MeSH term | MeSH ID | Detail |
---|---|---|
Inflammatory Bowel Diseases | D015212 | 9 associated lipids |
Leukemia, Experimental | D007942 | 42 associated lipids |
Cystic Fibrosis | D003550 | 65 associated lipids |
Atherosclerosis | D050197 | 85 associated lipids |
5,8,11-eicosatrienoic acid is a lipid of Fatty Acyls (FA) class. 5,8,11-eicosatrienoic acid is associated with abnormalities such as Pulmonary Eosinophilia. The involved functions are known as antagonists, actin polymerization, release of sequestered calcium ion into cytoplasm, Neutrophil migration, function and Chemotaxis. 5,8,11-eicosatrienoic acid often locates in Cytoplasmic matrix and Back. The associated genes with 5,8,11-eicosatrienoic acid are Homologous Gene, IMPACT gene and ALOX12 gene. The related lipids are Fatty Acids and Eicosatrienoic Acid.
To understand associated biological information of 5,8,11-eicosatrienoic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
5,8,11-eicosatrienoic acid is suspected in Pulmonary Eosinophilia and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with 5,8,11-eicosatrienoic acid
MeSH term | MeSH ID | Detail |
---|---|---|
Inflammatory Bowel Diseases | D015212 | 9 associated lipids |
Leukemia, Experimental | D007942 | 42 associated lipids |
Cystic Fibrosis | D003550 | 65 associated lipids |
Atherosclerosis | D050197 | 85 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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pmid: | ||||
Kanda H et al. | Inhibitors of arachidonic acid metabolism have variable effects on calcium signaling pathways. | 2001 | Am. J. Hypertens. | pmid:11281236 |
Sakuradani E et al. | Production of 5,8,11-eicosatrienoic acid by a delta5 and delta6 desaturation activity-enhanced mutant derived from a delta12 desaturation activity-defective mutant of Mortierella alpina 1S-4. | 2002 | Appl. Microbiol. Biotechnol. | pmid:12436308 |
Fokkema MR et al. | Assessment of essential fatty acid and omega3-fatty acid status by measurement of erythrocyte 20:3omega9 (Mead acid), 22:5omega6/20:4omega6 and 22:5omega6/22:6omega3. | 2002 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:12445496 |
Yoshida H et al. | Beneficial effects of n-9 eicosatrienoic acid on experimental bowel lesions. | 2003 | Surg. Today | pmid:12884098 |
MEAD JF and SLATON WH | Metabolism of essential fatty acids. III. Isolation of 5,8,11-eicosatrienoic acid from fat-deficient rats. | 1956 | J. Biol. Chem. | pmid:13319291 |
Ghebremeskel K and Leighfield M | Infant brain lipids and diet. | 1992 | Lancet | pmid:1357473 |
FULCO AJ and MEAD JF | Metabolism of essential fatty acids. VIII. Origin of 5,8,11-eicosatrienoic acid in the fat-deficient rat. | 1959 | J. Biol. Chem. | pmid:13654388 |
Heyd VL and Eynard AR | Effects of eicosatrienoic acid (20:3 n-9, Mead's acid) on some promalignant-related properties of three human cancer cell lines. | 2003 | Prostaglandins Other Lipid Mediat. | pmid:14518560 |
Nakano N et al. | Effects of arachidonic acid analogs on FcepsilonRI-mediated activation of mast cells. | 2005 | Biochim. Biophys. Acta | pmid:16403671 |