5,8,11-eicosatrienoic acid

5,8,11-eicosatrienoic acid is a lipid of Fatty Acyls (FA) class. 5,8,11-eicosatrienoic acid is associated with abnormalities such as Pulmonary Eosinophilia. The involved functions are known as antagonists, actin polymerization, release of sequestered calcium ion into cytoplasm, Neutrophil migration, function and Chemotaxis. 5,8,11-eicosatrienoic acid often locates in Cytoplasmic matrix and Back. The associated genes with 5,8,11-eicosatrienoic acid are Homologous Gene, IMPACT gene and ALOX12 gene. The related lipids are Fatty Acids and Eicosatrienoic Acid.

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Introduction

To understand associated biological information of 5,8,11-eicosatrienoic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with 5,8,11-eicosatrienoic acid?

5,8,11-eicosatrienoic acid is suspected in Pulmonary Eosinophilia and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with 5,8,11-eicosatrienoic acid

MeSH term MeSH ID Detail
Inflammatory Bowel Diseases D015212 9 associated lipids
Cystic Fibrosis D003550 65 associated lipids
Leukemia, Experimental D007942 42 associated lipids
Atherosclerosis D050197 85 associated lipids
Total 4

PubChem Associated disorders and diseases

What pathways are associated with 5,8,11-eicosatrienoic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with 5,8,11-eicosatrienoic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with 5,8,11-eicosatrienoic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with 5,8,11-eicosatrienoic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with 5,8,11-eicosatrienoic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with 5,8,11-eicosatrienoic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with 5,8,11-eicosatrienoic acid

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Authors Title Published Journal PubMed Link
Paassilta M et al. Food allergy in small children carries a risk of essential fatty acid deficiency, as detected by elevated serum mead acid proportion of total fatty acids. 2014 Lipids Health Dis pmid:25440954
Ichi I et al. Identification of genes and pathways involved in the synthesis of Mead acid (20:3n-9), an indicator of essential fatty acid deficiency. 2014 Biochim. Biophys. Acta pmid:24184513
Hamazaki T et al. Inhibitory effect of 5,8,11-eicosatrienoic acid on angiogenesis. 2012 Prostaglandins Leukot. Essent. Fatty Acids pmid:22521862
Astarita G et al. Elevated stearoyl-CoA desaturase in brains of patients with Alzheimer's disease. 2011 PLoS ONE pmid:22046234
van Goor SA et al. Mildly abnormal general movement quality in infants is associated with higher Mead acid and lower arachidonic acid and shows a U-shaped relation with the DHA/AA ratio. 2010 Prostaglandins Leukot. Essent. Fatty Acids pmid:20022733
Karaman IuK et al. [The role of modification of fatty acid composition of erythrocyte lipids in pathogenesis of arterial hypertension]. 2010 Kardiologiia pmid:20659041
Hamazaki T et al. The depressive effects of 5,8,11-eicosatrienoic Acid (20:3n-9) on osteoblasts. 2009 Lipids pmid:18941818
Coste TC et al. Influence of pancreatic status and sex on polyunsaturated fatty acid profiles in cystic fibrosis. 2008 Clin. Chem. pmid:18089657
Patel P et al. Structural requirements for activation of the 5-oxo-6E,8Z, 11Z,14Z-eicosatetraenoic acid (5-oxo-ETE) receptor: identification of a mead acid metabolite with potent agonist activity. 2008 J. Pharmacol. Exp. Ther. pmid:18292294
Strijbosch RA et al. Fish oil prevents essential fatty acid deficiency and enhances growth: clinical and biochemical implications. 2008 Metab. Clin. Exp. pmid:18442636