DHA
Dha is a lipid of Fatty Acyls (FA) class. Dha is associated with abnormalities such as Atherosclerosis, Consumption-archaic term for TB, Chronic disease, Cardiovascular Diseases and Diabetes Mellitus, Non-Insulin-Dependent. The involved functions are known as Inflammation, Oxidation, fatty acid oxidation, Fatty Acid Metabolism and Lipid Metabolism. Dha often locates in Hepatic, Protoplasm, Mucous Membrane, Epithelium and outer membrane. The associated genes with DHA are IMPACT gene, FATE1 gene, GAPDH gene, THOC4 gene and SLC33A1 gene. The related lipids are stearidonic acid, Fatty Acids, Total cholesterol, Lipopolysaccharides and Dietary Fatty Acid. The related experimental models are Mouse Model, Transgenic Model, Animal Disease Models and Arthritis, Experimental.
Cross Reference
Introduction
To understand associated biological information of DHA, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with DHA?
DHA is suspected in Cardiovascular Diseases, Obesity, Ischemia, Hypertensive disease, Coronary Arteriosclerosis, Cerebrovascular accident and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with DHA
PubChem Associated disorders and diseases
What pathways are associated with DHA
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with DHA?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with DHA?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with DHA?
Related references are published most in these journals:
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What genes are associated with DHA?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with DHA?
Mouse Model
Mouse Model are used in the study 'Homeostatic regulation of photoreceptor cell integrity: significance of the potent mediator neuroprotectin D1 biosynthesized from docosahexaenoic acid: the Proctor Lecture.' (Bazan NG, 2007), Mouse Model are used in the study 'Omega-3 fatty acids EPA and DHA: health benefits throughout life.' (Swanson D et al., 2012), Mouse Model are used in the study 'Docosahexaenoic acid attenuates hepatic inflammation, oxidative stress, and fibrosis without decreasing hepatosteatosis in a Ldlr(-/-) mouse model of western diet-induced nonalcoholic steatohepatitis.' (Depner CM et al., 2013) and Mouse Model are used in the study 'Wax esters from the marine copepod Calanus finmarchicus reduce diet-induced obesity and obesity-related metabolic disorders in mice.' (Höper AC et al., 2014).
Transgenic Model
Transgenic Model are used in the study 'Loss of MAP function leads to hippocampal synapse loss and deficits in the Morris Water Maze with aging.' (Ma QL et al., 2014).
Animal Disease Models
Animal Disease Models are used in the study 'Fish oil increases muscle protein mass and modulates Akt/FOXO, TLR4, and NOD signaling in weanling piglets after lipopolysaccharide challenge.' (Liu Y et al., 2013).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
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NCBI Entrez Crosslinks
All references with DHA
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Gilbert K et al. | Resolvin D1, a metabolite of omega-3 polyunsaturated fatty acid, decreases post-myocardial infarct depression. | 2014 | Mar Drugs | pmid:25402828 |
| Bremer AA et al. | Fish oil supplementation ameliorates fructose-induced hypertriglyceridemia and insulin resistance in adult male rhesus macaques. | 2014 | J. Nutr. | pmid:24108131 |
| Papanikolaou Y et al. | U.S. adults are not meeting recommended levels for fish and omega-3 fatty acid intake: results of an analysis using observational data from NHANES 2003-2008. | 2014 | Nutr J | pmid:24694001 |
| Ottosson NE et al. | Drug-induced ion channel opening tuned by the voltage sensor charge profile. | 2014 | J. Gen. Physiol. | pmid:24420769 |
| Hong SH et al. | Docosahexaenoic acid confers enduring neuroprotection in experimental stroke. | 2014 | J. Neurol. Sci. | pmid:24433927 |
| Marklund M et al. | A dietary biomarker approach captures compliance and cardiometabolic effects of a healthy Nordic diet in individuals with metabolic syndrome. | 2014 | J. Nutr. | pmid:25080537 |
| Domenichiello AF et al. | Whole body synthesis rates of DHA from α-linolenic acid are greater than brain DHA accretion and uptake rates in adult rats. | 2014 | J. Lipid Res. | pmid:24212299 |
| Di Gregorio E et al. | ELOVL5 mutations cause spinocerebellar ataxia 38. | 2014 | Am. J. Hum. Genet. | pmid:25065913 |
| Sokolov EI et al. | [Value of Fatty acids in formation of thrombotic status in patients with ischemic heart disease]. | 2014 | Kardiologiia | pmid:25177882 |
| Aslan M et al. | A pilot study investigating early postoperative changes of plasma polyunsaturated fatty acids after laparoscopic sleeve gastrectomy. | 2014 | Lipids Health Dis | pmid:24694037 |
| Dai XW et al. | Erythrocyte membrane n-3 fatty acid levels and carotid atherosclerosis in Chinese men and women. | 2014 | Atherosclerosis | pmid:24401220 |
| Aursnes M et al. | Total synthesis of the lipid mediator PD1n-3 DPA: configurational assignments and anti-inflammatory and pro-resolving actions. | 2014 | J. Nat. Prod. | pmid:24576195 |
| Arnold C et al. | Regarding macular xanthophylls and ω-3 long-chain polyunsaturated fatty acids in age-related macular degeneration--reply. | 2014 | JAMA Ophthalmol | pmid:24525936 |
| Brasky TM et al. | Associations of long-chain ω-3 fatty acids and fish intake with endometrial cancer risk in the VITamins And Lifestyle cohort. | 2014 | Am. J. Clin. Nutr. | pmid:24500149 |
| Li X et al. | Production of structured phosphatidylcholine with high content of DHA/EPA by immobilized phospholipase Aâ‚-catalyzed transesterification. | 2014 | Int J Mol Sci | pmid:25170810 |
| Colas RA et al. | Identification and signature profiles for pro-resolving and inflammatory lipid mediators in human tissue. | 2014 | Am. J. Physiol., Cell Physiol. | pmid:24696140 |
| Liu Y et al. | The fish oil ingredient, docosahexaenoic acid, activates cytosolic phospholipase Aâ‚‚ via GPR120 receptor to produce prostaglandin Eâ‚‚ and plays an anti-inflammatory role in macrophages. | 2014 | Immunology | pmid:24673159 |
| Zhang B et al. | Polyunsaturated fatty acids for the prevention of atrial fibrillation after cardiac surgery: an updated meta-analysis of randomized controlled trials. | 2014 | J Cardiol | pmid:23911138 |
| Liu M et al. | Protectin DX, a double lipoxygenase product of DHA, inhibits both ROS production in human neutrophils and cyclooxygenase activities. | 2014 | Lipids | pmid:24254970 |
| James MJ et al. | Pitfalls in the use of randomised controlled trials for fish oil studies with cardiac patients. | 2014 | Br. J. Nutr. | pmid:24933212 |