1-STEAROYL-2-ARACHIDONOYL-SN-GLYCEROL

1-STEAROYL-2-ARACHIDONOYL-SN-GLYCEROL is a lipid of Glycerolipids (GL) class. The involved functions are known as Cell Cycle, Signal Transduction, Nuclear Translocation, enzyme activity and activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway. 1-stearoyl-2-arachidonoyl-sn-glycerol often locates in Nuclear Envelope, membrane fraction, Protoplasm, Membrane and cell process structure. The associated genes with 1-STEAROYL-2-ARACHIDONOYL-SN-GLYCEROL are PDIA3 gene and DGKQ gene. The related lipids are Micelles, Phosphatidylserines, Phosphatidate, Stearates and 1-stearoyl-2-arachidonoylglycerol.

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Introduction

To understand associated biological information of 1-STEAROYL-2-ARACHIDONOYL-SN-GLYCEROL, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with 1-STEAROYL-2-ARACHIDONOYL-SN-GLYCEROL?

There are no associated biomedical information in the current reference collection.

No disease MeSH terms mapped to the current reference collection.

PubChem Associated disorders and diseases

What pathways are associated with 1-STEAROYL-2-ARACHIDONOYL-SN-GLYCEROL

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with 1-STEAROYL-2-ARACHIDONOYL-SN-GLYCEROL?

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What functions are associated with 1-STEAROYL-2-ARACHIDONOYL-SN-GLYCEROL?


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What lipids are associated with 1-STEAROYL-2-ARACHIDONOYL-SN-GLYCEROL?

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What genes are associated with 1-STEAROYL-2-ARACHIDONOYL-SN-GLYCEROL?

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What common seen animal models are associated with 1-STEAROYL-2-ARACHIDONOYL-SN-GLYCEROL?

There are no associated biomedical information in the current reference collection.

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All references with 1-STEAROYL-2-ARACHIDONOYL-SN-GLYCEROL

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Authors Title Published Journal PubMed Link
Shonesy BC et al. The initiation of synaptic 2-AG mobilization requires both an increased supply of diacylglycerol precursor and increased postsynaptic calcium. 2015 Neuropharmacology pmid:25484252
van der Wel T et al. A natural substrate-based fluorescence assay for inhibitor screening on diacylglycerol lipase α. 2015 J. Lipid Res. pmid:25684760
Carrillo C et al. Diacylglycerol-containing oleic acid induces increases in [Ca(2+)](i) via TRPC3/6 channels in human T-cells. 2012 Biochim. Biophys. Acta pmid:22306362
Ruiz M et al. A cardiac-specific robotized cellular assay identified families of human ligands as inducers of PGC-1α expression and mitochondrial biogenesis. 2012 PLoS ONE pmid:23056435
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Aires V et al. Activation of TRPC6 calcium channels by diacylglycerol (DAG)-containing arachidonic acid: a comparative study with DAG-containing docosahexaenoic acid. 2007 Biochimie pmid:17532549
Gómez-Merino FC et al. AtDGK2, a novel diacylglycerol kinase from Arabidopsis thaliana, phosphorylates 1-stearoyl-2-arachidonoyl-sn-glycerol and 1,2-dioleoyl-sn-glycerol and exhibits cold-inducible gene expression. 2004 J. Biol. Chem. pmid:14665624
Lucas P et al. A diacylglycerol-gated cation channel in vomeronasal neuron dendrites is impaired in TRPC2 mutant mice: mechanism of pheromone transduction. 2003 Neuron pmid:14642279
Gamberucci A et al. Diacylglycerol activates the influx of extracellular cations in T-lymphocytes independently of intracellular calcium-store depletion and possibly involving endogenous TRP6 gene products. 2002 Biochem. J. pmid:11988098
Deacon EM et al. Generation of diacylglycerol molecular species through the cell cycle: a role for 1-stearoyl, 2-arachidonyl glycerol in the activation of nuclear protein kinase C-betaII at G2/M. 2002 J. Cell. Sci. pmid:11870217
Tesfai Y et al. A diacylglycerol-activated Ca2+ channel in PC12 cells (an adrenal chromaffin cell line) correlates with expression of the TRP-6 (transient receptor potential) protein. 2001 Biochem. J. pmid:11535132
Fatholahi M et al. Relationship between total and free cellular Mg(2+) during metabolic stimulation of rat cardiac myocytes and perfused hearts. 2000 Arch. Biochem. Biophys. pmid:10666323
Hindenes JO et al. Physical properties of the transmembrane signal molecule, sn-1-stearoyl 2-arachidonoylglycerol. Acyl chain segregation and its biochemical implications. 2000 J. Biol. Chem. pmid:10702245
Hofmann T et al. Direct activation of human TRPC6 and TRPC3 channels by diacylglycerol. 1999 Nature pmid:9930701
Hodgkin MN et al. Purification and characterization of sn-1-stearoyl-2-arachidonoylglycerol kinase from pig testes. 1997 Biochem. J. pmid:9065773
Hubbard WC et al. Quantitation of 1-stearoyl-2-arachidonoyl-sn-3-glycerol in human basophils via gas chromatography-negative ion chemical ionization mass spectrometry. 1996 Anal. Biochem. pmid:8660510