| MeSH term | MeSH ID | Detail |
|---|---|---|
| Body Weight | D001835 | 333 associated lipids |
| Cell Transformation, Neoplastic | D002471 | 126 associated lipids |
| Anemia, Sickle Cell | D000755 | 34 associated lipids |
Total
3
1,2-Dioleoyl-sn-glycerol
1,2-Dioleoyl-sn-glycerol is a lipid of Glycerolipids (GL) class. 1,2-dioleoyl-sn-glycerol is associated with abnormalities such as SAPOSIN D (disease) and Exanthema. The involved functions are known as Energy Transfer, Increased Sensitivy, Chelating Activity [MoA], protein kinase C activity and Phosphorylation. 1,2-dioleoyl-sn-glycerol often locates in vesicle, Tissue membrane, Membrane, viral nucleocapsid location and Protoplasm. The associated genes with 1,2-Dioleoyl-sn-glycerol are SIGLEC12 gene, Genome, RNF7 gene, FANCL gene and TNFRSF11B gene. The related lipids are Unilamellar Vesicles, diolein, Phosphatidylserines, Fatty Acids and monoolein.
Cross Reference
Introduction
To understand associated biological information of 1,2-Dioleoyl-sn-glycerol, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with 1,2-Dioleoyl-sn-glycerol?
1,2-Dioleoyl-sn-glycerol is suspected in SAPOSIN D (disease), Exanthema and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
Loading... please refresh the page if content is not showing up.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with 1,2-Dioleoyl-sn-glycerol
PubChem Associated disorders and diseases
What pathways are associated with 1,2-Dioleoyl-sn-glycerol
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with 1,2-Dioleoyl-sn-glycerol?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What functions are associated with 1,2-Dioleoyl-sn-glycerol?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with 1,2-Dioleoyl-sn-glycerol?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What genes are associated with 1,2-Dioleoyl-sn-glycerol?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with 1,2-Dioleoyl-sn-glycerol?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with 1,2-Dioleoyl-sn-glycerol
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Mikawa K et al. | Limited proteolysis of protein kinase C subspecies by calpain: stimulation by basic polypeptides. | 1991 May-Jun | Ital. J. Biochem. | pmid:1856078 |
| Accardo A et al. | Diolein Based Nanostructures as Targeted Theranostics. | 2016 | J Biomed Nanotechnol | pmid:27305827 |
| Piyatheerawong W et al. | Direct separation of regio- and enantiomeric isomers of diacylglycerols by a tandem column high-performance liquid chromatography. | 2005 | J Chromatogr A | pmid:15830930 |
| Wang ZF et al. | Microchip electrophoresis of bacteria using lipid-based liquid crystalline nanoparticles. | 2011 | J Chromatogr A | pmid:21968347 |
| Guo W et al. | Characterization of a novel diolein-based LPDII vector for gene delivery. | 2002 | J Control Release | pmid:12220844 |
| Haeffner EW and Wittmann U | Ca2+ and partly GTP gamma S-dependent particulate phospholipase C hydrolyzing phosphatidylinositol 4-phosphate and phosphatidylinositol 4,5-bisphosphate is inhibited by diacyl(acyl-acetyl) glycerols. | 1992 | J Lipid Mediat | pmid:1334719 |
| Li S et al. | Full utilization of a mass spectrometer using on-demand sharing with multiple LC units. | 2012 | J Mass Spectrom | pmid:22899517 |
| Shimizu M et al. | Elimination of glycidyl palmitate in diolein by treatment with activated bleaching earth. | 2012 | J Oleo Sci | pmid:22188803 |
| Totani N et al. | Ferulic acid esters and weight-loss promoting effects in rats. | 2012 | J Oleo Sci | pmid:22687778 |
| Zhang L et al. | Ionic Hydrogen Bonds and Lipid Packing Defects Determine the Binding Orientation and Insertion Depth of RecA on Multicomponent Lipid Bilayers. | 2016 | J Phys Chem B | pmid:27095675 |
| Laszlo JA et al. | Feruloyl dioleoylglycerol antioxidant capacity in phospholipid vesicles. | 2010 | J. Agric. Food Chem. | pmid:20394373 |
| Shearman GC et al. | A 3-D hexagonal inverse micellar lyotropic phase. | 2009 | J. Am. Chem. Soc. | pmid:19146371 |
| Kuroda T et al. | H1 histone stimulates limited proteolysis of protein kinase C subspecies by calpain II. | 1991 | J. Biochem. | pmid:1769964 |
| Tsujita T and Okuda H | Effect of diolein on hydrolysis of phosphatidylcholine by phospholipase C from Clostridium perfringens. | 1992 | J. Biochem. | pmid:1400264 |
| Patel JM et al. | Oxidant and angiotensin II-induced subcellular translocation of protein kinase C in pulmonary artery endothelial cells. | 1992 | J. Biochem. Toxicol. | pmid:1404242 |
| Smith JD | Differential selectivity of cholinephosphotransferase and ethanolaminephosphotransferase of Tetrahymena for diacylglycerol and alkylacylglycerol. | 1985 | J. Biol. Chem. | pmid:2982806 |
| Gómez-Merino FC et al. | AtDGK2, a novel diacylglycerol kinase from Arabidopsis thaliana, phosphorylates 1-stearoyl-2-arachidonoyl-sn-glycerol and 1,2-dioleoyl-sn-glycerol and exhibits cold-inducible gene expression. | 2004 | J. Biol. Chem. | pmid:14665624 |
| Jenkins CM et al. | Identification, cloning, expression, and purification of three novel human calcium-independent phospholipase A2 family members possessing triacylglycerol lipase and acylglycerol transacylase activities. | 2004 | J. Biol. Chem. | pmid:15364929 |
| BAER E and BUCHNEA D | Synthesis of unsaturated alpha, beta-diglycerides. I. D-alpha, beta-diolein and L-alpha, beta-diolein. | 1958 | J. Biol. Chem. | pmid:13502413 |
| Shirai K et al. | Human plasma carboxyl esterase-catalyzed triolein hydrolysis. Existence of promoting factor in serum. | 1985 | J. Biol. Chem. | pmid:3988750 |
| Gómez-Merino FC et al. | Arabidopsis AtDGK7, the smallest member of plant diacylglycerol kinases (DGKs), displays unique biochemical features and saturates at low substrate concentration: the DGK inhibitor R59022 differentially affects AtDGK2 and AtDGK7 activity in vitro and alters plant growth and development. | 2005 | J. Biol. Chem. | pmid:16081412 |
| Hjelmstad RH and Bell RM | sn-1,2-diacylglycerol choline- and ethanolaminephosphotransferases in Saccharomyces cerevisiae. Mixed micellar analysis of the CPT1 and EPT1 gene products. | 1991 | J. Biol. Chem. | pmid:1847919 |
| Florin-Christensen J et al. | Metabolic fate of plasma membrane diacylglycerols in NIH 3T3 fibroblasts. | 1992 | J. Biol. Chem. | pmid:1634522 |
| Kreutter D et al. | Regulation of protein kinase C activity by gangliosides. | 1987 | J. Biol. Chem. | pmid:2433284 |
| Heidenreich KA et al. | Insulin stimulates the activity of a novel protein kinase C, PKC-epsilon, in cultured fetal chick neurons. | 1990 | J. Biol. Chem. | pmid:2203768 |
| el Touny S et al. | Regulation of platelet protein kinase C by oleic acid. Kinetic analysis of allosteric regulation and effects on autophosphorylation, phorbol ester binding, and susceptibility to inhibition. | 1990 | J. Biol. Chem. | pmid:2118907 |
| Lee TC et al. | Regulation of the synthesis of platelet-activating factor and its inactive storage precursor (1-alkyl-2-acyl-sn-glycero-3-phosphocholine) from 1-alkyl-2-acetyl-sn-glycerol by rabbit platelets. | 1990 | J. Biol. Chem. | pmid:2160964 |
| Smallwood JI et al. | Regulation of erythrocyte Ca2+ pump activity by protein kinase C. | 1988 | J. Biol. Chem. | pmid:2963001 |
| Giugni TD et al. | Activation of a cytosolic serine protein kinase by epidermal growth factor. | 1988 | J. Biol. Chem. | pmid:2974035 |
| Kolesnick RN and Clegg S | 1,2-Diacylglycerols, but not phorbol esters, activate a potential inhibitory pathway for protein kinase C in GH3 pituitary cells. Evidence for involvement of a sphingomyelinase. | 1988 | J. Biol. Chem. | pmid:2834381 |
| Beg ZH et al. | Phosphorylation of hepatic 3-hydroxy-3-methylglutaryl coenzyme A reductase and modulation of its enzymic activity by calcium-activated and phospholipid-dependent protein kinase. | 1985 | J. Biol. Chem. | pmid:3155737 |
| Oishi K et al. | Regulation of protein kinase C by lysophospholipids. Potential role in signal transduction. | 1988 | J. Biol. Chem. | pmid:3360811 |
| Summers TA and Creutz CE | Phosphorylation of a chromaffin granule-binding protein by protein kinase C. | 1985 | J. Biol. Chem. | pmid:3156130 |
| Huang KP et al. | Biochemical characterization of rat brain protein kinase C isozymes. | 1988 | J. Biol. Chem. | pmid:3170568 |
| Liles WC et al. | Activation of protein kinase C induces rapid internalization and subsequent degradation of muscarinic acetylcholine receptors in neuroblastoma cells. | 1986 | J. Biol. Chem. | pmid:3082882 |
| Gonzatti-Haces MI and Traugh JA | Ca2+-independent activation of protease-activated kinase II by phospholipids/diolein and comparison with the Ca2+/phospholipid-dependent protein kinase. | 1986 | J. Biol. Chem. | pmid:3771573 |
| Huang KP et al. | Autophosphorylation of rat brain Ca2+-activated and phospholipid-dependent protein kinase. | 1986 | J. Biol. Chem. | pmid:3462187 |
| Hannun YA et al. | Sphingosine inhibition of protein kinase C activity and of phorbol dibutyrate binding in vitro and in human platelets. | 1986 | J. Biol. Chem. | pmid:3462188 |
| Gopalakrishna R et al. | Factors influencing chelator-stable, detergent-extractable, phorbol diester-induced membrane association of protein kinase C. Differences between Ca2+-induced and phorbol ester-stabilized membrane bindings of protein kinase C. | 1986 | J. Biol. Chem. | pmid:3465725 |
| Ballester R et al. | Phorbol ester- and protein kinase C-mediated phosphorylation of the cellular Kirsten ras gene product. | 1987 | J. Biol. Chem. | pmid:3546293 |
| Hannun YA and Bell RM | Aminoacridines, potent inhibitors of protein kinase C. | 1988 | J. Biol. Chem. | pmid:3258596 |
| Lynch CJ et al. | The hormone-sensitive hepatic Na+-pump. Evidence for regulation by diacylglycerol and tumor promoters. | 1986 | J. Biol. Chem. | pmid:3021743 |
| Maizels ET et al. | Estrogen modulates Ca(2+)-independent lipid-stimulated kinase in the rabbit corpus luteum of pseudopregnancy. Identification of luteal estrogen-modulated lipid-stimulated kinase as protein kinase C delta. | 1992 | J. Biol. Chem. | pmid:1324921 |
| Coolican SA and Hathaway DR | Effect of L-alpha-phosphatidylinositol on a vascular smooth muscle Ca2+-dependent protease. Reduction of the Ca2+ requirement for autolysis. | 1984 | J. Biol. Chem. | pmid:6090440 |
| Nishikawa M et al. | Protein kinase C modulates in vitro phosphorylation of the smooth muscle heavy meromyosin by myosin light chain kinase. | 1984 | J. Biol. Chem. | pmid:6235218 |
| Lee H et al. | Signal transduction through extracellular signal-regulated kinase-like pp57 blocked in differentiated cells having low protein kinase C beta activity. | 1993 | J. Biol. Chem. | pmid:8383133 |
| Lee H et al. | Signal transduction through extracellular signal-regulated kinase-like pp57 blocked in differentiated colon carcinoma cells having low levels of c-src kinase. | 1993 | J. Biol. Chem. | pmid:7681838 |
| Slater SJ et al. | Protein kinase Calpha contains two activator binding sites that bind phorbol esters and diacylglycerols with opposite affinities. | 1996 | J. Biol. Chem. | pmid:8617724 |
| Mosior M and Newton AC | Mechanism of interaction of protein kinase C with phorbol esters. Reversibility and nature of membrane association. | 1995 | J. Biol. Chem. | pmid:7592722 |
| Antonny B et al. | Activation of ADP-ribosylation factor 1 GTPase-activating protein by phosphatidylcholine-derived diacylglycerols. | 1997 | J. Biol. Chem. | pmid:9388229 |