| MeSH term | MeSH ID | Detail |
|---|---|---|
| Autoimmune Diseases | D001327 | 27 associated lipids |
| Atrial Fibrillation | D001281 | 16 associated lipids |
| Asthma, Exercise-Induced | D001250 | 10 associated lipids |
| Asthma | D001249 | 52 associated lipids |
| Arthus Reaction | D001183 | 8 associated lipids |
| Arteriosclerosis | D001161 | 86 associated lipids |
| Arrhythmias, Cardiac | D001145 | 42 associated lipids |
| Aortic Diseases | D001018 | 11 associated lipids |
| Hypoxia | D000860 | 23 associated lipids |
| Angina, Unstable | D000789 | 14 associated lipids |
| Angina Pectoris | D000787 | 27 associated lipids |
| Anemia, Sickle Cell | D000755 | 34 associated lipids |
| Anemia | D000740 | 21 associated lipids |
| Anaphylaxis | D000707 | 35 associated lipids |
| Alzheimer Disease | D000544 | 76 associated lipids |
| Albinism | D000417 | 3 associated lipids |
| Adrenoleukodystrophy | D000326 | 29 associated lipids |
| Adenocarcinoma | D000230 | 166 associated lipids |
| Acquired Immunodeficiency Syndrome | D000163 | 12 associated lipids |
| Abortion, Habitual | D000026 | 5 associated lipids |
DHA
Dha is a lipid of Fatty Acyls (FA) class. Dha is associated with abnormalities such as Atherosclerosis, Consumption-archaic term for TB, Chronic disease, Cardiovascular Diseases and Diabetes Mellitus, Non-Insulin-Dependent. The involved functions are known as Inflammation, Oxidation, fatty acid oxidation, Fatty Acid Metabolism and Lipid Metabolism. Dha often locates in Hepatic, Protoplasm, Mucous Membrane, Epithelium and outer membrane. The associated genes with DHA are IMPACT gene, FATE1 gene, GAPDH gene, THOC4 gene and SLC33A1 gene. The related lipids are stearidonic acid, Fatty Acids, Total cholesterol, Lipopolysaccharides and Dietary Fatty Acid. The related experimental models are Mouse Model, Transgenic Model, Animal Disease Models and Arthritis, Experimental.
Cross Reference
Introduction
To understand associated biological information of DHA, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with DHA?
DHA is suspected in Cardiovascular Diseases, Obesity, Ischemia, Hypertensive disease, Coronary Arteriosclerosis, Cerebrovascular accident and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with DHA
PubChem Associated disorders and diseases
What pathways are associated with DHA
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with DHA?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with DHA?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with DHA?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with DHA?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with DHA?
Mouse Model
Mouse Model are used in the study 'Homeostatic regulation of photoreceptor cell integrity: significance of the potent mediator neuroprotectin D1 biosynthesized from docosahexaenoic acid: the Proctor Lecture.' (Bazan NG, 2007), Mouse Model are used in the study 'Omega-3 fatty acids EPA and DHA: health benefits throughout life.' (Swanson D et al., 2012), Mouse Model are used in the study 'Docosahexaenoic acid attenuates hepatic inflammation, oxidative stress, and fibrosis without decreasing hepatosteatosis in a Ldlr(-/-) mouse model of western diet-induced nonalcoholic steatohepatitis.' (Depner CM et al., 2013) and Mouse Model are used in the study 'Wax esters from the marine copepod Calanus finmarchicus reduce diet-induced obesity and obesity-related metabolic disorders in mice.' (Höper AC et al., 2014).
Transgenic Model
Transgenic Model are used in the study 'Loss of MAP function leads to hippocampal synapse loss and deficits in the Morris Water Maze with aging.' (Ma QL et al., 2014).
Animal Disease Models
Animal Disease Models are used in the study 'Fish oil increases muscle protein mass and modulates Akt/FOXO, TLR4, and NOD signaling in weanling piglets after lipopolysaccharide challenge.' (Liu Y et al., 2013).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
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NCBI Entrez Crosslinks
All references with DHA
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Williard DE et al. | Comparison of 20-, 22-, and 24-carbon n-3 and n-6 polyunsaturated fatty acid utilization in differentiated rat brain astrocytes. | 2002 Aug-Sep | Prostaglandins Leukot. Essent. Fatty Acids | pmid:12324227 |
| Martin RE et al. | Docosahexaenoic, arachidonic, palmitic, and oleic acids are differentially esterified into phospholipids of frog retina. | 2002 Aug-Sep | Prostaglandins Leukot. Essent. Fatty Acids | pmid:12324228 |
| Sayanova O and Napier JA | Transgenic oilseed crops as an alternative to fish oils. | 2011 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:21596549 |
| Al-Turkmani MR et al. | Fatty acid alterations and n-3 fatty acid supplementation in cystic fibrosis. | 2007 Nov-Dec | Prostaglandins Leukot. Essent. Fatty Acids | pmid:18036797 |
| Brenna T et al. | Docosahexaenoic acid in translational medicine: the Tenth Fatty Acids and Cell Signaling meeting (FACS-10). | 2013 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:23103099 |
| Hashimoto M et al. | Effects of aging on the relation of adenyl purine release with plasma membrane fluidity of arterial endothelial cells. | 2005 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:16165346 |
| Gow RV et al. | Total red blood cell concentrations of omega-3 fatty acids are associated with emotion-elicited neural activity in adolescent boys with attention-deficit hyperactivity disorder. | 2009 Feb-Mar | Prostaglandins Leukot. Essent. Fatty Acids | pmid:19230637 |
| Bazan NG | Cellular and molecular events mediated by docosahexaenoic acid-derived neuroprotectin D1 signaling in photoreceptor cell survival and brain protection. | 2009 Aug-Sep | Prostaglandins Leukot. Essent. Fatty Acids | pmid:19520558 |
| Hsieh AT and Brenna JT | Dietary docosahexaenoic acid but not arachidonic acid influences central nervous system fatty acid status in baboon neonates. | 2009 Aug-Sep | Prostaglandins Leukot. Essent. Fatty Acids | pmid:19524425 |
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| Makrides M | Is there a dietary requirement for DHA in pregnancy? | 2009 Aug-Sep | Prostaglandins Leukot. Essent. Fatty Acids | pmid:19500960 |
| Schuchardt JP et al. | Moderate doses of EPA and DHA from re-esterified triacylglycerols but not from ethyl-esters lower fasting serum triacylglycerols in statin-treated dyslipidemic subjects: Results from a six month randomized controlled trial. | 2011 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:21862301 |
| Nieminen LR et al. | Relationship between omega-3 fatty acids and plasma neuroactive steroids in alcoholism, depression and controls. | 2006 Oct-Nov | Prostaglandins Leukot. Essent. Fatty Acids | pmid:16959481 |
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| Pakala R et al. | Serotonin-induced endothelial cell proliferation is blocked by omega-3 fatty acids. | 1999 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:10328332 |
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| Bazan NG | The docosanoid neuroprotectin D1 induces homeostatic regulation of neuroinflammation and cell survival. | 2013 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:23022417 |
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| Otto SJ et al. | The effect of supplementation with docosahexaenoic and arachidonic acid derived from single cell oils on plasma and erythrocyte fatty acids of pregnant women in the second trimester. | 2000 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:11090260 |
| Bell JG et al. | Growth, mortality, tissue histopathology and fatty acid compositions, eicosanoid production and response to stress, in juvenile turbot fed diets rich in gamma-linolenic acid in combination with eicosapentaenoic acid or docosahexaenoic acid. | 1998 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:9690713 |
| Huang LL et al. | Suppression of acute ethanol-induced hepatic steatosis by docosahexaenoic acid is associated with downregulation of stearoyl-CoA desaturase 1 and inflammatory cytokines. | 2013 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:23474173 |
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