7,10,13,16,19-docosapentaenoic acid

7,10,13,16,19-docosapentaenoic acid is a lipid of Fatty Acyls (FA) class.

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There are no associated biomedical information in the current reference collection.

Current reference collection contains 1255 references associated with 7,10,13,16,19-docosapentaenoic acid in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.

Users can download the reference list at the bottom of this page and read the reference manually to find out biomedical information.


Here are additional resources we collected from PubChem and MeSH for 7,10,13,16,19-docosapentaenoic acid

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with 7,10,13,16,19-docosapentaenoic acid

MeSH term MeSH ID Detail
Kidney Failure, Chronic D007676 51 associated lipids
Body Weight D001835 333 associated lipids
Heart Failure D006333 36 associated lipids
Cell Transformation, Neoplastic D002471 126 associated lipids
Carcinoma, Hepatocellular D006528 140 associated lipids
Zellweger Syndrome D015211 39 associated lipids
Atrial Fibrillation D001281 16 associated lipids
Metabolic Syndrome D024821 44 associated lipids
Death, Sudden, Cardiac D016757 12 associated lipids
Chromosome Disorders D025063 4 associated lipids
Total 10

PubChem Biomolecular Interactions and Pathways

NCBI Entrez Crosslinks

All references with 7,10,13,16,19-docosapentaenoic acid

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Authors Title Published Journal PubMed Link
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Maki KC et al. Effects of MAT9001 containing eicosapentaenoic acid and docosapentaenoic acid, compared to eicosapentaenoic acid ethyl esters, on triglycerides, lipoprotein cholesterol, and related variables. J Clin Lipidol pmid:28391875
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Iritani N et al. Identification of shellfish fatty acids and their effects on lipogenic enzymes. 1980 Biochim. Biophys. Acta pmid:6104986
Bazan HE et al. Chain elongation and desaturation of eicosapentaenoate to docosahexaenoate and phospholipid labeling in the rat retina in vivo. 1982 Biochim. Biophys. Acta pmid:6288109
Rosenthal MD and Whitehurst MC Selective utilization of omega 6 and omega 3 polyunsaturated fatty acids by human skin fibroblasts. 1982 J. Cell. Physiol. pmid:6294123
Chanmugam P et al. Fatty acid composition of the testes of zinc-deficient rats: the effect of docosapentaenoic acid supplementation. 1984 J. Nutr. pmid:6491760
Careaga MM and Sprecher H Synthesis of two hydroxy fatty acids from 7,10,13,16,19-docosapentaenoic acid by human platelets. 1984 J. Biol. Chem. pmid:6438096
Fogerty AC et al. Liver fatty acids and the sudden infant death syndrome. 1984 Am. J. Clin. Nutr. pmid:6230001
Milks MM and Sprecher H Metabolism of 4,7,10,13,16-docosapentaenoic acid by human platelet cyclooxygenase and lipoxygenase. 1985 Biochim. Biophys. Acta pmid:3924108
Organisciak DT et al. Rod outer segment lipids in vitamin A-adequate and -deficient rats. 1986 Exp. Eye Res. pmid:2937648
Nielsen JC et al. Rabbit photoreceptor outer segments contain high levels of docosapentaenoic acid. 1986 Invest. Ophthalmol. Vis. Sci. pmid:3943950
Rotstein NP and Aveldaño MI Labeling of lipids of retina subcellular fractions by [1-14C]eicosatetraenoate (20:4(n-6)) docosapentaenoate (22:5(n-3)) and docosahexaenoate (22:6(n-3)). 1987 Biochim. Biophys. Acta pmid:2958089
Rotstein NP and Aveldaño MI Labeling of phosphatidylcholines of retina subcellular fractions by [1-14C]eicosatetraenoate (20:4(n-6)), docosapentaenoate (22:5(n-3)) and docosahexaenoate (22:6(n-3)). 1987 Biochim. Biophys. Acta pmid:2958090
Olsen SF et al. Gestational age in relation to marine n-3 fatty acids in maternal erythrocytes: a study of women in the Faroe Islands and Denmark. 1991 Am. J. Obstet. Gynecol. pmid:1827949
Rosenthal MD et al. Retroconversion and delta 4 desaturation of docosatetraenoate (22:4(n-6)) and docosapentaenoate (22:5(n-3)) by human cells in culture. 1991 Biochim. Biophys. Acta pmid:2031936
Voss A et al. The metabolism of 7,10,13,16,19-docosapentaenoic acid to 4,7,10,13,16,19-docosahexaenoic acid in rat liver is independent of a 4-desaturase. 1991 J. Biol. Chem. pmid:1834642
Lin DS et al. High levels of the (n-6) fatty acid 4,7,10,13,16-docosapentaenoate in the retinas of rabbits are reduced by feeding dietary fish oil from birth to adult life. 1991 J. Nutr. pmid:1941256
Farquharson J et al. Infant cerebral cortex phospholipid fatty-acid composition and diet. 1992 Lancet pmid:1357244
Thomas DW et al. Quantitative determination of hydroxy fatty acids as an indicator of in vivo lipid peroxidation: oxidation products of arachidonic and docosapentaenoic acids in rat liver after exposure to carbon tetrachloride. 1992 Anal. Biochem. pmid:1443605
Parks JS and Thuren TY Decreased binding of apoA-I to phosphatidylcholine monolayers containing 22:6 n-3 in the sn-2 position. 1993 J. Lipid Res. pmid:8509716
Hoffman DR et al. Effects of supplementation with omega 3 long-chain polyunsaturated fatty acids on retinal and cortical development in premature infants. 1993 Am. J. Clin. Nutr. pmid:8475899
Alvarez RA et al. Docosapentaenoic acid is converted to docosahexaenoic acid in the retinas of normal and prcd-affected miniature poodle dogs. 1994 Invest. Ophthalmol. Vis. Sci. pmid:8112987
Sasaki YF et al. Bio-anticlastogenic effects of unsaturated fatty acids included in fish oil--docosahexaenoic acid, docosapentaenoic acid, and eicosapentaenoic acid--in cultured Chinese hamster cells. 1994 Mutat. Res. pmid:7506391
Moore SA et al. Docosahexaenoic acid synthesis in human skin fibroblasts involves peroxisomal retroconversion of tetracosahexaenoic acid. 1995 J. Lipid Res. pmid:8656081
Mohammed BS et al. Reevaluation of the pathway for the metabolism of 7,10,13, 16-docosatetraenoic acid to 4,7,10,13,16-docosapentaenoic acid in rat liver. 1995 Arch. Biochem. Biophys. pmid:7872781
Pawlosky RJ and Salem N Ethanol exposure causes a decrease in docosahexaenoic acid and an increase in docosapentaenoic acid in feline brains and retinas. 1995 Am. J. Clin. Nutr. pmid:7762532
Achard F et al. Interconversions and distinct metabolic fate of eicosapentaenoic, docosapentaenoic and docosahexaenoic acids in bovine aortic endothelial cells. 1995 Biochim. Biophys. Acta pmid:7734441
Farquharson J et al. Effect of diet on the fatty acid composition of the major phospholipids of infant cerebral cortex. 1995 Arch. Dis. Child. pmid:7741563
Leichsenring M et al. Polyunsaturated fatty acids in erythrocyte and plasma lipids of children with severe protein-energy malnutrition. 1995 Acta Paediatr. pmid:7633146
Prisco D et al. Effect of n-3 polyunsaturated fatty acid intake on phospholipid fatty acid composition in plasma and erythrocytes. 1996 Am. J. Clin. Nutr. pmid:8644688
Rotstein NP et al. Active synthesis of C24:5, n-3 fatty acid in retina. 1996 Biochem. J. pmid:8670163
Brossard N et al. Retroconversion and metabolism of [13C]22:6n-3 in humans and rats after intake of a single dose of [13C]22:6n-3-triacylglycerols. 1996 Am. J. Clin. Nutr. pmid:8839503
Infante JP and Huszagh VA On the molecular etiology of decreased arachidonic (20:4n-6), docosapentaenoic (22:5n-6) and docosahexaenoic (22:6n-3) acids in Zellweger syndrome and other peroxisomal disorders. 1997 Mol. Cell. Biochem. pmid:9062899
Campan P et al. Pilot study on n-3 polyunsaturated fatty acids in the treatment of human experimental gingivitis. 1997 J. Clin. Periodontol. pmid:9442428
Mizutani M et al. Omega-3 polyunsaturated fatty acids inhibit migration of human vascular smooth muscle cells in vitro. 1997 Life Sci. pmid:9364203
Mohammed BS et al. Regulation of the biosynthesis of 4,7,10,13,16-docosapentaenoic acid. 1997 Biochem. J. pmid:9291114
Herzberg GR and Skinner C Differential accumulation and release of long-chain n-3 fatty acids from liver, muscle, and adipose tissue triacylglycerols. 1997 Can. J. Physiol. Pharmacol. pmid:9360007
Reece MS et al. Maternal and perinatal long-chain fatty acids: possible roles in preterm birth. 1997 Am. J. Obstet. Gynecol. pmid:9125620
Infante JP and Huszagh VA Analysis of the putative role of 24-carbon polyunsaturated fatty acids in the biosynthesis of docosapentaenoic (22:5n-6) and docosahexaenoic (22:6n-3) acids. 1998 FEBS Lett. pmid:9684854
Ghebremeskel K et al. Maternal diet high in fat reduces docosahexaenoic acid in liver lipids of newborn and sucking rat pups. 1999 Br. J. Nutr. pmid:10615212
Pirich C et al. Effects of fish oil supplementation on platelet survival and ex vivo platelet function in hypercholesterolemic patients. 1999 Thromb. Res. pmid:10588465
Conquer JA et al. Effect of supplementation with dietary seal oil on selected cardiovascular risk factors and hemostatic variables in healthy male subjects. 1999 Thromb. Res. pmid:10588467
Meinelt T et al. Correlation of diets high in n-6 polyunsaturated fatty acids with high growth rate in zebrafish (Danio rerio). 2000 Comp. Med. pmid:10987667
Retterstøl K et al. The pathway from arachidonic to docosapentaenoic acid (20:4n-6 to 22:5n-6) and from eicosapentaenoic to docosahexaenoic acid (20:5n-3 to 22:6n-3) studied in testicular cells from immature rats. 2000 Biochim. Biophys. Acta pmid:10601701
Rissanen T et al. Fish oil-derived fatty acids, docosahexaenoic acid and docosapentaenoic acid, and the risk of acute coronary events: the Kuopio ischaemic heart disease risk factor study. 2000 Circulation pmid:11094031
Assies J et al. Significantly reduced docosahexaenoic and docosapentaenoic acid concentrations in erythrocyte membranes from schizophrenic patients compared with a carefully matched control group. 2001 Biol. Psychiatry pmid:11257236
Helland IB et al. Similar effects on infants of n-3 and n-6 fatty acids supplementation to pregnant and lactating women. 2001 Pediatrics pmid:11694666
Tran TN and Christophersen BO Studies on the transport of acetyl groups from peroxisomes to mitochondria in isolated liver cells oxidizing the polyunsaturated fatty acid 22:4n-6. 2001 Biochim. Biophys. Acta pmid:11731335
Matorras R et al. Longitudinal study of fatty acids in plasma and erythrocyte phospholipids during pregnancy. 2001 J Perinat Med pmid:11565197
Kobayashi M et al. Single measurement of serum phospholipid fatty acid as a biomarker of specific fatty acid intake in middle-aged Japanese men. 2001 Eur J Clin Nutr pmid:11477462
Schneider SM et al. Activity of the leukocyte NADPH oxidase in whole neutrophils and cell-free neutrophil preparations stimulated with long-chain polyunsaturated fatty acids. 2001 Inflammation pmid:11293662
Hammond BG et al. Safety assessment of DHA-rich microalgae from Schizochytrium sp. 2001 Regul. Toxicol. Pharmacol. pmid:11407938
Burdge GC et al. Eicosapentaenoic and docosapentaenoic acids are the principal products of alpha-linolenic acid metabolism in young men*. 2002 Br. J. Nutr. pmid:12323085
Burdge GC and Wootton SA Conversion of alpha-linolenic acid to eicosapentaenoic, docosapentaenoic and docosahexaenoic acids in young women. 2002 Br. J. Nutr. pmid:12323090
Innis SM and Dyer RA Brain astrocyte synthesis of docosahexaenoic acid from n-3 fatty acids is limited at the elongation of docosapentaenoic acid. 2002 J. Lipid Res. pmid:12235185