5,8,11-eicosatrienoic acid

5,8,11-eicosatrienoic acid is a lipid of Fatty Acyls (FA) class. 5,8,11-eicosatrienoic acid is associated with abnormalities such as Pulmonary Eosinophilia. The involved functions are known as antagonists, actin polymerization, release of sequestered calcium ion into cytoplasm, Neutrophil migration, function and Chemotaxis. 5,8,11-eicosatrienoic acid often locates in Cytoplasmic matrix and Back. The associated genes with 5,8,11-eicosatrienoic acid are Homologous Gene, IMPACT gene and ALOX12 gene. The related lipids are Fatty Acids and Eicosatrienoic Acid.

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Introduction

To understand associated biological information of 5,8,11-eicosatrienoic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with 5,8,11-eicosatrienoic acid?

5,8,11-eicosatrienoic acid is suspected in Pulmonary Eosinophilia and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with 5,8,11-eicosatrienoic acid

MeSH term MeSH ID Detail
Inflammatory Bowel Diseases D015212 9 associated lipids
Cystic Fibrosis D003550 65 associated lipids
Leukemia, Experimental D007942 42 associated lipids
Atherosclerosis D050197 85 associated lipids
Total 4

PubChem Associated disorders and diseases

What pathways are associated with 5,8,11-eicosatrienoic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with 5,8,11-eicosatrienoic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with 5,8,11-eicosatrienoic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with 5,8,11-eicosatrienoic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with 5,8,11-eicosatrienoic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with 5,8,11-eicosatrienoic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with 5,8,11-eicosatrienoic acid

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Authors Title Published Journal PubMed Link
pmid:
Kanda H et al. Inhibitors of arachidonic acid metabolism have variable effects on calcium signaling pathways. 2001 Am. J. Hypertens. pmid:11281236
Sakuradani E et al. Production of 5,8,11-eicosatrienoic acid by a delta5 and delta6 desaturation activity-enhanced mutant derived from a delta12 desaturation activity-defective mutant of Mortierella alpina 1S-4. 2002 Appl. Microbiol. Biotechnol. pmid:12436308
Fokkema MR et al. Assessment of essential fatty acid and omega3-fatty acid status by measurement of erythrocyte 20:3omega9 (Mead acid), 22:5omega6/20:4omega6 and 22:5omega6/22:6omega3. 2002 Prostaglandins Leukot. Essent. Fatty Acids pmid:12445496
Yoshida H et al. Beneficial effects of n-9 eicosatrienoic acid on experimental bowel lesions. 2003 Surg. Today pmid:12884098
MEAD JF and SLATON WH Metabolism of essential fatty acids. III. Isolation of 5,8,11-eicosatrienoic acid from fat-deficient rats. 1956 J. Biol. Chem. pmid:13319291
Ghebremeskel K and Leighfield M Infant brain lipids and diet. 1992 Lancet pmid:1357473
FULCO AJ and MEAD JF Metabolism of essential fatty acids. VIII. Origin of 5,8,11-eicosatrienoic acid in the fat-deficient rat. 1959 J. Biol. Chem. pmid:13654388
Heyd VL and Eynard AR Effects of eicosatrienoic acid (20:3 n-9, Mead's acid) on some promalignant-related properties of three human cancer cell lines. 2003 Prostaglandins Other Lipid Mediat. pmid:14518560
Nakano N et al. Effects of arachidonic acid analogs on FcepsilonRI-mediated activation of mast cells. 2005 Biochim. Biophys. Acta pmid:16403671