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2017 |
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Resolvin RvD2 reduces hypothalamic inflammation and rescues mice from diet-induced obesity. |
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J Neuroinflammation |
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2017 |
PLoS ONE |
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Molecular mechanisms of signaling via the docosanoid neuroprotectin D1 for cellular homeostasis and neuroprotection. |
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Dysfunctional GPR40/FFAR1 signaling exacerbates pain behavior in mice. |
2017 |
PLoS ONE |
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Dietary docosahexaenoic acid supplementation prevents the formation of cholesterol oxidation products in arteries from orchidectomized rats. |
2017 |
PLoS ONE |
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Maresin 1 Mitigates High Glucose-Induced Mouse Glomerular Mesangial Cell Injury by Inhibiting Inflammation and Fibrosis. |
2017 |
Mediators Inflamm. |
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N-Docosahexaenoyl Dopamine, an Endocannabinoid-like Conjugate of Dopamine and the n-3 Fatty Acid Docosahexaenoic Acid, Attenuates Lipopolysaccharide-Induced Activation of Microglia and Macrophages via COX-2. |
2017 |
ACS Chem Neurosci |
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2017 |
Biochim. Biophys. Acta |
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Comparison of the effects of major fatty acids present in the Mediterranean diet (oleic acid, docosahexaenoic acid) and in hydrogenated oils (elaidic acid) on 7-ketocholesterol-induced oxiapoptophagy in microglial BV-2 cells. |
2017 |
Chem. Phys. Lipids |
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Tailoring naringenin conjugates with amplified and triple antiplatelet activity profile: Rational design, synthesis, human plasma stability and in vitro evaluation. |
2017 |
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Carotenoids of Red, Brown, and Black Specimens of Plectropomus leopardus, the Coral Trout (Suziara in Japanese). |
2017 |
J Oleo Sci |
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Is cytotoxicity a determinant of the different in vitro and in vivo effects of bioactives? |
2017 |
BMC Complement Altern Med |
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Analysis of endogenous lipids during intestinal wound healing. |
2017 |
PLoS ONE |
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Activation of autophagy and PPARγ protect colon cancer cells against apoptosis induced by interactive effects of butyrate and DHA in a cell type-dependent manner: The role of cell differentiation. |
2017 |
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Determination of Substrate Preferences for Desaturases and Elongases for Production of Docosahexaenoic Acid from Oleic Acid in Engineered Canola. |
2017 |
Lipids |
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Dietary fatty acids specifically modulate phospholipid pattern in colon cells with distinct differentiation capacities. |
2017 |
Eur J Nutr |
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Docosahexaenoyl serotonin emerges as most potent inhibitor of IL-17 and CCL-20 released by blood mononuclear cells from a series of N-acyl serotonins identified in human intestinal tissue. |
2017 |
Biochim. Biophys. Acta |
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Dietary Buglossoides Arvensis Oil Increases Circulating n-3 Polyunsaturated Fatty Acids in a Dose-Dependent Manner and Enhances Lipopolysaccharide-Stimulated Whole Blood Interleukin-10-A Randomized Placebo-Controlled Trial. |
2017 |
Nutrients |
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Attenuation of 7-ketocholesterol-induced overproduction of reactive oxygen species, apoptosis, and autophagy by dimethyl fumarate on 158N murine oligodendrocytes. |
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J. Steroid Biochem. Mol. Biol. |
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Marine Oil Supplements for Arthritis Pain: A Systematic Review and Meta-Analysis of Randomized Trials. |
2017 |
Nutrients |
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Serum Fatty Acids, Desaturase Activities and Abdominal Obesity - A Population-Based Study of 60-Year Old Men and Women. |
2017 |
PLoS ONE |
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Probing the intermolecular interactions of PPARγ-LBD with polyunsaturated fatty acids and their anti-inflammatory metabolites to infer most potential binding moieties. |
2017 |
Lipids Health Dis |
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Resolvin D1 Increases Mucin Secretion in Cultured Rat Conjunctival Goblet Cells via Multiple Signaling Pathways. |
2017 |
Invest. Ophthalmol. Vis. Sci. |
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Anomalies occurring in lipid profiles and protein distribution in frontal cortex lipid rafts in dementia with Lewy bodies disclose neurochemical traits partially shared by Alzheimer's and Parkinson's diseases. |
2017 |
Neurobiol. Aging |
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Aspirin-triggered resolvin D1 attenuates PDGF-induced vascular smooth muscle cell migration via the cyclic adenosine monophosphate/protein kinase A (cAMP/PKA) pathway. |
2017 |
PLoS ONE |
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Milk protein-based formulas containing different oils affect fatty acids balance in term infants: A randomized blinded crossover clinical trial. |
2017 |
Lipids Health Dis |
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7-Ketocholesterol is increased in the plasma of X-ALD patients and induces peroxisomal modifications in microglial cells: Potential roles of 7-ketocholesterol in the pathophysiology of X-ALD. |
2017 |
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Pro-resolving lipid mediator Resolvin D1 serves as a marker of lung disease in cystic fibrosis. |
2017 |
PLoS ONE |
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Involvement of the endocannabinoid system in the physiological response to transient common carotid artery occlusion and reperfusion. |
2017 |
Lipids Health Dis |
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Regulation of the Docosapentaenoic Acid/Docosahexaenoic Acid Ratio (DPA/DHA Ratio) in Schizochytrium limacinum B4D1. |
2017 |
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Resolvin D1, resolvin D2 and maresin 1 activate the GSK3β anti-inflammatory axis in TLR4-engaged human monocytes. |
2016 |
Innate Immun |
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2016 |
Lab. Invest. |
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Resolvin D1 protects against inflammation in experimental acute pancreatitis and associated lung injury. |
2016 |
Am. J. Physiol. Gastrointest. Liver Physiol. |
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2016 |
Postgrad Med |
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Stretching Impacts Inflammation Resolution in Connective Tissue. |
2016 |
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Resolvin D2 decreases TLR4 expression to mediate resolution in human monocytes. |
2016 |
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Human milk proresolving mediators stimulate resolution of acute inflammation. |
2016 |
Mucosal Immunol |
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2016 |
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Abnormal fatty acids in Canadian children with autism. |
2016 |
Nutrition |
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Metabolic fate of docosahexaenoic acid (DHA; 22:6n-3) in human cells: direct retroconversion of DHA to eicosapentaenoic acid (20:5n-3) dominates over elongation to tetracosahexaenoic acid (24:6n-3). |
2016 |
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2016 |
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Circulating Omega-6, But Not Omega-3 Polyunsaturated Fatty Acids, Are Associated with Clinical Outcomes in Patients with Acute Decompensated Heart Failure. |
2016 |
PLoS ONE |
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Omega-3 fatty acids control productions of superoxide and nitrogen oxide and insulin content in INS-1E cells. |
2016 |
J. Physiol. Biochem. |
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Maresin 1 Mitigates Inflammatory Response and Protects Mice from Sepsis. |
2016 |
Mediators Inflamm. |
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Maresin 1, a Proresolving Lipid Mediator, Mitigates Carbon Tetrachloride-Induced Liver Injury in Mice. |
2016 |
Oxid Med Cell Longev |
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The clinical benefits of long-term supplementation with omega-3 fatty acids in cystic fibrosis patients - A pilot study. |
2016 |
Prostaglandins Leukot. Essent. Fatty Acids |
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Epigenomic maintenance through dietary intervention can facilitate DNA repair process to slow down the progress of premature aging. |
2016 |
IUBMB Life |
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Biological relevance of fatty acyl heterogeneity to the neural membrane dynamics of rhesus macaques during normative aging. |
2016 |
Oncotarget |
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Enhanced incorporation of dietary DHA into lymph phospholipids by altering its molecular carrier. |
2016 |
Biochim. Biophys. Acta |
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Omega-3 Fatty Acid Formulations in Cardiovascular Disease: Dietary Supplements are Not Substitutes for Prescription Products. |
2016 |
Am J Cardiovasc Drugs |
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A randomized, crossover, head-to-head comparison of eicosapentaenoic acid and docosahexaenoic acid supplementation to reduce inflammation markers in men and women: the Comparing EPA to DHA (ComparED) Study. |
2016 |
Am. J. Clin. Nutr. |
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2016 |
Prostaglandins Leukot. Essent. Fatty Acids |
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Human apolipoprotein E allele and docosahexaenoic acid intake modulate peripheral cholesterol homeostasis in mice. |
2016 |
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Potential serum biomarkers from a metabolomics study of autism. |
2016 |
J Psychiatry Neurosci |
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iPLA2β deficiency attenuates obesity and hepatic steatosis in ob/ob mice through hepatic fatty-acyl phospholipid remodeling. |
2016 |
Biochim. Biophys. Acta |
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Enhanced anti-inflammatory effects of DHA and quercetin in lipopolysaccharide-induced RAW264.7 macrophages by inhibiting NF-κB and MAPK activation. |
2016 |
Mol Med Rep |
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Bioconversion of Docosapentaenoic Acid in Human Cell Lines, Caco-2, HepG2, and THP-1. |
2016 |
J Oleo Sci |
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Chimeric Glutamate Receptor Subunits Reveal the Transmembrane Domain Is Sufficient for NMDA Receptor Pore Properties but Some Positive Allosteric Modulators Require Additional Domains. |
2016 |
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Maternal DHA supplementation protects rat offspring against impairment of learning and memory following prenatal exposure to valproic acid. |
2016 |
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Docosahexaenoic acid and palmitic acid reciprocally modulate monocyte activation in part through endoplasmic reticulum stress. |
2016 |
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Synthesis of 13(R)-Hydroxy-7Z,10Z,13R,14E,16Z,19Z Docosapentaenoic Acid (13R-HDPA) and Its Biosynthetic Conversion to the 13-Series Resolvins. |
2016 |
J. Nat. Prod. |
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Treatment with DHA/EPA ameliorates atopic dermatitis-like skin disease by blocking LTB4 production. |
2016 |
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Brown but not white adipose cells synthesize omega-3 docosahexaenoic acid in culture. |
2016 |
Prostaglandins Leukot. Essent. Fatty Acids |
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Biohydrogenation of 22:6n-3 by Butyrivibrio proteoclasticus P18. |
2016 |
BMC Microbiol. |
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Astaxanthin and Docosahexaenoic Acid Reverse the Toxicity of the Maxi-K (BK) Channel Antagonist Mycotoxin Penitrem A. |
2016 |
Mar Drugs |
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High Fat Diet Administration during Specific Periods of Pregnancy Alters Maternal Fatty Acid Profiles in the Near-Term Rat. |
2016 |
Nutrients |
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Identification of Novel Genetic Determinants of Erythrocyte Membrane Fatty Acid Composition among Greenlanders. |
2016 |
PLoS Genet. |
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The role of resolvin D1 in the regulation of inflammatory and catabolic mediators in osteoarthritis. |
2016 |
Inflamm. Res. |
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Levels of Red Blood Cell Fatty Acids in Patients With Psychosis, Their Unaffected Siblings, and Healthy Controls. |
2016 |
Schizophr Bull |
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Rise in DPA Following SDA-Rich Dietary Echium Oil Less Effective in Affording Anti-Arrhythmic Actions Compared to High DHA Levels Achieved with Fish Oil in Sprague-Dawley Rats. |
2016 |
Nutrients |
pmid:26742064
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Vitamin B Deficiency Across Three Generations Adversely Influences Long-chain Polyunsaturated Fatty Acid Status and Cardiometabolic Markers in Rats. |
2016 |
Arch. Med. Res. |
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Dietary saturated fatty acid and polyunsaturated fatty acid oppositely affect hepatic NOD-like receptor protein 3 inflammasome through regulating nuclear factor-kappa B activation. |
2016 |
World J. Gastroenterol. |
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Inhibitory effects of aspirin-triggered resolvin D1 on spinal nociceptive processing in rat pain models. |
2016 |
J Neuroinflammation |
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Induction of Gnrh mRNA expression by the ω-3 polyunsaturated fatty acid docosahexaenoic acid and the saturated fatty acid palmitate in a GnRH-synthesizing neuronal cell model, mHypoA-GnRH/GFP. |
2016 |
Mol. Cell. Endocrinol. |
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Regulation of the Omega-3 Fatty Acid Biosynthetic Pathway in Atlantic Salmon Hepatocytes. |
2016 |
PLoS ONE |
pmid:27973547
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Celecoxib, a COX-2 inhibitor, synergistically potentiates the anti-inflammatory activity of docosahexaenoic acid in macrophage cell line. |
2016 |
Immunopharmacol Immunotoxicol |
pmid:26954392
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Omega-3 Polyunsaturated Fatty Acids and Oxylipins in Neuroinflammation and Management of Alzheimer Disease. |
2016 |
Adv Nutr |
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Preliminary Validation of a High Docosahexaenoic Acid (DHA) and -Linolenic Acid (ALA) Dietary Oil Blend: Tissue Fatty Acid Composition and Liver Proteome Response in Atlantic Salmon (Salmo salar) Smolts. |
2016 |
PLoS ONE |
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ω-3 Polyunsaturated Fatty Acid Biomarkers and Coronary Heart Disease: Pooling Project of 19 Cohort Studies. |
2016 |
JAMA Intern Med |
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Whole-body DHA synthesis-secretion kinetics from plasma eicosapentaenoic acid and alpha-linolenic acid in the free-living rat. |
2016 |
Biochim. Biophys. Acta |
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Pro-Resolving Effects of Resolvin D2 in LTD4 and TNF-α Pre-Treated Human Bronchi. |
2016 |
PLoS ONE |
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Asymmetric Binding and Metabolism of Polyunsaturated Fatty Acids (PUFAs) by CYP2J2 Epoxygenase. |
2016 |
Biochemistry |
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Impact of Genotype on EPA and DHA Status and Responsiveness to Increased Intakes. |
2016 |
Nutrients |
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Threshold changes in rat brain docosahexaenoic acid incorporation and concentration following graded reductions in dietary alpha-linolenic acid. |
2016 |
Prostaglandins Leukot. Essent. Fatty Acids |
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Long-chain unsaturated fatty acids reduce the transcriptional activity of the rat follicle-stimulating hormone β-subunit gene. |
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J. Reprod. Dev. |
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Mechanisms of DHA transport to the brain and potential therapy to neurodegenerative diseases. |
2016 |
Biochimie |
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AT-RvD1 combined with DEX is highly effective in treating TNF-α-mediated disruption of the salivary gland epithelium. |
2016 |
Physiol Rep |
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Meta-analysis of erythrocyte polyunsaturated fatty acid biostatus in bipolar disorder. |
2016 |
Bipolar Disord |
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Signaling and Immunoresolving Actions of Resolvin D1 in Inflamed Human Visceral Adipose Tissue. |
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J. Immunol. |
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ALX/FPR2 Modulates Anti-Inflammatory Responses in Mouse Submandibular Gland. |
2016 |
Sci Rep |
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Resolvin D1 Programs Inflammation Resolution by Increasing TGF-β Expression Induced by Dying Cell Clearance in Experimental Autoimmune Neuritis. |
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Dietary DHA supplementation causes selective changes in phospholipids from different brain regions in both wild type mice and the Tg2576 mouse model of Alzheimer's disease. |
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Biochim. Biophys. Acta |
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Resolvin D1 Alleviates the Lung Ischemia Reperfusion Injury via Complement, Immunoglobulin, TLR4, and Inflammatory Factors in Rats. |
2016 |
Inflammation |
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VIP protects human retinal microvascular endothelial cells against high glucose-induced increases in TNF-α and enhances RvD1. |
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Prostaglandins Other Lipid Mediat. |
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Resolvin D1 Polarizes Primary Human Macrophages toward a Proresolution Phenotype through GPR32. |
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