1,2-Dioleoyl-sn-glycerol

1,2-Dioleoyl-sn-glycerol is a lipid of Glycerolipids (GL) class. 1,2-dioleoyl-sn-glycerol is associated with abnormalities such as SAPOSIN D (disease) and Exanthema. The involved functions are known as Energy Transfer, Increased Sensitivy, Chelating Activity [MoA], protein kinase C activity and Phosphorylation. 1,2-dioleoyl-sn-glycerol often locates in vesicle, Tissue membrane, Membrane, viral nucleocapsid location and Protoplasm. The associated genes with 1,2-Dioleoyl-sn-glycerol are SIGLEC12 gene, Genome, RNF7 gene, FANCL gene and TNFRSF11B gene. The related lipids are Unilamellar Vesicles, diolein, Phosphatidylserines, Fatty Acids and monoolein.

Cross Reference

Introduction

To understand associated biological information of 1,2-Dioleoyl-sn-glycerol, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with 1,2-Dioleoyl-sn-glycerol?

1,2-Dioleoyl-sn-glycerol is suspected in SAPOSIN D (disease), Exanthema and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with 1,2-Dioleoyl-sn-glycerol

MeSH term MeSH ID Detail
Body Weight D001835 333 associated lipids
Cell Transformation, Neoplastic D002471 126 associated lipids
Anemia, Sickle Cell D000755 34 associated lipids
Total 3

PubChem Associated disorders and diseases

What pathways are associated with 1,2-Dioleoyl-sn-glycerol

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with 1,2-Dioleoyl-sn-glycerol?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with 1,2-Dioleoyl-sn-glycerol?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with 1,2-Dioleoyl-sn-glycerol?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with 1,2-Dioleoyl-sn-glycerol?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with 1,2-Dioleoyl-sn-glycerol?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with 1,2-Dioleoyl-sn-glycerol

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Authors Title Published Journal PubMed Link
Melnykovych G et al. Growth inhibition of leukemia cell line CEM-C1 by farnesol: effects of phosphatidylcholine and diacylglycerol. 1992 Biochem. Biophys. Res. Commun. pmid:1632790
Sharkey NA and Blumberg PM Kinetic evidence that 1,2-diolein inhibits phorbol ester binding to protein kinase C via a competitive mechanism. 1985 Biochem. Biophys. Res. Commun. pmid:3936500
Takai Y et al. Unsaturated diacylglycerol as a possible messenger for the activation of calcium-activated, phospholipid-dependent protein kinase system. 1979. 2012 Biochem. Biophys. Res. Commun. pmid:22925676
Senisterra G and Epand RM Dual modulation of protein kinase C activity by sphingosine. 1992 Biochem. Biophys. Res. Commun. pmid:1530622
Epand RM and Stafford AR Counter-regulatory effects of phosphatidic acid on protein kinase C activity in the presence of calcium and diolein. 1990 Biochem. Biophys. Res. Commun. pmid:2393403
Elliott MS and Crane DL Protein kinase C modulation of queuine uptake in cultured human fibroblasts. 1990 Biochem. Biophys. Res. Commun. pmid:2118349
Tsukuda M et al. Properties of protein kinase C subspecies in human platelets. 1988 Biochem. Biophys. Res. Commun. pmid:3140809
Friedman Y et al. Diacylglycerol-activated, calcium/phospholipid-dependent protein kinase (protein kinase C) activity in bovine thyroid. 1985 Biochem. Biophys. Res. Commun. pmid:3161511
Velasco G et al. Protein kinase C from small intestine epithelial cells. 1986 Biochem. Biophys. Res. Commun. pmid:3768005
Bradbury NA and Bridges RJ Endocytosis is regulated by protein kinase A, but not protein kinase C in a secretory epithelial cell line. 1992 Biochem. Biophys. Res. Commun. pmid:1375455