| MeSH term | MeSH ID | Detail |
|---|---|---|
| Vibrio Infections | D014735 | 5 associated lipids |
| Vision Disorders | D014786 | 10 associated lipids |
| Vitamin E Deficiency | D014811 | 29 associated lipids |
| Dementia, Vascular | D015140 | 7 associated lipids |
| Colorectal Neoplasms | D015179 | 10 associated lipids |
| Zellweger Syndrome | D015211 | 39 associated lipids |
| Dry Eye Syndromes | D015352 | 10 associated lipids |
| Reperfusion Injury | D015427 | 65 associated lipids |
| Myocardial Reperfusion Injury | D015428 | 20 associated lipids |
| Weight Gain | D015430 | 101 associated lipids |
DHA
Dha is a lipid of Fatty Acyls (FA) class. Dha is associated with abnormalities such as Atherosclerosis, Consumption-archaic term for TB, Chronic disease, Cardiovascular Diseases and Diabetes Mellitus, Non-Insulin-Dependent. The involved functions are known as Inflammation, Oxidation, fatty acid oxidation, Fatty Acid Metabolism and Lipid Metabolism. Dha often locates in Hepatic, Protoplasm, Mucous Membrane, Epithelium and outer membrane. The associated genes with DHA are IMPACT gene, FATE1 gene, GAPDH gene, THOC4 gene and SLC33A1 gene. The related lipids are stearidonic acid, Fatty Acids, Total cholesterol, Lipopolysaccharides and Dietary Fatty Acid. The related experimental models are Mouse Model, Transgenic Model, Animal Disease Models and Arthritis, Experimental.
Cross Reference
Introduction
To understand associated biological information of DHA, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with DHA?
DHA is suspected in Cardiovascular Diseases, Obesity, Ischemia, Hypertensive disease, Coronary Arteriosclerosis, Cerebrovascular accident and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with DHA
PubChem Associated disorders and diseases
What pathways are associated with DHA
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with DHA?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with DHA?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with DHA?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with DHA?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with DHA?
Mouse Model
Mouse Model are used in the study 'Homeostatic regulation of photoreceptor cell integrity: significance of the potent mediator neuroprotectin D1 biosynthesized from docosahexaenoic acid: the Proctor Lecture.' (Bazan NG, 2007), Mouse Model are used in the study 'Omega-3 fatty acids EPA and DHA: health benefits throughout life.' (Swanson D et al., 2012), Mouse Model are used in the study 'Docosahexaenoic acid attenuates hepatic inflammation, oxidative stress, and fibrosis without decreasing hepatosteatosis in a Ldlr(-/-) mouse model of western diet-induced nonalcoholic steatohepatitis.' (Depner CM et al., 2013) and Mouse Model are used in the study 'Wax esters from the marine copepod Calanus finmarchicus reduce diet-induced obesity and obesity-related metabolic disorders in mice.' (Höper AC et al., 2014).
Transgenic Model
Transgenic Model are used in the study 'Loss of MAP function leads to hippocampal synapse loss and deficits in the Morris Water Maze with aging.' (Ma QL et al., 2014).
Animal Disease Models
Animal Disease Models are used in the study 'Fish oil increases muscle protein mass and modulates Akt/FOXO, TLR4, and NOD signaling in weanling piglets after lipopolysaccharide challenge.' (Liu Y et al., 2013).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
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NCBI Entrez Crosslinks
All references with DHA
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Agren JJ et al. | Hemostatic factors and platelet aggregation after a fish-enriched diet or fish oil or docosahexaenoic acid supplementation. | 1997 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:9430389 |
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| Chen ZY and Istfan NW | Docosahexaenoic acid, a major constituent of fish oil diets, prevents activation of cyclin-dependent kinases and S-phase entry by serum stimulation in HT-29 cells. | 2001 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:11161587 |
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| Lamaziere A et al. | Differential distribution of DHA-phospholipids in rat brain after feeding: A lipidomic approach. | 2011 Jan-Feb | Prostaglandins Leukot. Essent. Fatty Acids | pmid:21109411 |
| Kuipers RS et al. | Intrauterine, postpartum and adult relationships between arachidonic acid (AA) and docosahexaenoic acid (DHA). | 2011 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:21561751 |
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| Al-Turkmani MR et al. | Fatty acid alterations and n-3 fatty acid supplementation in cystic fibrosis. | 2007 Nov-Dec | Prostaglandins Leukot. Essent. Fatty Acids | pmid:18036797 |
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| MarÃn MC et al. | Dietary long-chain fatty acids and visual response in malnourished nursing infants. | 2000 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:11133176 |
| Hashimoto M et al. | Effects of aging on the relation of adenyl purine release with plasma membrane fluidity of arterial endothelial cells. | 2005 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:16165346 |
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| Chen ZY and Istfan NW | Docosahexaenoic acid is a potent inducer of apoptosis in HT-29 colon cancer cells. | 2000 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:11090257 |
| Bell JG et al. | Growth, mortality, tissue histopathology and fatty acid compositions, eicosanoid production and response to stress, in juvenile turbot fed diets rich in gamma-linolenic acid in combination with eicosapentaenoic acid or docosahexaenoic acid. | 1998 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:9690713 |
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| Russell KL et al. | Low brain DHA content worsens sensorimotor outcomes after TBI and decreases TBI-induced Timp1 expression in juvenile rats. | 2013 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:23796971 |
| Horrocks LA and Farooqui AA | Docosahexaenoic acid in the diet: its importance in maintenance and restoration of neural membrane function. | 2004 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:15041028 |
| Calderon F and Kim HY | Role of RXR in neurite outgrowth induced by docosahexaenoic acid. | 2007 Nov-Dec | Prostaglandins Leukot. Essent. Fatty Acids | pmid:18036800 |
| Kurowska EM et al. | Bioavailability of omega-3 essential fatty acids from perilla seed oil. | 2003 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:12591004 |
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| Plourde M et al. | Unresolved issues in the link between docosahexaenoic acid and Alzheimer's disease. | 2007 Nov-Dec | Prostaglandins Leukot. Essent. Fatty Acids | pmid:18036804 |
| Erdogan H et al. | Effect of fish oil supplementation on plasma oxidant/antioxidant status in rats. | 2004 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:15253883 |
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| Krabbendam L et al. | Relationship between DHA status at birth and child problem behaviour at 7 years of age. | 2007 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:17074476 |
| Qin X et al. | Brown but not white adipose cells synthesize omega-3 docosahexaenoic acid in culture. | 2016 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:26802938 |
| Hall JA et al. | Maternal dietary n-3 fatty acids alter immune cell fatty acid composition and leukotriene production in growing chicks. | 2007 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:17081738 |
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| Brenner RR | Hormonal modulation of delta6 and delta5 desaturases: case of diabetes. | 2003 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:12538079 |
| Nyuar KB et al. | Regular consumption of Nile river fish could ameliorate the low milk DHA of Southern Sudanese women living in Khartoum City area. | 2013 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:23706881 |
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| Sarri KO et al. | Adipose DHA inversely associated with depression as measured by the Beck Depression Inventory. | 2008 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:18258421 |
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| Block RC et al. | The effects of EPA, DHA, and aspirin ingestion on plasma lysophospholipids and autotaxin. | 2010 Feb-Mar | Prostaglandins Leukot. Essent. Fatty Acids | pmid:20106646 |
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| Van Biervliet S et al. | Oral DHA supplementation in DeltaF508 homozygous cystic fibrosis patients. | 2008 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:18276127 |
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| Yusof HM et al. | Influence of very long-chain n-3 fatty acids on plasma markers of inflammation in middle-aged men. | 2008 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:18403189 |
| Brouwer IA | Omega-3 PUFA: good or bad for prostate cancer? | 2008 Sep-Nov | Prostaglandins Leukot. Essent. Fatty Acids | pmid:18951003 |
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