MeSH term | MeSH ID | Detail |
---|---|---|
Inflammatory Bowel Diseases | D015212 | 9 associated lipids |
Leukemia, Experimental | D007942 | 42 associated lipids |
Cystic Fibrosis | D003550 | 65 associated lipids |
Atherosclerosis | D050197 | 85 associated lipids |
5,8,11-eicosatrienoic acid is a lipid of Fatty Acyls (FA) class. 5,8,11-eicosatrienoic acid is associated with abnormalities such as Pulmonary Eosinophilia. The involved functions are known as antagonists, actin polymerization, release of sequestered calcium ion into cytoplasm, Neutrophil migration, function and Chemotaxis. 5,8,11-eicosatrienoic acid often locates in Cytoplasmic matrix and Back. The associated genes with 5,8,11-eicosatrienoic acid are Homologous Gene, IMPACT gene and ALOX12 gene. The related lipids are Fatty Acids and Eicosatrienoic Acid.
To understand associated biological information of 5,8,11-eicosatrienoic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
5,8,11-eicosatrienoic acid is suspected in Pulmonary Eosinophilia and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with 5,8,11-eicosatrienoic acid
MeSH term | MeSH ID | Detail |
---|---|---|
Inflammatory Bowel Diseases | D015212 | 9 associated lipids |
Leukemia, Experimental | D007942 | 42 associated lipids |
Cystic Fibrosis | D003550 | 65 associated lipids |
Atherosclerosis | D050197 | 85 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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MEAD JF and SLATON WH | Metabolism of essential fatty acids. III. Isolation of 5,8,11-eicosatrienoic acid from fat-deficient rats. | 1956 | J. Biol. Chem. | pmid:13319291 |
Jakschik BA et al. | Products derived from 5,8,11-eicosatrienoic acid by the 5-lipoxygenase-leukotriene pathway. | 1983 | J. Biol. Chem. | pmid:6313677 |
Oliw EH et al. | Oxygenation of 5,8,11-eicosatrienoic acid by prostaglandin H synthase-2 of ovine placental cotyledons: isolation of 13-hydroxy-5,8,11-eicosatrienoic and 11-hydroxy-5,8,12-eicosatrienoic acids. | 1997 | J. Chromatogr. B Biomed. Sci. Appl. | pmid:9106061 |
Neufeld EJ et al. | High affinity esterification of eicosanoid precursor fatty acids by platelets. | 1983 | J. Clin. Invest. | pmid:6308046 |
James MJ et al. | Effect of dietary supplementation with n-9 eicosatrienoic acid on leukotriene B4 synthesis in rats: a novel approach to inhibition of eicosanoid synthesis. | 1993 | J. Exp. Med. | pmid:8245797 |
Nguyen TT et al. | New model of a scaling dermatosis: induction of hyperproliferation in hairless mice with eicosa-5,8,11-trienoic acid. | 1981 | J. Invest. Dermatol. | pmid:7229430 |
Cleland LG et al. | Dietary (n-9) eicosatrienoic acid from a cultured fungus inhibits leukotriene B4 synthesis in rats and the effect is modified by dietary linoleic acid. | 1996 | J. Nutr. | pmid:8648425 |
Chu SH and Hegsted DM | Assessment of the essential fatty acid requirement in gerbils by polyunsaturated fatty acid ratio. | 1981 | J. Nutr. | pmid:6792330 |
Patel P et al. | Structural requirements for activation of the 5-oxo-6E,8Z, 11Z,14Z-eicosatetraenoic acid (5-oxo-ETE) receptor: identification of a mead acid metabolite with potent agonist activity. | 2008 | J. Pharmacol. Exp. Ther. | pmid:18292294 |
Nubé M et al. | Energy intake and the appearance of 5,8,11-eicosatrienoic acid in serum lipids during parenteral nutrition without fat. | 1982 Mar-Apr | JPEN J Parenter Enteral Nutr | pmid:6808172 |