| MeSH term | MeSH ID | Detail |
|---|---|---|
| Phenylketonuria, Maternal | D017042 | 1 associated lipids |
| Lordosis | D008141 | 1 associated lipids |
| Refsum Disease, Infantile | D052919 | 1 associated lipids |
| Pulmonary Valve Stenosis | D011666 | 1 associated lipids |
| Cerebrovascular Trauma | D020214 | 1 associated lipids |
| Histiocytoma, Malignant Fibrous | D051677 | 1 associated lipids |
| Hydroa Vacciniforme | D006837 | 1 associated lipids |
| Communication Disorders | D003147 | 1 associated lipids |
| Trophoblastic Tumor, Placental Site | D018245 | 1 associated lipids |
| Geographic Atrophy | D057092 | 1 associated lipids |
| Dementia | D003704 | 2 associated lipids |
| Dysbiosis | D064806 | 2 associated lipids |
| Paracoccidioidomycosis | D010229 | 2 associated lipids |
| Intracranial Hemorrhages | D020300 | 2 associated lipids |
| Leukemia, Prolymphocytic | D015463 | 2 associated lipids |
| Decapitation | D049248 | 2 associated lipids |
| Dyskinesias | D020820 | 3 associated lipids |
| Myocarditis | D009205 | 3 associated lipids |
| Neuroaxonal Dystrophies | D019150 | 3 associated lipids |
| Glaucoma, Open-Angle | D005902 | 3 associated lipids |
DHA
Dha is a lipid of Fatty Acyls (FA) class. Dha is associated with abnormalities such as Atherosclerosis, Consumption-archaic term for TB, Chronic disease, Cardiovascular Diseases and Diabetes Mellitus, Non-Insulin-Dependent. The involved functions are known as Inflammation, Oxidation, fatty acid oxidation, Fatty Acid Metabolism and Lipid Metabolism. Dha often locates in Hepatic, Protoplasm, Mucous Membrane, Epithelium and outer membrane. The associated genes with DHA are IMPACT gene, FATE1 gene, GAPDH gene, THOC4 gene and SLC33A1 gene. The related lipids are stearidonic acid, Fatty Acids, Total cholesterol, Lipopolysaccharides and Dietary Fatty Acid. The related experimental models are Mouse Model, Transgenic Model, Animal Disease Models and Arthritis, Experimental.
Cross Reference
Introduction
To understand associated biological information of DHA, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with DHA?
DHA is suspected in Cardiovascular Diseases, Obesity, Ischemia, Hypertensive disease, Coronary Arteriosclerosis, Cerebrovascular accident and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with DHA
PubChem Associated disorders and diseases
What pathways are associated with DHA
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with DHA?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with DHA?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with DHA?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with DHA?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with DHA?
Mouse Model
Mouse Model are used in the study 'Homeostatic regulation of photoreceptor cell integrity: significance of the potent mediator neuroprotectin D1 biosynthesized from docosahexaenoic acid: the Proctor Lecture.' (Bazan NG, 2007), Mouse Model are used in the study 'Omega-3 fatty acids EPA and DHA: health benefits throughout life.' (Swanson D et al., 2012), Mouse Model are used in the study 'Docosahexaenoic acid attenuates hepatic inflammation, oxidative stress, and fibrosis without decreasing hepatosteatosis in a Ldlr(-/-) mouse model of western diet-induced nonalcoholic steatohepatitis.' (Depner CM et al., 2013) and Mouse Model are used in the study 'Wax esters from the marine copepod Calanus finmarchicus reduce diet-induced obesity and obesity-related metabolic disorders in mice.' (Höper AC et al., 2014).
Transgenic Model
Transgenic Model are used in the study 'Loss of MAP function leads to hippocampal synapse loss and deficits in the Morris Water Maze with aging.' (Ma QL et al., 2014).
Animal Disease Models
Animal Disease Models are used in the study 'Fish oil increases muscle protein mass and modulates Akt/FOXO, TLR4, and NOD signaling in weanling piglets after lipopolysaccharide challenge.' (Liu Y et al., 2013).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
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NCBI Entrez Crosslinks
All references with DHA
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Wang N and Anderson RE | Transport of 22:6n-3 in the plasma and uptake into retinal pigment epithelium and retina. | 1993 | Exp. Eye Res. | pmid:8405189 |
| Nakamura N et al. | Intravenous infusion of tridocosahexaenoyl-glycerol emulsion into rabbits. Effects on leukotriene B4/5 production and fatty acid composition of plasma and leukocytes. | 1993 | J. Clin. Invest. | pmid:8397222 |
| Nishio K et al. | Novel water-soluble derivatives of docosahexaenoic acid increase diacylglycerol production mediated by phosphatidylcholine-specific phospholipase C. | 1993 | Proc. Soc. Exp. Biol. Med. | pmid:8389049 |
| Otten W et al. | A high omega 3 fatty acid diet alters fatty acid composition of heart, liver, kidney, adipose tissue and skeletal muscle in swine. | 1993 | Ann. Nutr. Metab. | pmid:8373137 |
| Anderson GJ et al. | Uptake of docosahexaenoic acid by microvessels from developing rat brain. | 1993 | Life Sci. | pmid:8366771 |
| Abu-Zeid YA et al. | No effect of human serum and erythrocytes enriched in n-3 fatty acids by oral intake on Plasmodium falciparum blood stage parasites in vitro. | 1993 | Eur J Clin Nutr | pmid:8365384 |
| Hodge J et al. | Differential utilization of eicosapentaenoic acid and docosahexaenoic acid in human plasma. | 1993 | Lipids | pmid:8355578 |
| Hamazaki T et al. | Effect of intravenous administration of docosahexaenoic acid emulsion on blood glucose and insulin concentrations in diabetic rats. | 1993 | Ann. N. Y. Acad. Sci. | pmid:8352442 |
| Scheurlen M et al. | Fish oil preparations rich in docosahexaenoic acid modify platelet responsiveness to prostaglandin-endoperoxide/thromboxane A2 receptor agonists. | 1993 | Biochem. Pharmacol. | pmid:8347146 |
| Clark WF et al. | Dietary protein restriction versus fish oil supplementation in the chronic remnant nephron model. | 1993 | Clin. Nephrol. | pmid:8334756 |
| Moore SA | Cerebral endothelium and astrocytes cooperate in supplying docosahexaenoic acid to neurons. | 1993 | Adv. Exp. Med. Biol. | pmid:8333338 |
| Martinez M et al. | Docosahexaenoic acid--a new therapeutic approach to peroxisomal-disorder patients: experience with two cases. | 1993 | Neurology | pmid:8327143 |
| Gordon WC and Bazan NG | Visualization of [3H]docosahexaenoic acid trafficking through photoreceptors and retinal pigment epithelium by electron microscopic autoradiography. | 1993 | Invest. Ophthalmol. Vis. Sci. | pmid:8325748 |
| Swinbanks D | Fish-oil miracle additive brings benefits to some. | 1993 | Nature | pmid:8321302 |
| Yeh YY et al. | Maternal dietary fish oil enriches docosahexaenoate levels in brain subcellular fractions of offspring. | 1993 | J. Neurosci. Res. | pmid:8320752 |
| Carlson SE et al. | Visual-acuity development in healthy preterm infants: effect of marine-oil supplementation. | 1993 | Am. J. Clin. Nutr. | pmid:8317386 |
| Bazan NG et al. | Pathways for the uptake and conservation of docosahexaenoic acid in photoreceptors and synapses: biochemical and autoradiographic studies. | 1993 | Can. J. Physiol. Pharmacol. | pmid:8313233 |
| Arbuckle LD et al. | Formula 18:2(n-6) and 18:3(n-3) content and ratio influence long-chain polyunsaturated fatty acids in the developing piglet liver and central nervous system. | 1994 | J. Nutr. | pmid:8308579 |
| Rossi E and Costa M | Fish oil derivatives as a prophylaxis of recurrent miscarriage associated with antiphospholipid antibodies (APL): a pilot study. | 1993 | Lupus | pmid:8305926 |
| Danno K et al. | Anti-inflammatory effects of eicosapentaenoic acid on experimental skin inflammation models. | 1993 | Arch. Dermatol. Res. | pmid:8304784 |
| Mundal HH et al. | The effect of N-3 fatty acids and nifedipine on platelet function in hypertensive males. | 1993 | Thromb. Res. | pmid:8303664 |
| Matsumoto K et al. | Inhibitory effect of docosahexaenoic acid-containing phospholipids on 5-lipoxygenase in rat basophilic leukemia cells. | 1993 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:8302921 |
| Neuringer M | Cerebral cortex docosahexaenoic acid is lower in formula-fed than in breast-fed infants. | 1993 | Nutr. Rev. | pmid:8302494 |
| Chin JP et al. | Indomethacin inhibits the effects of dietary supplementation with marine oils on vasoconstriction of human forearm resistance vessels in vivo. | 1993 | J. Hypertens. | pmid:8301104 |
| Sanjurjo P et al. | Cross-sectional study of percentual changes in total plasmatic fatty acids during pregnancy. | 1993 | Horm. Metab. Res. | pmid:8288163 |
| Makrides M et al. | The effect of dietary fat on the developing brain. | 1993 | J Paediatr Child Health | pmid:8286154 |
| Kuklev DV et al. | [Synthesis of monoepoxides of arachidonic, eicosapentaenoic, and docosahexaenoic acids]. | 1993 | Bioorg. Khim. | pmid:8285925 |
| Chen Q et al. | Digestion of triacylglycerols containing long-chain polyenoic fatty acids in vitro by colipase-dependent pancreatic lipase and human milk bile salt-stimulated lipase. | 1994 | Biochim. Biophys. Acta | pmid:8280776 |
| Ettinger WH et al. | Cytokines decrease apolipoprotein accumulation in medium from Hep G2 cells. | 1994 | Arterioscler. Thromb. | pmid:8274481 |
| Chen H and Anderson RE | Differential incorporation of docosahexaenoic and arachidonic acids in frog retinal pigment epithelium. | 1993 | J. Lipid Res. | pmid:8263418 |
| Richard MJ et al. | Relationship of omega-3 fatty acid supplementation to plasma lipid peroxidation in predialysis patients with hypertriglyceridaemia. | 1993 | Eur J Med | pmid:8257999 |
| Fowler KH et al. | Purified dietary n-3 polyunsaturated fatty acids alter diacylglycerol mass and molecular species composition in concanavalin A-stimulated murine splenocytes. | 1993 | Biochim. Biophys. Acta | pmid:8257724 |
| Marangoni F et al. | Changes of n-3 and n-6 fatty acids in plasma and circulating cells of normal subjects, after prolonged administration of 20:5 (EPA) and 22:6 (DHA) ethyl esters and prolonged washout. | 1993 | Biochim. Biophys. Acta | pmid:8257719 |
| Farquharson J et al. | Effect of diet on infant subcutaneous tissue triglyceride fatty acids. | 1993 | Arch. Dis. Child. | pmid:8257182 |
| Reynaud D et al. | Facile preparation and structural determination of monohydroxy derivatives of docosahexaenoic acid (HDoHE) by alpha-tocopherol-directed autoxidation. | 1993 | Anal. Biochem. | pmid:8250220 |
| Bates EJ et al. | Docosahexanoic acid (22:6, n-3) but not eicosapentaenoic acid (20:5, n-3) can induce neutrophil-mediated injury of cultured endothelial cells: involvement of neutrophil elastase. | 1993 | J. Leukoc. Biol. | pmid:8245712 |
| Subbaiah PV et al. | Incorporation of dietary n-3 fatty acids into molecular species of phosphatidyl choline and cholesteryl ester in normal human plasma. | 1993 | Am. J. Clin. Nutr. | pmid:8237847 |
| Sumida C et al. | Interaction of unsaturated fatty acids with rat liver glucocorticoid receptors: studies to localize the site of interaction. | 1993 | Acta Endocrinol. | pmid:8237254 |
| Schmitt Y and Schneider H | [The effect of highly unsaturated fatty acids on the parameters of lipoprotein metabolism and rheology during their administration to patients undergoing chronic hemodialysis treatment]. | 1993 | Z Ernahrungswiss | pmid:8237080 |
| Kanazawa A and Fujimoto K | Effects of endogenous and exogenous n-3 and n-6 fatty acids on microsomal synthesis of docosahexaenoic acid in vitro. | 1993 | J. Nutr. Sci. Vitaminol. | pmid:8229317 |
| Fowler KH et al. | Effects of purified dietary n-3 ethyl esters on murine T lymphocyte function. | 1993 | J. Immunol. | pmid:8228217 |
| Maldjian A et al. | The transfer of docosahexaenoic acid from the yolk to the tissues of the chick embryo. | 1993 | Biochem. Soc. Trans. | pmid:8224445 |
| Chen H and Anderson RE | Metabolism in frog retinal pigment epithelium of docosahexaenoic and arachidonic acids derived from rod outer segment membranes. | 1993 | Exp. Eye Res. | pmid:8224024 |
| Lau CS et al. | Effects of fish oil supplementation on non-steroidal anti-inflammatory drug requirement in patients with mild rheumatoid arthritis--a double-blind placebo controlled study. | 1993 | Br. J. Rheumatol. | pmid:8220938 |
| Chen Y et al. | Interactions of all-trans-retinol and long-chain fatty acids with interphotoreceptor retinoid-binding protein. | 1993 | Biochemistry | pmid:8218196 |
| Houston L | Dietary change in arthritis. | 1994 | Practitioner | pmid:8208662 |
| Sawazaki S et al. | Lipoxygenation of docosahexaenoic acid by the rat pineal body. | 1994 | J. Neurochem. | pmid:8189247 |
| Joulain C et al. | Increased glutathione peroxidase activity in human blood mononuclear cells upon in vitro incubation with n-3 fatty acids. | 1994 | Biochem. Pharmacol. | pmid:8185640 |
| Billman GE et al. | Prevention of ischemia-induced ventricular fibrillation by omega 3 fatty acids. | 1994 | Proc. Natl. Acad. Sci. U.S.A. | pmid:8183925 |
| Calderaro V et al. | Docosahexaenoic acid and signaling pathways in rabbit colon. | 1994 | Mol. Pharmacol. | pmid:8183254 |