DHA

Dha is a lipid of Fatty Acyls (FA) class. Dha is associated with abnormalities such as Atherosclerosis, Consumption-archaic term for TB, Chronic disease, Cardiovascular Diseases and Diabetes Mellitus, Non-Insulin-Dependent. The involved functions are known as Inflammation, Oxidation, fatty acid oxidation, Fatty Acid Metabolism and Lipid Metabolism. Dha often locates in Hepatic, Protoplasm, Mucous Membrane, Epithelium and outer membrane. The associated genes with DHA are IMPACT gene, FATE1 gene, GAPDH gene, THOC4 gene and SLC33A1 gene. The related lipids are stearidonic acid, Fatty Acids, Total cholesterol, Lipopolysaccharides and Dietary Fatty Acid. The related experimental models are Mouse Model, Transgenic Model, Animal Disease Models and Arthritis, Experimental.

Cross Reference

Introduction

To understand associated biological information of DHA, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with DHA?

DHA is suspected in Cardiovascular Diseases, Obesity, Ischemia, Hypertensive disease, Coronary Arteriosclerosis, Cerebrovascular accident and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with DHA

MeSH term MeSH ID Detail
Dysbiosis D064806 2 associated lipids
Chronic Pain D059350 5 associated lipids
Peripheral Nerve Injuries D059348 6 associated lipids
Peripheral Arterial Disease D058729 7 associated lipids
Plaque, Atherosclerotic D058226 7 associated lipids
Plaque, Amyloid D058225 19 associated lipids
Acute Kidney Injury D058186 34 associated lipids
Geographic Atrophy D057092 1 associated lipids
Acute Lung Injury D055371 33 associated lipids
Precursor T-Cell Lymphoblastic Leukemia-Lymphoma D054218 5 associated lipids
Acute Coronary Syndrome D054058 11 associated lipids
Hypercalciuria D053565 4 associated lipids
Refsum Disease, Infantile D052919 1 associated lipids
Histiocytoma, Malignant Fibrous D051677 1 associated lipids
Atherosclerosis D050197 85 associated lipids
Dyslipidemias D050171 7 associated lipids
Decapitation D049248 2 associated lipids
Diabetes Complications D048909 4 associated lipids
Premature Birth D047928 6 associated lipids
Malnutrition D044342 6 associated lipids
Metabolic Syndrome D024821 44 associated lipids
Hypoxia-Ischemia, Brain D020925 22 associated lipids
Dyskinesias D020820 3 associated lipids
Spinocerebellar Ataxias D020754 4 associated lipids
Parkinsonian Disorders D020734 20 associated lipids
Multiple Sclerosis, Relapsing-Remitting D020529 7 associated lipids
Stroke D020521 32 associated lipids
Brain Infarction D020520 17 associated lipids
Muscular Dystrophy, Duchenne D020388 11 associated lipids
Intracranial Hemorrhages D020300 2 associated lipids
Neurotoxicity Syndromes D020258 34 associated lipids
Infarction, Middle Cerebral Artery D020244 35 associated lipids
Cerebrovascular Trauma D020214 1 associated lipids
Sleep Apnea, Obstructive D020181 9 associated lipids
Genetic Predisposition to Disease D020022 24 associated lipids
Neurodegenerative Diseases D019636 32 associated lipids
Neuroaxonal Dystrophies D019150 3 associated lipids
Burkholderia Infections D019121 7 associated lipids
Depression, Postpartum D019052 3 associated lipids
Chondrodysplasia Punctata, Rhizomelic D018902 4 associated lipids
Peroxisomal Disorders D018901 5 associated lipids
Carcinoma, Lewis Lung D018827 22 associated lipids
Sepsis D018805 11 associated lipids
Ventricular Dysfunction, Left D018487 33 associated lipids
Pneumonia, Bacterial D018410 16 associated lipids
Trophoblastic Tumor, Placental Site D018245 1 associated lipids
Carcinoma, Embryonal D018236 8 associated lipids
Glucose Intolerance D018149 13 associated lipids
Phenylketonuria, Maternal D017042 1 associated lipids
Keratitis, Herpetic D016849 5 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with DHA

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with DHA?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with DHA?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with DHA?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with DHA?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with DHA?

Mouse Model

Mouse Model are used in the study 'Homeostatic regulation of photoreceptor cell integrity: significance of the potent mediator neuroprotectin D1 biosynthesized from docosahexaenoic acid: the Proctor Lecture.' (Bazan NG, 2007), Mouse Model are used in the study 'Omega-3 fatty acids EPA and DHA: health benefits throughout life.' (Swanson D et al., 2012), Mouse Model are used in the study 'Docosahexaenoic acid attenuates hepatic inflammation, oxidative stress, and fibrosis without decreasing hepatosteatosis in a Ldlr(-/-) mouse model of western diet-induced nonalcoholic steatohepatitis.' (Depner CM et al., 2013) and Mouse Model are used in the study 'Wax esters from the marine copepod Calanus finmarchicus reduce diet-induced obesity and obesity-related metabolic disorders in mice.' (Höper AC et al., 2014).

Transgenic Model

Transgenic Model are used in the study 'Loss of MAP function leads to hippocampal synapse loss and deficits in the Morris Water Maze with aging.' (Ma QL et al., 2014).

Animal Disease Models

Animal Disease Models are used in the study 'Fish oil increases muscle protein mass and modulates Akt/FOXO, TLR4, and NOD signaling in weanling piglets after lipopolysaccharide challenge.' (Liu Y et al., 2013).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with DHA

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Per page 10 20 50 100 | Total 7336
Authors Title Published Journal PubMed Link
Lagarde M et al. Structure-function relationships of non-cyclic dioxygenase products from polyunsaturated fatty acids: poxytrins as a class of bioactive derivatives. 2014 Biochimie pmid:25223888
Gong J et al. Maresin 1 mitigates LPS-induced acute lung injury in mice. 2014 Br. J. Pharmacol. pmid:24697684
Li S et al. The targeting mechanism of DHA ligand and its conjugate with Gemcitabine for the enhanced tumor therapy. 2014 Oncotarget pmid:25004114
Arafiles KH et al. Value-added lipid production from brown seaweed biomass by two-stage fermentation using acetic acid bacterium and thraustochytrid. 2014 Appl. Microbiol. Biotechnol. pmid:25086614
Koutsos A et al. Greater impact of dietary fat manipulation than apolipoprotein E genotype on ex vivo cytokine production - insights from the SATgenε study. 2014 Cytokine pmid:24485322
Norris JM et al. Erythrocyte membrane docosapentaenoic acid levels are associated with islet autoimmunity: the Diabetes Autoimmunity Study in the Young. 2014 Diabetologia pmid:24240437
Yamanushi TT et al. Oral administration of eicosapentaenoic acid or docosahexaenoic acid modifies cardiac function and ameliorates congestive heart failure in male rats. 2014 J. Nutr. pmid:24523492
Meagher KA et al. Regarding macular xanthophylls and ω-3 long-chain polyunsaturated fatty acids in age-related macular degeneration. 2014 JAMA Ophthalmol pmid:24525935
Sánchez-Reyes OB et al. Free fatty acids and protein kinase C activation induce GPR120 (free fatty acid receptor 4) phosphorylation. 2014 Eur. J. Pharmacol. pmid:24239485
Paterniti I et al. Docosahexaenoic acid attenuates the early inflammatory response following spinal cord injury in mice: in-vivo and in-vitro studies. 2014 J Neuroinflammation pmid:24405628
Chen J et al. Aspirin-triggered resolvin D1 down-regulates inflammatory responses and protects against endotoxin-induced acute kidney injury. 2014 Toxicol. Appl. Pharmacol. pmid:24709673
Recchiuti A et al. Immunoresolving actions of oral resolvin D1 include selective regulation of the transcription machinery in resolution-phase mouse macrophages. 2014 FASEB J. pmid:24692596
Létondor A et al. Erythrocyte DHA level as a biomarker of DHA status in specific brain regions of n-3 long-chain PUFA-supplemented aged rats. 2014 Br. J. Nutr. pmid:25331622
Kermack AJ et al. A randomised controlled trial of a preconceptional dietary intervention in women undergoing IVF treatment (PREPARE trial). 2014 BMC Womens Health pmid:25407227
Wang JL et al. Preparation and characterization of novel lipid carriers containing microalgae oil for food applications. 2014 J. Food Sci. pmid:24446860
Giovannelli J et al. Validation of a short, qualitative food frequency questionnaire in French adults participating in the MONA LISA-NUT study 2005-2007. 2014 J Acad Nutr Diet pmid:24083967
Rius B et al. Resolvin D1 primes the resolution process initiated by calorie restriction in obesity-induced steatohepatitis. 2014 FASEB J. pmid:24249635
Choi EY et al. DHA suppresses Prevotella intermedia lipopolysaccharide-induced production of proinflammatory mediators in murine macrophages. 2014 Br. J. Nutr. pmid:24252501
Ponnampalam EN et al. Sources of variation of health claimable long chain omega-3 fatty acids in meat from Australian lamb slaughtered at similar weights. 2014 Meat Sci. pmid:23265412
Amiri-Jami M et al. Engineering of EPA/DHA omega-3 fatty acid production by Lactococcus lactis subsp. cremoris MG1363. 2014 Appl. Microbiol. Biotechnol. pmid:24389665