatidylinositol 4-phosphate and phosphatidylinositol 4,5-bisphosphate is inhibited by diacyl(acyl-acetyl) glycerols. 1992 J Lipid Mediat pmid:1334719
BAER E and BUCHNEA D Synthesis of unsaturated alpha, beta-diglycerides. I. D-alpha, beta-diolein and L-alpha, beta-diolein. 1958 J. Biol. Chem. pmid:13502413
Bradbury NA and Bridges RJ Endocytosis is regulated by protein kinase A, but not protein kinase C in a secretory epithelial cell line. 1992 Biochem. Biophys. Res. Commun. pmid:1375455
Tsujita T and Okuda H Effect of diolein on hydrolysis of phosphatidylcholine by phospholipase C from Clostridium perfringens. 1992 J. Biochem. pmid:1400264
Patel JM et al. Oxidant and angiotensin II-induced subcellular translocation of protein kinase C in pulmonary artery endothelial cells. 1992 J. Biochem. Toxicol. pmid:1404242