DHA

Dha is a lipid of Fatty Acyls (FA) class. Dha is associated with abnormalities such as Atherosclerosis, Consumption-archaic term for TB, Chronic disease, Cardiovascular Diseases and Diabetes Mellitus, Non-Insulin-Dependent. The involved functions are known as Inflammation, Oxidation, fatty acid oxidation, Fatty Acid Metabolism and Lipid Metabolism. Dha often locates in Hepatic, Protoplasm, Mucous Membrane, Epithelium and outer membrane. The associated genes with DHA are IMPACT gene, FATE1 gene, GAPDH gene, THOC4 gene and SLC33A1 gene. The related lipids are stearidonic acid, Fatty Acids, Total cholesterol, Lipopolysaccharides and Dietary Fatty Acid. The related experimental models are Mouse Model, Transgenic Model, Animal Disease Models and Arthritis, Experimental.

Cross Reference

Introduction

To understand associated biological information of DHA, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with DHA?

DHA is suspected in Cardiovascular Diseases, Obesity, Ischemia, Hypertensive disease, Coronary Arteriosclerosis, Cerebrovascular accident and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with DHA

MeSH term MeSH ID Detail
Dysbiosis D064806 2 associated lipids
Chronic Pain D059350 5 associated lipids
Peripheral Nerve Injuries D059348 6 associated lipids
Peripheral Arterial Disease D058729 7 associated lipids
Plaque, Atherosclerotic D058226 7 associated lipids
Plaque, Amyloid D058225 19 associated lipids
Acute Kidney Injury D058186 34 associated lipids
Geographic Atrophy D057092 1 associated lipids
Acute Lung Injury D055371 33 associated lipids
Precursor T-Cell Lymphoblastic Leukemia-Lymphoma D054218 5 associated lipids
Acute Coronary Syndrome D054058 11 associated lipids
Hypercalciuria D053565 4 associated lipids
Refsum Disease, Infantile D052919 1 associated lipids
Histiocytoma, Malignant Fibrous D051677 1 associated lipids
Atherosclerosis D050197 85 associated lipids
Dyslipidemias D050171 7 associated lipids
Decapitation D049248 2 associated lipids
Diabetes Complications D048909 4 associated lipids
Premature Birth D047928 6 associated lipids
Malnutrition D044342 6 associated lipids
Metabolic Syndrome D024821 44 associated lipids
Hypoxia-Ischemia, Brain D020925 22 associated lipids
Dyskinesias D020820 3 associated lipids
Spinocerebellar Ataxias D020754 4 associated lipids
Parkinsonian Disorders D020734 20 associated lipids
Multiple Sclerosis, Relapsing-Remitting D020529 7 associated lipids
Stroke D020521 32 associated lipids
Brain Infarction D020520 17 associated lipids
Muscular Dystrophy, Duchenne D020388 11 associated lipids
Intracranial Hemorrhages D020300 2 associated lipids
Neurotoxicity Syndromes D020258 34 associated lipids
Infarction, Middle Cerebral Artery D020244 35 associated lipids
Cerebrovascular Trauma D020214 1 associated lipids
Sleep Apnea, Obstructive D020181 9 associated lipids
Genetic Predisposition to Disease D020022 24 associated lipids
Neurodegenerative Diseases D019636 32 associated lipids
Neuroaxonal Dystrophies D019150 3 associated lipids
Burkholderia Infections D019121 7 associated lipids
Depression, Postpartum D019052 3 associated lipids
Chondrodysplasia Punctata, Rhizomelic D018902 4 associated lipids
Peroxisomal Disorders D018901 5 associated lipids
Carcinoma, Lewis Lung D018827 22 associated lipids
Sepsis D018805 11 associated lipids
Ventricular Dysfunction, Left D018487 33 associated lipids
Pneumonia, Bacterial D018410 16 associated lipids
Trophoblastic Tumor, Placental Site D018245 1 associated lipids
Carcinoma, Embryonal D018236 8 associated lipids
Glucose Intolerance D018149 13 associated lipids
Phenylketonuria, Maternal D017042 1 associated lipids
Keratitis, Herpetic D016849 5 associated lipids
Death, Sudden, Cardiac D016757 12 associated lipids
Diabetes, Gestational D016640 8 associated lipids
Critical Illness D016638 13 associated lipids
Milk Hypersensitivity D016269 4 associated lipids
Mammary Neoplasms, Animal D015674 27 associated lipids
Leukemia, Basophilic, Acute D015471 9 associated lipids
Leukemia, Prolymphocytic D015463 2 associated lipids
Leukemia-Lymphoma, Adult T-Cell D015459 25 associated lipids
Leukemia, Lymphocytic, Chronic, B-Cell D015451 25 associated lipids
Weight Loss D015431 56 associated lipids
Weight Gain D015430 101 associated lipids
Myocardial Reperfusion Injury D015428 20 associated lipids
Reperfusion Injury D015427 65 associated lipids
Dry Eye Syndromes D015352 10 associated lipids
Zellweger Syndrome D015211 39 associated lipids
Colorectal Neoplasms D015179 10 associated lipids
Dementia, Vascular D015140 7 associated lipids
Vitamin E Deficiency D014811 29 associated lipids
Vision Disorders D014786 10 associated lipids
Vibrio Infections D014735 5 associated lipids
Ventricular Fibrillation D014693 16 associated lipids
Vascular Diseases D014652 16 associated lipids
Uveitis D014605 14 associated lipids
Uterine Neoplasms D014594 18 associated lipids
Thymus Neoplasms D013953 15 associated lipids
Thrombosis D013927 49 associated lipids
Stomach Ulcer D013276 75 associated lipids
Spinal Cord Injuries D013119 34 associated lipids
Sleep Wake Disorders D012893 7 associated lipids
Short Bowel Syndrome D012778 3 associated lipids
Shock D012769 11 associated lipids
Seizures D012640 87 associated lipids
Retinoblastoma D012175 12 associated lipids
Retinitis Pigmentosa D012174 6 associated lipids
Retinal Detachment D012163 10 associated lipids
Refsum Disease D012035 19 associated lipids
Pulmonary Valve Stenosis D011666 1 associated lipids
Pulmonary Fibrosis D011658 24 associated lipids
Psoriasis D011565 47 associated lipids
Pseudomonas Infections D011552 25 associated lipids
Proteinuria D011507 30 associated lipids
Prostatic Neoplasms D011471 126 associated lipids
Pregnancy Complications, Hematologic D011250 11 associated lipids
Pregnancy Complications, Cardiovascular D011249 11 associated lipids
Pregnancy Complications D011248 19 associated lipids
Precancerous Conditions D011230 48 associated lipids
Polycystic Ovary Syndrome D011085 14 associated lipids
Pneumonia D011014 10 associated lipids
Peritonitis D010538 38 associated lipids
Peritoneal Neoplasms D010534 16 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with DHA

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with DHA?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with DHA?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with DHA?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with DHA?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with DHA?

Mouse Model

Mouse Model are used in the study 'Homeostatic regulation of photoreceptor cell integrity: significance of the potent mediator neuroprotectin D1 biosynthesized from docosahexaenoic acid: the Proctor Lecture.' (Bazan NG, 2007), Mouse Model are used in the study 'Omega-3 fatty acids EPA and DHA: health benefits throughout life.' (Swanson D et al., 2012), Mouse Model are used in the study 'Docosahexaenoic acid attenuates hepatic inflammation, oxidative stress, and fibrosis without decreasing hepatosteatosis in a Ldlr(-/-) mouse model of western diet-induced nonalcoholic steatohepatitis.' (Depner CM et al., 2013) and Mouse Model are used in the study 'Wax esters from the marine copepod Calanus finmarchicus reduce diet-induced obesity and obesity-related metabolic disorders in mice.' (Höper AC et al., 2014).

Transgenic Model

Transgenic Model are used in the study 'Loss of MAP function leads to hippocampal synapse loss and deficits in the Morris Water Maze with aging.' (Ma QL et al., 2014).

Animal Disease Models

Animal Disease Models are used in the study 'Fish oil increases muscle protein mass and modulates Akt/FOXO, TLR4, and NOD signaling in weanling piglets after lipopolysaccharide challenge.' (Liu Y et al., 2013).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with DHA

Download all related citations
Per page 10 20 50 100 | Total 7336
Authors Title Published Journal PubMed Link
Liu Q et al. Dietary n-6:n-3 ratio and Vitamin E improve motility characteristics in association with membrane properties of boar spermatozoa. 2017 Mar-Apr Asian J. Androl. pmid:26763547
Manni A et al. Stearoyl-CoA desaturase-1, a novel target of omega-3 fatty acids for reducing breast cancer risk in obese postmenopausal women. 2017 Eur J Clin Nutr pmid:28145413
Burak C et al. Effects of the flavonol quercetin and α-linolenic acid on n-3 PUFA status in metabolically healthy men and women: a randomised, double-blinded, placebo-controlled, crossover trial. 2017 Br. J. Nutr. pmid:28366181
Pascoal LB et al. Resolvin RvD2 reduces hypothalamic inflammation and rescues mice from diet-induced obesity. 2017 J Neuroinflammation pmid:28086928
Stylos E et al. Tailoring naringenin conjugates with amplified and triple antiplatelet activity profile: Rational design, synthesis, human plasma stability and in vitro evaluation. 2017 Biochim Biophys Acta Gen Subj pmid:28844979
Maoka T et al. Carotenoids of Red, Brown, and Black Specimens of Plectropomus leopardus, the Coral Trout (Suziara in Japanese). 2017 J Oleo Sci pmid:28515376
Lee Y et al. Analysis of endogenous lipids during intestinal wound healing. 2017 PLoS ONE pmid:28800645
Wang Y et al. Docosahexaenoyl serotonin emerges as most potent inhibitor of IL-17 and CCL-20 released by blood mononuclear cells from a series of N-acyl serotonins identified in human intestinal tissue. 2017 Biochim. Biophys. Acta pmid:28526351
Senftleber NK et al. Marine Oil Supplements for Arthritis Pain: A Systematic Review and Meta-Analysis of Randomized Trials. 2017 Nutrients pmid:28067815
Mottola G et al. Aspirin-triggered resolvin D1 attenuates PDGF-induced vascular smooth muscle cell migration via the cyclic adenosine monophosphate/protein kinase A (cAMP/PKA) pathway. 2017 PLoS ONE pmid:28362840