| MeSH term | MeSH ID | Detail |
|---|---|---|
| Adenocarcinoma | D000230 | 166 associated lipids |
| Lung Diseases | D008171 | 37 associated lipids |
| Lung Neoplasms | D008175 | 171 associated lipids |
| Insulinoma | D007340 | 28 associated lipids |
| Pancreatic Neoplasms | D010190 | 77 associated lipids |
| Inflammation | D007249 | 119 associated lipids |
| Reperfusion Injury | D015427 | 65 associated lipids |
| Liver Neoplasms | D008113 | 8 associated lipids |
| Diabetes Mellitus, Type 1 | D003922 | 56 associated lipids |
| Diabetes Mellitus, Type 2 | D003924 | 87 associated lipids |
bishomo-gamma-linolenic acid
Bishomo-gamma-linolenic acid is a lipid of Fatty Acyls (FA) class. Bishomo-gamma-linolenic acid is associated with abnormalities such as Diabetes, Obesity, Hypertensive disease, Cirrhosis and Hepatorenal Syndrome. The involved functions are known as Oxidation, Process, Metabolic Inhibition, epoxide hydrolase activity and Signal Transduction Pathways. Bishomo-gamma-linolenic acid often locates in Protoplasm, Cytoplasmic matrix, soluble, Membrane and Tissue membrane. The associated genes with bishomo-gamma-linolenic acid are P4HTM gene, IMPACT gene, arginine methyl ester, CYP gene and PTGS1 gene. The related lipids are Fatty Acids, 17-octadecynoic acid, Lipopolysaccharides, palmitoleic acid and nervonic acid. The related experimental models are Knock-out and Mouse Model.
Cross Reference
Introduction
To understand associated biological information of bishomo-gamma-linolenic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with bishomo-gamma-linolenic acid?
bishomo-gamma-linolenic acid is suspected in Hypertensive disease, Renal tubular disorder, Diabetes, Renal glomerular disease, Obesity, endothelial dysfunction and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Am. J. Physiol. Heart Circ. Physiol. (3)
- Am. J. Physiol. Renal Physiol. (3)
- J. Lipid Res. (1)
- Others (9)
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with bishomo-gamma-linolenic acid
PubChem Associated disorders and diseases
What pathways are associated with bishomo-gamma-linolenic acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with bishomo-gamma-linolenic acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
- Am. J. Physiol. Heart Circ. Physiol. (4)
- Am. J. Physiol. Renal Physiol. (2)
- Hypertension (1)
- Others (9)
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with bishomo-gamma-linolenic acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with bishomo-gamma-linolenic acid?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with bishomo-gamma-linolenic acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with bishomo-gamma-linolenic acid?
Mouse Model
Mouse Model are used in the study 'Chronic blockade of 20-HETE synthesis reduces polycystic kidney disease in an orthologous rat model of ARPKD.' (Park F et al., 2009) and Mouse Model are used in the study 'Interaction of nitric oxide, 20-HETE, and EETs during functional hyperemia in whisker barrel cortex.' (Liu X et al., 2008).
Knock-out
Knock-out are used in the study 'P-450 metabolites of arachidonic acid in the control of cardiovascular function.' (Roman RJ, 2002).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
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NCBI Entrez Crosslinks
All references with bishomo-gamma-linolenic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Bihzad SM and Yousif MH | 11,12-Epoxyeicosatrienoic acid induces vasodilator response in the rat perfused mesenteric vasculature. | 2017 | Auton Autacoid Pharmacol | pmid:28332266 |
| Yang L et al. | Mechanisms of Vascular Dysfunction in COPD and Effects of a Novel Soluble Epoxide Hydrolase Inhibitor in Smokers. | 2017 | Chest | pmid:27884766 |
| Sporková A et al. | Vasodilatory responses of renal interlobular arteries to epoxyeicosatrienoic acids analog are not enhanced in Ren-2 transgenic hypertensive rats: evidence against a role of direct vascular effects of epoxyeicosatrienoic acids in progression of experimental heart failure. | 2017 | Physiol Res | pmid:27782740 |
| Prasinou P et al. | Fatty acid-based lipidomics and membrane remodeling induced by apoE3 and apoE4 in human neuroblastoma cells. | 2017 | Biochim Biophys Acta Biomembr | pmid:28688796 |
| Yeung J et al. | 12(S)-HETrE, a 12-Lipoxygenase Oxylipin of Dihomo-γ-Linolenic Acid, Inhibits Thrombosis via Gαs Signaling in Platelets. | 2016 | Arterioscler. Thromb. Vasc. Biol. | pmid:27470510 |
| Zhou C et al. | CYP2J2-Derived EETs Attenuated Angiotensin II-Induced Adventitial Remodeling via Reduced Inflammatory Response. | 2016 | Cell. Physiol. Biochem. | pmid:27459385 |
| Luther JM and Brown NJ | Epoxyeicosatrienoic acids and glucose homeostasis in mice and men. | 2016 | Prostaglandins Other Lipid Mediat. | pmid:27448715 |
| JÃchová Å et al. | Epoxyeicosatrienoic acid analog attenuates the development of malignant hypertension, but does not reverse it once established: a study in Cyp1a1-Ren-2 transgenic rats. | 2016 | J. Hypertens. | pmid:27428043 |
| Singh SP et al. | PGC-1 alpha regulates HO-1 expression, mitochondrial dynamics and biogenesis: Role of epoxyeicosatrienoic acid. | 2016 | Prostaglandins Other Lipid Mediat. | pmid:27418542 |
| Wang B et al. | CYP2J2 and its metabolites (epoxyeicosatrienoic acids) attenuate cardiac hypertrophy by activating AMPKα2 and enhancing nuclear translocation of Akt1. | 2016 | Aging Cell | pmid:27416746 |