MeSH term | MeSH ID | Detail |
---|---|---|
Body Weight | D001835 | 333 associated lipids |
Cell Transformation, Neoplastic | D002471 | 126 associated lipids |
Anemia, Sickle Cell | D000755 | 34 associated lipids |
1,2-Dioleoyl-sn-glycerol is a lipid of Glycerolipids (GL) class. 1,2-dioleoyl-sn-glycerol is associated with abnormalities such as SAPOSIN D (disease) and Exanthema. The involved functions are known as Energy Transfer, Increased Sensitivy, Chelating Activity [MoA], protein kinase C activity and Phosphorylation. 1,2-dioleoyl-sn-glycerol often locates in vesicle, Tissue membrane, Membrane, viral nucleocapsid location and Protoplasm. The associated genes with 1,2-Dioleoyl-sn-glycerol are SIGLEC12 gene, Genome, RNF7 gene, FANCL gene and TNFRSF11B gene. The related lipids are Unilamellar Vesicles, diolein, Phosphatidylserines, Fatty Acids and monoolein.
To understand associated biological information of 1,2-Dioleoyl-sn-glycerol, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
1,2-Dioleoyl-sn-glycerol is suspected in SAPOSIN D (disease), Exanthema and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with 1,2-Dioleoyl-sn-glycerol
MeSH term | MeSH ID | Detail |
---|---|---|
Body Weight | D001835 | 333 associated lipids |
Cell Transformation, Neoplastic | D002471 | 126 associated lipids |
Anemia, Sickle Cell | D000755 | 34 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Melnykovych G et al. | Growth inhibition of leukemia cell line CEM-C1 by farnesol: effects of phosphatidylcholine and diacylglycerol. | 1992 | Biochem. Biophys. Res. Commun. | pmid:1632790 |
Sharkey NA and Blumberg PM | Kinetic evidence that 1,2-diolein inhibits phorbol ester binding to protein kinase C via a competitive mechanism. | 1985 | Biochem. Biophys. Res. Commun. | pmid:3936500 |
Takai Y et al. | Unsaturated diacylglycerol as a possible messenger for the activation of calcium-activated, phospholipid-dependent protein kinase system. 1979. | 2012 | Biochem. Biophys. Res. Commun. | pmid:22925676 |
Senisterra G and Epand RM | Dual modulation of protein kinase C activity by sphingosine. | 1992 | Biochem. Biophys. Res. Commun. | pmid:1530622 |
Epand RM and Stafford AR | Counter-regulatory effects of phosphatidic acid on protein kinase C activity in the presence of calcium and diolein. | 1990 | Biochem. Biophys. Res. Commun. | pmid:2393403 |
Elliott MS and Crane DL | Protein kinase C modulation of queuine uptake in cultured human fibroblasts. | 1990 | Biochem. Biophys. Res. Commun. | pmid:2118349 |
Tsukuda M et al. | Properties of protein kinase C subspecies in human platelets. | 1988 | Biochem. Biophys. Res. Commun. | pmid:3140809 |
Friedman Y et al. | Diacylglycerol-activated, calcium/phospholipid-dependent protein kinase (protein kinase C) activity in bovine thyroid. | 1985 | Biochem. Biophys. Res. Commun. | pmid:3161511 |
Velasco G et al. | Protein kinase C from small intestine epithelial cells. | 1986 | Biochem. Biophys. Res. Commun. | pmid:3768005 |
Bradbury NA and Bridges RJ | Endocytosis is regulated by protein kinase A, but not protein kinase C in a secretory epithelial cell line. | 1992 | Biochem. Biophys. Res. Commun. | pmid:1375455 |