MeSH term | MeSH ID | Detail |
---|---|---|
Inflammatory Bowel Diseases | D015212 | 9 associated lipids |
Cystic Fibrosis | D003550 | 65 associated lipids |
Leukemia, Experimental | D007942 | 42 associated lipids |
Atherosclerosis | D050197 | 85 associated lipids |
5,8,11-eicosatrienoic acid is a lipid of Fatty Acyls (FA) class. 5,8,11-eicosatrienoic acid is associated with abnormalities such as Pulmonary Eosinophilia. The involved functions are known as antagonists, actin polymerization, release of sequestered calcium ion into cytoplasm, Neutrophil migration, function and Chemotaxis. 5,8,11-eicosatrienoic acid often locates in Cytoplasmic matrix and Back. The associated genes with 5,8,11-eicosatrienoic acid are Homologous Gene, IMPACT gene and ALOX12 gene. The related lipids are Fatty Acids and Eicosatrienoic Acid.
To understand associated biological information of 5,8,11-eicosatrienoic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
5,8,11-eicosatrienoic acid is suspected in Pulmonary Eosinophilia and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
---|
We collected disease MeSH terms mapped to the references associated with 5,8,11-eicosatrienoic acid
MeSH term | MeSH ID | Detail |
---|---|---|
Inflammatory Bowel Diseases | D015212 | 9 associated lipids |
Cystic Fibrosis | D003550 | 65 associated lipids |
Leukemia, Experimental | D007942 | 42 associated lipids |
Atherosclerosis | D050197 | 85 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
---|
Function | Cross reference | Weighted score | Related literatures |
---|
Lipid concept | Cross reference | Weighted score | Related literatures |
---|
Gene | Cross reference | Weighted score | Related literatures |
---|
There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
---|---|---|---|---|
Weiner TW and Sprecher H | Arachidonic acid, 5,8,11-eicosatrienoic acid and 5,8,11,14, 17-eicosapentaenoic acid. Dietary manipulation of the levels of these acids in rat liver and platelet phospholipids and their incorporation into human platelet lipids. | 1984 | Biochim. Biophys. Acta | pmid:6320899 |
Jakschik BA et al. | Products derived from 5,8,11-eicosatrienoic acid by the 5-lipoxygenase-leukotriene pathway. | 1983 | J. Biol. Chem. | pmid:6313677 |
Lagarde M et al. | Potentiating effect of 5,8,11-eicosatrienoic acid on human platelet aggregation. | 1983 | Lipids | pmid:6408333 |
Neufeld EJ et al. | High affinity esterification of eicosanoid precursor fatty acids by platelets. | 1983 | J. Clin. Invest. | pmid:6308046 |
Nubé M et al. | Energy intake and the appearance of 5,8,11-eicosatrienoic acid in serum lipids during parenteral nutrition without fat. | 1982 Mar-Apr | JPEN J Parenter Enteral Nutr | pmid:6808172 |
Orning L et al. | Formation of leukotrienes E3, E4 and E5 in rat basophilic leukemia cells. | 1981 | Eur. J. Biochem. | pmid:6273168 |
Chu SH and Hegsted DM | Assessment of the essential fatty acid requirement in gerbils by polyunsaturated fatty acid ratio. | 1981 | J. Nutr. | pmid:6792330 |
Hammarström S | Conversion of 5,8,11-eicosatrienoic acid to leukotrienes C3 and D3. | 1981 | J. Biol. Chem. | pmid:6780563 |
Barr LH et al. | Essential fatty acid deficiency during total parenteral nutrition. | 1981 | Ann. Surg. | pmid:6782957 |
Nguyen TT et al. | New model of a scaling dermatosis: induction of hyperproliferation in hairless mice with eicosa-5,8,11-trienoic acid. | 1981 | J. Invest. Dermatol. | pmid:7229430 |
Kroegel C et al. | Inhibition of the eosinophil chemotactic factor (ECF) release from human PMNs and rat mast cells by arachidonic acid analogs. | 1981 | Cell. Immunol. | pmid:7237570 |
Lundberg WO | The significance of cis, cis, cis 5,8,11 eicosatrienoic acid in essential fatty acid deficiency. | 1980 | Nutr. Rev. | pmid:7422146 |
FULCO AJ and MEAD JF | Metabolism of essential fatty acids. VIII. Origin of 5,8,11-eicosatrienoic acid in the fat-deficient rat. | 1959 | J. Biol. Chem. | pmid:13654388 |
MEAD JF and SLATON WH | Metabolism of essential fatty acids. III. Isolation of 5,8,11-eicosatrienoic acid from fat-deficient rats. | 1956 | J. Biol. Chem. | pmid:13319291 |
pmid: | ||||
pmid:29353041 | ||||
pmid:25669698 | ||||
pmid:25109488 | ||||
pmid:26187936 |