MeSH term | MeSH ID | Detail |
---|---|---|
Inflammatory Bowel Diseases | D015212 | 9 associated lipids |
Cystic Fibrosis | D003550 | 65 associated lipids |
Leukemia, Experimental | D007942 | 42 associated lipids |
Atherosclerosis | D050197 | 85 associated lipids |
5,8,11-eicosatrienoic acid is a lipid of Fatty Acyls (FA) class. 5,8,11-eicosatrienoic acid is associated with abnormalities such as Pulmonary Eosinophilia. The involved functions are known as antagonists, actin polymerization, release of sequestered calcium ion into cytoplasm, Neutrophil migration, function and Chemotaxis. 5,8,11-eicosatrienoic acid often locates in Cytoplasmic matrix and Back. The associated genes with 5,8,11-eicosatrienoic acid are Homologous Gene, IMPACT gene and ALOX12 gene. The related lipids are Fatty Acids and Eicosatrienoic Acid.
To understand associated biological information of 5,8,11-eicosatrienoic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
5,8,11-eicosatrienoic acid is suspected in Pulmonary Eosinophilia and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with 5,8,11-eicosatrienoic acid
MeSH term | MeSH ID | Detail |
---|---|---|
Inflammatory Bowel Diseases | D015212 | 9 associated lipids |
Cystic Fibrosis | D003550 | 65 associated lipids |
Leukemia, Experimental | D007942 | 42 associated lipids |
Atherosclerosis | D050197 | 85 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
---|---|---|---|---|
Lundberg WO | The significance of cis, cis, cis 5,8,11 eicosatrienoic acid in essential fatty acid deficiency. | 1980 | Nutr. Rev. | pmid:7422146 |
Retterstøl K et al. | Studies on the metabolism of [1-14C]5.8.11-eicosatrienoic (Mead) acid in rat hepatocytes. | 1995 | Biochim. Biophys. Acta | pmid:7492619 |
Farquharson J et al. | Effect of diet on the fatty acid composition of the major phospholipids of infant cerebral cortex. | 1995 | Arch. Dis. Child. | pmid:7741563 |
James MJ et al. | Effect of dietary supplementation with n-9 eicosatrienoic acid on leukotriene B4 synthesis in rats: a novel approach to inhibition of eicosanoid synthesis. | 1993 | J. Exp. Med. | pmid:8245797 |
Oliw EH et al. | Oxygenation of 5,8,11-eicosatrienoic acid by prostaglandin endoperoxide synthase and by cytochrome P450 monooxygenase: structure and mechanism of formation of major metabolites. | 1993 | Arch. Biochem. Biophys. | pmid:8373167 |
Cleland LG et al. | Dietary (n-9) eicosatrienoic acid from a cultured fungus inhibits leukotriene B4 synthesis in rats and the effect is modified by dietary linoleic acid. | 1996 | J. Nutr. | pmid:8648425 |
Cleland LG et al. | Effect of dietary n-9 eicosatrienoic acid on the fatty acid composition of plasma lipid fractions and tissue phospholipids. | 1996 | Lipids | pmid:8869885 |
Oliw EH et al. | Oxygenation of 5,8,11-eicosatrienoic acid by prostaglandin H synthase-2 of ovine placental cotyledons: isolation of 13-hydroxy-5,8,11-eicosatrienoic and 11-hydroxy-5,8,12-eicosatrienoic acids. | 1997 | J. Chromatogr. B Biomed. Sci. Appl. | pmid:9106061 |
Kuroki F et al. | Serum n3 polyunsaturated fatty acids are depleted in Crohn's disease. | 1997 | Dig. Dis. Sci. | pmid:9201073 |