MeSH term | MeSH ID | Detail |
---|---|---|
Inflammatory Bowel Diseases | D015212 | 9 associated lipids |
Cystic Fibrosis | D003550 | 65 associated lipids |
Leukemia, Experimental | D007942 | 42 associated lipids |
Atherosclerosis | D050197 | 85 associated lipids |
5,8,11-eicosatrienoic acid is a lipid of Fatty Acyls (FA) class. 5,8,11-eicosatrienoic acid is associated with abnormalities such as Pulmonary Eosinophilia. The involved functions are known as antagonists, actin polymerization, release of sequestered calcium ion into cytoplasm, Neutrophil migration, function and Chemotaxis. 5,8,11-eicosatrienoic acid often locates in Cytoplasmic matrix and Back. The associated genes with 5,8,11-eicosatrienoic acid are Homologous Gene, IMPACT gene and ALOX12 gene. The related lipids are Fatty Acids and Eicosatrienoic Acid.
To understand associated biological information of 5,8,11-eicosatrienoic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
5,8,11-eicosatrienoic acid is suspected in Pulmonary Eosinophilia and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with 5,8,11-eicosatrienoic acid
MeSH term | MeSH ID | Detail |
---|---|---|
Inflammatory Bowel Diseases | D015212 | 9 associated lipids |
Cystic Fibrosis | D003550 | 65 associated lipids |
Leukemia, Experimental | D007942 | 42 associated lipids |
Atherosclerosis | D050197 | 85 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
---|---|---|---|---|
Lundberg WO | The significance of cis, cis, cis 5,8,11 eicosatrienoic acid in essential fatty acid deficiency. | 1980 | Nutr. Rev. | pmid:7422146 |
Astarita G et al. | Elevated stearoyl-CoA desaturase in brains of patients with Alzheimer's disease. | 2011 | PLoS ONE | pmid:22046234 |
Reich R et al. | Ovarian lipoxygenase activity and its regulation by gonadotropin in the rat. | 1985 | Prostaglandins | pmid:3936117 |
Fokkema MR et al. | Assessment of essential fatty acid and omega3-fatty acid status by measurement of erythrocyte 20:3omega9 (Mead acid), 22:5omega6/20:4omega6 and 22:5omega6/22:6omega3. | 2002 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:12445496 |
van Goor SA et al. | Mildly abnormal general movement quality in infants is associated with higher Mead acid and lower arachidonic acid and shows a U-shaped relation with the DHA/AA ratio. | 2010 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:20022733 |
Hamazaki T et al. | Inhibitory effect of 5,8,11-eicosatrienoic acid on angiogenesis. | 2012 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:22521862 |
Heyd VL and Eynard AR | Effects of eicosatrienoic acid (20:3 n-9, Mead's acid) on some promalignant-related properties of three human cancer cell lines. | 2003 | Prostaglandins Other Lipid Mediat. | pmid:14518560 |
Yoshida H et al. | Beneficial effects of n-9 eicosatrienoic acid on experimental bowel lesions. | 2003 | Surg. Today | pmid:12884098 |
Sicard B and Lagarde M | Incorporation of some eicosanoic acids into endothelial cells--effect on platelet inhibitory activity and prostacyclin production. | 1985 | Thromb. Haemost. | pmid:2992114 |