5,8,11-eicosatrienoic acid

5,8,11-eicosatrienoic acid is a lipid of Fatty Acyls (FA) class. 5,8,11-eicosatrienoic acid is associated with abnormalities such as Pulmonary Eosinophilia. The involved functions are known as antagonists, actin polymerization, release of sequestered calcium ion into cytoplasm, Neutrophil migration, function and Chemotaxis. 5,8,11-eicosatrienoic acid often locates in Cytoplasmic matrix and Back. The associated genes with 5,8,11-eicosatrienoic acid are Homologous Gene, IMPACT gene and ALOX12 gene. The related lipids are Fatty Acids and Eicosatrienoic Acid.

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Introduction

To understand associated biological information of 5,8,11-eicosatrienoic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with 5,8,11-eicosatrienoic acid?

5,8,11-eicosatrienoic acid is suspected in Pulmonary Eosinophilia and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with 5,8,11-eicosatrienoic acid

MeSH term MeSH ID Detail
Inflammatory Bowel Diseases D015212 9 associated lipids
Cystic Fibrosis D003550 65 associated lipids
Leukemia, Experimental D007942 42 associated lipids
Atherosclerosis D050197 85 associated lipids
Total 4

PubChem Associated disorders and diseases

What pathways are associated with 5,8,11-eicosatrienoic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with 5,8,11-eicosatrienoic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with 5,8,11-eicosatrienoic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with 5,8,11-eicosatrienoic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with 5,8,11-eicosatrienoic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with 5,8,11-eicosatrienoic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with 5,8,11-eicosatrienoic acid

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Authors Title Published Journal PubMed Link
pmid:29353041
pmid:25669698
pmid:25109488
pmid:26187936
pmid:
MEAD JF and SLATON WH Metabolism of essential fatty acids. III. Isolation of 5,8,11-eicosatrienoic acid from fat-deficient rats. 1956 J. Biol. Chem. pmid:13319291
FULCO AJ and MEAD JF Metabolism of essential fatty acids. VIII. Origin of 5,8,11-eicosatrienoic acid in the fat-deficient rat. 1959 J. Biol. Chem. pmid:13654388
Lundberg WO The significance of cis, cis, cis 5,8,11 eicosatrienoic acid in essential fatty acid deficiency. 1980 Nutr. Rev. pmid:7422146
Orning L et al. Formation of leukotrienes E3, E4 and E5 in rat basophilic leukemia cells. 1981 Eur. J. Biochem. pmid:6273168
Hammarström S Conversion of 5,8,11-eicosatrienoic acid to leukotrienes C3 and D3. 1981 J. Biol. Chem. pmid:6780563