DHA

Dha is a lipid of Fatty Acyls (FA) class. Dha is associated with abnormalities such as Atherosclerosis, Consumption-archaic term for TB, Chronic disease, Cardiovascular Diseases and Diabetes Mellitus, Non-Insulin-Dependent. The involved functions are known as Inflammation, Oxidation, fatty acid oxidation, Fatty Acid Metabolism and Lipid Metabolism. Dha often locates in Hepatic, Protoplasm, Mucous Membrane, Epithelium and outer membrane. The associated genes with DHA are IMPACT gene, FATE1 gene, GAPDH gene, THOC4 gene and SLC33A1 gene. The related lipids are stearidonic acid, Fatty Acids, Total cholesterol, Lipopolysaccharides and Dietary Fatty Acid. The related experimental models are Mouse Model, Transgenic Model, Animal Disease Models and Arthritis, Experimental.

Cross Reference

Introduction

To understand associated biological information of DHA, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with DHA?

DHA is suspected in Cardiovascular Diseases, Obesity, Ischemia, Hypertensive disease, Coronary Arteriosclerosis, Cerebrovascular accident and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with DHA

MeSH term MeSH ID Detail
Malnutrition D044342 6 associated lipids
Insulin Resistance D007333 99 associated lipids
Diabetes Complications D048909 4 associated lipids
Sleep Apnea, Obstructive D020181 9 associated lipids
Peripheral Arterial Disease D058729 7 associated lipids
Intracranial Arteriosclerosis D002537 4 associated lipids
Macular Degeneration D008268 5 associated lipids
Dyslipidemias D050171 7 associated lipids
Asthma, Exercise-Induced D001250 10 associated lipids
Deficiency Diseases D003677 12 associated lipids
Per page 10 20 50 100 | Total 240

PubChem Associated disorders and diseases

What pathways are associated with DHA

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with DHA?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with DHA?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with DHA?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with DHA?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with DHA?

Mouse Model

Mouse Model are used in the study 'Homeostatic regulation of photoreceptor cell integrity: significance of the potent mediator neuroprotectin D1 biosynthesized from docosahexaenoic acid: the Proctor Lecture.' (Bazan NG, 2007), Mouse Model are used in the study 'Omega-3 fatty acids EPA and DHA: health benefits throughout life.' (Swanson D et al., 2012), Mouse Model are used in the study 'Docosahexaenoic acid attenuates hepatic inflammation, oxidative stress, and fibrosis without decreasing hepatosteatosis in a Ldlr(-/-) mouse model of western diet-induced nonalcoholic steatohepatitis.' (Depner CM et al., 2013) and Mouse Model are used in the study 'Wax esters from the marine copepod Calanus finmarchicus reduce diet-induced obesity and obesity-related metabolic disorders in mice.' (Höper AC et al., 2014).

Transgenic Model

Transgenic Model are used in the study 'Loss of MAP function leads to hippocampal synapse loss and deficits in the Morris Water Maze with aging.' (Ma QL et al., 2014).

Animal Disease Models

Animal Disease Models are used in the study 'Fish oil increases muscle protein mass and modulates Akt/FOXO, TLR4, and NOD signaling in weanling piglets after lipopolysaccharide challenge.' (Liu Y et al., 2013).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with DHA

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Per page 10 20 50 100 | Total 7336
Authors Title Published Journal PubMed Link
Agren JJ et al. Hemostatic factors and platelet aggregation after a fish-enriched diet or fish oil or docosahexaenoic acid supplementation. 1997 Prostaglandins Leukot. Essent. Fatty Acids pmid:9430389
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Martin RE et al. Docosahexaenoic, arachidonic, palmitic, and oleic acids are differentially esterified into phospholipids of frog retina. 2002 Aug-Sep Prostaglandins Leukot. Essent. Fatty Acids pmid:12324228
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Huang LL et al. Suppression of acute ethanol-induced hepatic steatosis by docosahexaenoic acid is associated with downregulation of stearoyl-CoA desaturase 1 and inflammatory cytokines. 2013 Prostaglandins Leukot. Essent. Fatty Acids pmid:23474173
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He J and Bazan HE Omega-3 fatty acids in dry eye and corneal nerve regeneration after refractive surgery. 2010 Apr-Jun Prostaglandins Leukot. Essent. Fatty Acids pmid:20202804
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Brenner RR Hormonal modulation of delta6 and delta5 desaturases: case of diabetes. 2003 Prostaglandins Leukot. Essent. Fatty Acids pmid:12538079
Nyuar KB et al. Regular consumption of Nile river fish could ameliorate the low milk DHA of Southern Sudanese women living in Khartoum City area. 2013 Prostaglandins Leukot. Essent. Fatty Acids pmid:23706881
Qiu X Biosynthesis of docosahexaenoic acid (DHA, 22:6-4, 7,10,13,16,19): two distinct pathways. 2003 Prostaglandins Leukot. Essent. Fatty Acids pmid:12538082
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Meldrum SJ et al. Determinants of DHA levels in early infancy: differential effects of breast milk and direct fish oil supplementation. 2012 Prostaglandins Leukot. Essent. Fatty Acids pmid:22572105
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Delplanque B et al. A dairy fat matrix providing alpha-linolenic acid (ALA) is better than a vegetable fat mixture to increase brain DHA accretion in young rats. 2013 Prostaglandins Leukot. Essent. Fatty Acids pmid:22884780
Kuipers RS et al. Gestational age dependent content, composition and intrauterine accretion rates of fatty acids in fetal white adipose tissue. 2012 Jan-Feb Prostaglandins Leukot. Essent. Fatty Acids pmid:22093549
Attar-Bashi NM et al. Failure of conjugated linoleic acid supplementation to enhance biosynthesis of docosahexaenoic acid from alpha-linolenic acid in healthy human volunteers. 2007 Prostaglandins Leukot. Essent. Fatty Acids pmid:17275274
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