| MeSH term | MeSH ID | Detail |
|---|---|---|
| Glaucoma, Open-Angle | D005902 | 3 associated lipids |
| Leukoencephalopathies | D056784 | 3 associated lipids |
Total
2
Adrenic Acid
Adrenic acid is a lipid of Fatty Acyls (FA) class. Adrenic acid is associated with abnormalities such as DERMATITIS HERPETIFORMIS, FAMILIAL. The involved functions are known as Oxidation, peroxidation, Disease Progression, Regulation and Cytochrome P450 Inhibitors [MoA]. Adrenic acid often locates in White matter, Neuraxis, Myelin, Membrane and Endothelium. The associated genes with Adrenic Acid are PREP gene, iberiotoxin, BGN gene and ALOX12 gene. The related lipids are Fatty Acids, Docosatetraenoic Acid and margaric acid.
Cross Reference
Introduction
To understand associated biological information of Adrenic Acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Adrenic Acid?
Adrenic Acid is suspected in DERMATITIS HERPETIFORMIS, FAMILIAL and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
Loading... please refresh the page if content is not showing up.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Adrenic Acid
PubChem Associated disorders and diseases
What pathways are associated with Adrenic Acid
Lipid pathways are not clear in current pathway databases. We organized associated pathways with Adrenic Acid through full-text articles, including metabolic pathways or pathways of biological mechanisms.
Related references are published most in these journals:
| Pathway name | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Adrenic Acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What functions are associated with Adrenic Acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Adrenic Acid?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What genes are associated with Adrenic Acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Adrenic Acid?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Adrenic Acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Kagan VE et al. | Oxidized arachidonic and adrenic PEs navigate cells to ferroptosis. | 2017 | Nat. Chem. Biol. | pmid:27842066 |
| Chung ML et al. | Hyperoxia elevates adrenic acid peroxidation in marine fish and is associated with reproductive pheromone mediators. | 2015 | Mar Drugs | pmid:25874920 |
| Vaz JS et al. | Omega-6 fatty acids and greater likelihood of suicide risk and major depression in early pregnancy. | 2014 | J Affect Disord | pmid:23726775 |
| Dayaker G et al. | Total synthesis of neuroprotectin D1 analogues derived from omega-6 docosapentaenoic acid (DPA) and adrenic acid (AdA) from a common pivotal, late-stage intermediate. | 2014 | J. Org. Chem. | pmid:24571431 |
| Schumacher MC et al. | A comparative study of tissue ω-6 and ω-3 polyunsaturated fatty acids (PUFA) in benign and malignant pathologic stage pT2a radical prostatectomy specimens. | 2013 | Urol. Oncol. | pmid:21414816 |
| Durand T et al. | F(2)-Dihomo-isoprostanes and brain white matter damage in stage 1 Rett syndrome. | 2013 | Biochimie | pmid:23009927 |
| Sumich AL et al. | Fatty acid correlates of temperament in adolescent boys with attention deficit hyperactivity disorder. | 2013 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:23566869 |
| Guijas C et al. | Phospholipid sources for adrenic acid mobilization in RAW 264.7 macrophages. Comparison with arachidonic acid. | 2012 | Biochim. Biophys. Acta | pmid:22824377 |
| De Felice C et al. | F2-dihomo-isoprostanes as potential early biomarkers of lipid oxidative damage in Rett syndrome. | 2011 | J. Lipid Res. | pmid:21917727 |
| Kopf PG et al. | Adrenic acid metabolites as endogenous endothelium-derived and zona glomerulosa-derived hyperpolarizing factors. | 2010 | Hypertension | pmid:20038752 |
| Messamore E et al. | Niacin sensitivity and the arachidonic acid pathway in schizophrenia. | 2010 | Schizophr. Res. | pmid:20417059 |
| Kaewsuwan S et al. | High level production of adrenic acid in Physcomitrella patens using the algae Pavlova sp. Delta(5)-elongase gene. | 2010 | Bioresour. Technol. | pmid:20106658 |
| VanRollins M et al. | F2-dihomo-isoprostanes arise from free radical attack on adrenic acid. | 2008 | J. Lipid Res. | pmid:18250368 |
| de Groot RH et al. | Exploratory study into the relation between plasma phospholipid fatty acid status and cognitive performance. | 2007 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:17317131 |
| Yi XY et al. | Metabolism of adrenic acid to vasodilatory 1alpha,1beta-dihomo-epoxyeicosatrienoic acids by bovine coronary arteries. | 2007 | Am. J. Physiol. Heart Circ. Physiol. | pmid:17209008 |
| Thomas EA and Yao JK | Clozapine specifically alters the arachidonic acid pathway in mice lacking apolipoprotein D. | 2007 | Schizophr. Res. | pmid:17011169 |
| Ren H et al. | Primary open-angle glaucoma patients have reduced levels of blood docosahexaenoic and eicosapentaenoic acids. | 2006 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:16410047 |
| Lengqvist J et al. | Specificity of receptor-ligand interactions and their effect on dimerisation as observed by electrospray mass spectrometry: bile acids form stable adducts to the RXRalpha. | 2005 | J Mass Spectrom | pmid:16258897 |
| Hirasawa A et al. | Free fatty acids regulate gut incretin glucagon-like peptide-1 secretion through GPR120. | 2005 | Nat. Med. | pmid:15619630 |
| Moloney F et al. | Conjugated linoleic acid supplementation, insulin sensitivity, and lipoprotein metabolism in patients with type 2 diabetes mellitus. | 2004 | Am. J. Clin. Nutr. | pmid:15447895 |
| Wijendran V et al. | Significant utilization of dietary arachidonic acid is for brain adrenic acid in baboon neonates. | 2002 | J. Lipid Res. | pmid:11971947 |
| Martinez M and Mougan I | Fatty acid composition of brain glycerophospholipids in peroxisomal disorders. | 1999 | Lipids | pmid:10478932 |
| MartÃnez M and Mougan I | Fatty acid composition of human brain phospholipids during normal development. | 1998 | J. Neurochem. | pmid:9832152 |
| Chanussot B et al. | Adrenic acid delta4 desaturation and fatty acid composition in the liver of marine-oil fed streptozotocin diabetic rats. | 1997 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:9431819 |
| Hinckley T et al. | Long chain polyunsaturated fatty acids and bovine luteal cell function. | 1996 | Biol. Reprod. | pmid:8828853 |
| Mohammed BS et al. | Reevaluation of the pathway for the metabolism of 7,10,13, 16-docosatetraenoic acid to 4,7,10,13,16-docosapentaenoic acid in rat liver. | 1995 | Arch. Biochem. Biophys. | pmid:7872781 |
| Soares MC et al. | Effect of essential fatty acid deficiency on membrane fatty acid content and growth hormone stimulation of rat pituitaries during postnatal development. | 1995 | J. Lipid Res. | pmid:7666016 |
| Baykousheva SP et al. | Arachidonic acid formed by peroxisomal beta-oxidation of 7,10,13,16-docosatetraenoic acid is esterified into 1-acyl-sn-glycero-3-phosphocholine by microsomes. | 1994 | J. Biol. Chem. | pmid:8034586 |
| Mimouni V et al. | Adrenic acid delta 4 desaturation and fatty acid composition in liver microsomes of spontaneously diabetic Wistar BB rats. | 1994 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:8146207 |
| Tardy B et al. | Priming effect of adrenic acid (22:4(n-6)) on tissue factor activity expressed by thrombin-stimulated endothelial cells. | 1992 | Atherosclerosis | pmid:1642692 |
| Orwig KE et al. | Unique metabolites of eicosapentaenoic acid interfere with corpus luteum function in the ewe. | 1992 | Prostaglandins | pmid:1335585 |
| Alessio ML et al. | Effect of an essential fatty acid deficiency on the phospholipid composition in anterior pituitary membranes. | 1992 | Biochem. Biophys. Res. Commun. | pmid:1567386 |
| Rosenthal MD et al. | Retroconversion and delta 4 desaturation of docosatetraenoate (22:4(n-6)) and docosapentaenoate (22:5(n-3)) by human cells in culture. | 1991 | Biochim. Biophys. Acta | pmid:2031936 |
| Christensen E et al. | Adrenoleukodystrophy. The chain shortening of erucic acid (22:1(n-9)) and adrenic acid (22:4(n-6)) is deficient in neonatal adrenoleukodystrophy and normal in X-linked adrenoleukodistrophy skin fibroblasts. | 1989 | Biochim. Biophys. Acta | pmid:2538146 |
| Bordet JC et al. | Hydroperoxides produced by n-6 lipoxygenation of arachidonic and linoleic acids potentiate synthesis of prostacyclin related compounds. | 1988 | Biochim. Biophys. Acta | pmid:3124885 |
| Rosenthal MD and Hill JR | Elongation of arachidonic and eicosapentaenoic acids limits their availability for thrombin-stimulated release from the glycerolipids of vascular endothelial cells. | 1986 | Biochim. Biophys. Acta | pmid:3002485 |
| Sprecher H and Careaga MM | Metabolism of (n-6) and (n-3) polyunsaturated fatty acids by human platelets. | 1986 | Prostaglandins Leukot Med | pmid:2945210 |
| Hagve TA and Christophersen BO | Evidence for peroxisomal retroconversion of adrenic acid (22:4(n-6)) and docosahexaenoic acids (22:6(n-3)) in isolated liver cells. | 1986 | Biochim. Biophys. Acta | pmid:2935195 |
| Ferretti A and Flanagan VP | Mass spectrometric evidence for the conversion of exogenous adrenate to dihomo-prostaglandins by seminal vesicle cyclo-oxygenase. A comparative study of two animal species. | 1986 | J. Chromatogr. | pmid:3104372 |
| Nakagawa Y and Horrocks LA | Different metabolic rates for arachidonoyl molecular species of ethanolamine glycerophospholipids in rat brain. | 1986 | J. Lipid Res. | pmid:3746131 |
| Igarashi Y and Kimura T | Adrenic acid content in rat adrenal mitochondrial phosphatidylethanolamine and its relation to ACTH-mediated stimulation of cholesterol side chain cleavage reaction. | 1986 | J. Biol. Chem. | pmid:3021726 |
| Mann CJ et al. | Docosatetraenoic acid in endothelial cells: formation, retroconversion to arachidonic acid, and effect on prostacyclin production. | 1986 | Arch. Biochem. Biophys. | pmid:3080955 |
| VanRollins M et al. | Metabolism of 7,10,13,16-docosatetraenoic acid to dihomo-thromboxane, 14-hydroxy-7,10,12-nonadecatrienoic acid and hydroxy fatty acids by human platelets. | 1985 | Biochim. Biophys. Acta | pmid:3918572 |
| Campbell WB et al. | Synthesis of dihomoprostaglandins from adrenic acid (7,10,13,16-docosatetraenoic acid) by human endothelial cells. | 1985 | Biochim. Biophys. Acta | pmid:3931686 |
| Sprecher H et al. | Dihomo-prostaglandins and -thromboxane. A prostaglandin family from adrenic acid that may be preferentially synthesized in the kidney. | 1982 | J. Biol. Chem. | pmid:6801054 |
| Gavino VC et al. | Effect of exogenous adrenic acid on the proliferation and lipid metabolism of cells in tissue culture. | 1981 | Prog. Lipid Res. | pmid:7342096 |
| Gavino VC et al. | Effect of polyunsaturated fatty acids and antioxidants on lipid peroxidation in tissue cultures. | 1981 | J. Lipid Res. | pmid:7288284 |
| pmid: | ||||
| pmid:28890136 | ||||
| pmid:28456640 |